Carcinogenesis induced

TATSUTA M, iisHi H, BABA M, YANO H, UEHARA H, NAKAizuMi A (1999) Attenuation by genistein of sodiirm-chloride enhanced gastric carcinogenesis induced by N-methyl-N -nitro-N-nitrosoguanidine. Int J Cancer. 80 396-9. 

In mice, also, deacetylation is involved in the hepato-carcinogenesis induced by 2-(acetylamino)fluorene. Indeed, BNPP-inhibited DNA-adduct formation in murine liver microsomes as well as tumor initiation by A-hydroxy-2-(acetylamino)fluorene in infant male B6C3Fj mice [100],... 

Kraybill HF. 1978. Carcinogenesis induced by trace contaminants in potable water. Bull NY Acad Med 54 413-427. 

H. Narahara, M. Tatsuta, H. lishi, M. Baba, N. Uedo, N. Sakai, H. Yano and S. Ishiguro, K-ras point mutation is associated with enhancement by deoxycholic acid of colon carcinogenesis induced by azoxymethane, but not with its attenuation by all-trans-retinoic acid, Int. J. Cancer, 2000, 88(2), 157. 

In contrast to the effects of secondary bile acids like DCA, UDCA, which is found at a high concentration in bear bile but only in trace amounts in humans, has anti-neoplastic activity in vitro and in vivo. UDCA has significant chemopreventative activity in rodent models of sporadic and colitis-colorectal carcinogenesis induced by chemical carcinogens. 

Relationship between amount and type of dietary fat in promotion of mammary carcinogenesis induced by 7,12-dimethylbenz[a] anthracene. J Natl Cancer Inst 1979 62(4) 1009-1012. 

Caderni, G., Filippo, C.d., Luceri, C., Salvadori, M., Giannini, A., Biggeri, A., Remy, S., Cheynier, V., and Dolara, P., Effects of black tea, green tea and wine extracts on intestinal carcinogenesis induced by azoxymethane in F344 rats. Carcinogenesis, 21, 1965, 2000. 

Barbin, A., Role of etheno DNA adducts in carcinogenesis induced by vinyl chloride in rats, IARC Sci. Publ., 150, 303-313, 1999. 

TP Brent St. Jude Children s Research Hospital Develop histochemical assays for MGMT (06-alkylguanine-DNA alkylt-ransferase, previously called GATase) expression in human tumor and tissue preparations Detailed analysis of the structure, function, and regulation of MGMT activity will ultimately enable the to prediction of tumor resistance, as well as an individual s susceptibility to carcinogenesis induced by chemicals such as 2,3,7,8-TCDD ... 

Similarly, it has been demonstrated that various antioxidants inhibit carcinogenesis induced by a wide variety of compounds and in several organ sites (19, review). The antagonism between dietary fats and antioxidants on carcinogenesis suggests that a common factor... 

Anderson SP, Cattley RC, Corton JC. 1999. Hepatic expression of acute-phase protein genes during carcinogenesis induced by peroxisome proliferators. Mol Carcinog 26 226-238. 

R. Saffhill et al., Mechanisms of carcinogenesis induced by alkylating agents. Biochim. Biophys. Acta 823, 111-145 (1985)... 

Grubbs CJ, Moon RC, Squire RA, Farrow GM, Stinson SF, Goodman DG, Brown CC, Sporn MB. 13-cis-retinoic acid inhibition of bladder carcinogenesis induced in rats by A-butyl-A-(4-hydroxybutyl)nitrosamine. Science 1977 198 743-4. 

In summary, substantial progress has been made over the past few years in understanding the cytoplasmic organelle peroxisome and factors that alter its normal functions. Peroxisome proliferator-in-duced increase in the liver peroxisomes is associated with an approximately two-fold increase in catalase activity and several-fold increases in the activity of the peroxisomal fatty acid jS-oxidation system. It is also evident from the available literature that hepatic peroxisomal proliferation appears to be a carcinogenic event in rodents, and this may depend on the potency of the inducer. However, there is no single mechanism that is attributed to the peroxisome proliferation or carcinogenesis induced by... 

Dll. Di Paolo, J. A., Effects of oxygen concentration on carcinogenesis induced by transplacental exposure to urethan. Cancer Res. 22, 299-304 (1962). 

Karkare MR, Clark TD, Glauert HP. 1991. Effect of dietary calcium on colon carcinogenesis induced by a single injection of 1,2-dimethylhydrazine in rats. Am Instit Nutr 568-577. 

Saffiotti U, Montesane R, Sellakumar AR, et al. 1972. Respiratory tract carcinogenesis induced in hamsters by different dose levels of benzo[a]pyrene and ferric oxide. J Natl Cancer Inst 49 1199-1204. 

Wattenberg LW, Bueding E. 1986. Inhibitory effects of 5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione (Oltipraz) on carcinogenesis induced by benzo[a]pyrene, diethyinitrosammie and uracil mustard. Carcinogenesis 7 1379-1381. 

Lapathoside A Anti-tumor-promoting effects on mouse two-stage skin carcinogenesis induced by DMBA and TPA Active [64]... 

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