Lymph nodes draining

Thymus, spleen, draining lymph node and at least one additional lymph node, bone marrow,2 Peyer s patc,h3 BALT,4 NALT4... 

Manetz, T.C., Pettit, D.A. and Meade, B.J., The determination of draining lymph node cell cytokine mRNA levels in BALB/c mice following dermal sodium lauryl sulfate, di-nitrofluorobenzene, and toluene diisocyanate exposure. Toxicol. Appl. Pharm., 171, 174, 2001. 

McLachlan JB, Hart JP, Pizzo SV, et al Mast cell-derived tumor necrosis factor induces hypertrophy of draining lymph nodes during infection. Nat Immunol 2003 4 1199-1205. 

Doganci A , Karwot R , Maxeiner JH 24 ( contributed equally), et al 1L-2R beta Chain Signaling Controls Immunosuppressive CD4 T Cells in the Draining Lymph Nodes and Lung during Allergic Airway Inflammation 25... 

Dulforce PA, Garman KL, Seitz GW, Fleischmann RI, Crespo SM, Planck SR, Parker DC, Rosenbaum JT APCs in the anterior uveal tract do not migrate to draining lymph nodes. J Immunol 2004 172 6701-6708. 

Recent guidelines entitled Non-clinical Local Tolerance Testing of Medicinal Product from the CPMP refer to the murine local l)unph node assay as a method for the assessment of the induction phase of skin sensitisation. This method measures the ability of compoimds to induce proliferative responses in skin-draining lymph nodes. This method uses fewer animals than alternative in vivo methods and reduces the trauma to which animals are potentially subjected. ... 

Chemicals and pharmaceuticals may be tested for their capacity to induce skin sensitization [49]. The potency of a xenobiotic or pharmaceutical compound to induce delayed type hypersensitivity (DTH) or contact dermatitis (CD) may be tested in the so called local lymph node assay (LENA) in which the induction of an immune response in lymph nodes is determined after local (skin) exposure [49-51]. The induction of cellular proliferation in draining lymph nodes is measured by determining the... 

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