Cefazolin sodium

Aminocephalosporanic acid Cefazolin sodium Ceftizoxime Cephacetriie sodium Cephalogiycin Cephaloridine Cephalothin sodium Cephapirin sodium 2-Amino-5-chlorobenzonitrile Ciorazepate dipotassium 2-Amino-5-chlorobenzophenone Chlordiazepoxide HCi Pinazepam Prazepam... 

Feximac cream - Bufexamac F.H. -Tegafur Fiblaferon - Interferon Fibocil - Aprindine HCI Fiboran - Aprindine HCI Fibutox -Oxyphenbutazone Ficoid - Fluocortolone Fidesbiotic -Ampicillln Fidesporin - Cefazolin sodium Fidocin Demedocydine HCI Filacul - Tegafur Filair -Terbutaline... 

A medication order calls for 400 mg of Kefzol (cefazolin sodium) to be administered IM to a patient every 12 hours. Vials containing 250 mg, 500 mg, and 1 g of cefazolin sodium are available. According to the manufacturer s directions, dilutions may be made as follows ... 

Explain how the prescribed amount of cefazolin sodium could be obtained. From 250 mg vial ... 

A vial contains 1 g of Ancef (cefazolin sodium). Express the concentrations of cefazolin sodium, in milligrams per milliliter, following reconstitution with sterile water for injection to the following volumes ... 

A pharmacist reported that 1- and 10-g vials of Marsam cefazolin sodimn appear to be identical in shape and have the same color flip-top closures. The pharmacy ordered the 1-g product from the wholesaler. However, the wholesaler sent 10-g bulk vials of cefazolin sodium along with stickers for the 1-g vial. The pharmacy, which does not normally stock the 10-g vials, interspersed the 10-g vials with the 1-g vials in their stock. Several vials were reconstituted in error. Fortunately no patient received the wrong dose. 

In another reported incident, a pharmacist ordered the 10-g vials of cefazolin sodium but received the 1-g vials in error. Intending to reconstitute and divide the 10-g vials into 1-g doses, a technician inadvertently reconstituted the 1-g vials and proceeded to divide the total solution of each vial into ten 100-mg doses. Some of the prepared 100-mg doses of cefazolin sodium were administered to patients instead of their scheduled 1-g doses, but no adverse effects were reported. The pharmacist thought that the error occurred partly because the vials are identical in size and have similar labels. 

CEFAZOLiN SODiUM Total daily dosages are the same for IM and IV administration. 

Incompatibilities Do not mix IV minocycline before or during administration with any solutions containing the following Adrenocorticotropic hormone (ACTH), aminophylline, amobarbital sodium, amphotericin B, bicarbonate infusion mixtures, calcium gluconate or chloride, carbenicillin, cephalothin sodium, cefazolin sodium, chloramphenicol succinate, colistin sulfate, heparin sodium, hydrocortisone sodium succinate, iodine sodium, methicillin sodium, novobiocin, penicillin, pentobarbital, phenytoin sodium, polymyxin, prochlorperazine, sodium ascorbate, sulfadiazine, sulfisoxazole, thiopental sodium, vitamin K (sodium bisulfate or sodium salt), whole blood. 

Cephalosporins, 1st generation cefadroxil cefazolin sodium cephalexin... 

Furlanetto et al. (26) attempted to predict and compare the solid-state stability of cefazolin sodium and cephaloridine sterile powders using data obtained at 37°C, 45°C, and 60°C. They analyzed samples for up to 6 months and found cephaloridine to be more stable than cefazolin sodium, in contrast to the relative stability of the compounds as indicated by their respective compendial storage instructions. They attributed greater stability of the cephaloridine samples to greater crystallinity compared to the cefazolin sodium samples which appeared to be mostly amorphous. Rather than comparing different samples of the same drug, this study determined the relative stability of two different drugs and compared the results to expectations based on previous information. 

Furlanetto S, Mura P, Gratteri P, Pinzauti S. Stability prediction of cefazolin sodium and cephaloridine in solid state. Drug Dev Ind Pharm 1994 20 2299-2313. 

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