Analytical profiles

T. Cairns and J. Sherma, eds.. Comprehensive Analytical Profiles of Important Pesticides, CRC Press, Boca Raton, Fla., 1992, 304 pp. From the series ModemMethods for Pesticide Analysis, provides detailed information on properties and analytical methodology for nine prominent pesticides, pyrethroids, and fumigants in food. Includes formulations and uses, chemical and physical properties, toxicity data, and tolerances on various foods and feeds. Analytical information may be given in enough detail for methods to be carried out without having to consult additional Hterature sources. 

G. A. Biewei, in K. Floiey, eA, Analytical Profiles of Drug Substances, Vol. 8, Academic Press, New York, p. 179. 

Fig. 9. Comparison of the analytical SCF model [56] with the full numerical SCF calculation [53] for the segment density profile in flat, grafted layers at various surface densities (o is the fraction of the maximum possible surface coverage of grafted ends). The analytical profile is parabolic to its tip, while the numerical calculation shows that the density at the periphery of the layer drops off exponentially...

H. G. Brittain, Ed., Analytical Profiles of Drug Substances and Excipients, Vol. 27, Academic Press, Inc., San Diego, 2000. 

Two sensibly priced commercial databases for solubility exist [366,507], An article in the journal Analytical Profiles of Drug Substances carries solubility data [496]. Abraham and Le [508] published a list of intrinsic aqueous solubilities of 665 compounds, with many ionizable molecules. It is difficult to tell from published lists what the quality of the data for ionizable molecules is. Sometimes, it is not clear what the listed number stands for. For example, Sw, water solubility, can mean several different things either intrinsic value, or value determined at a particular pH (using buffers), or value measured by saturating distilled water with excess compound. In the most critical applications using ionizable molecules, it may be necessary to scour the original publications in order to be confident of the quality of reported values. 

A 2D liquid mass mapping method has been developed in our laboratory for the analytical profiling of proteins in complex biological material. In the present study, we demonstrate the capability of this method for comparative protein mapping of isogenic... 

The elements to be controlled (elements, analytical profiles, protection... 

The writing of an analytical profile of aspirin, this drug of drugs, poses two major dilemmas. The first is in the name itself. There are many countries where Aspirin is still a trade-name of the German firm Bayer AG, and Acetylsali-cylic Acid is used as the generic. Yet, I decided to use the former because it is the U.S.P. and B.P., the better known worldwide and the more elegant name. 

Aspirin has now been available for close to 80 years, and its usefulness and popularity are undiminished. Consequently, the literature is voluminous and also undiminished. A complete coverage would be beyond the scope of an analytical profile. I have endeavored to cover the newer literature as comprehensibly as possible and have included only those older references which I found of historical interest. To all those who have labored in the vineyard of aspirin and who go unreferenced in this profile, I tender my sincere apologies. 

W.D.Schonleber, A.L.Jacobs, and G.A.Brewer,jr. "Dihydro-ergotoxine mesilate" in Analytical Profiles of Drug Substances 1, 81... 

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