Skin, ultraviolet-induced carcinogenesis

Burns, F.J., Uddin, A.N., Wu, F. et al. (2004) Arsenic-induced enhancement of ultraviolet radiation carcinogenesis in mouse skin a dose-response study. Environmental Health Perspectives, 112(5), 599-603. 

Kimura Y, Sumiyoshi M (2009) Olive leaf extract and its main component oleuropein prevent chronic ultraviolet B radiation-induced skin damage and carcinogenesis in hairless mice. J Nutr 139 2079-2086... 

Wang ZY, Huang M, Lou Y, Xie J, Reuhl K, Newmark H, Ho C, Yang C and Conney A. 1994. Inhibitory effects of black tea, green tea, decaffeinated black tea, and decaffeinated green tea on ultraviolet B light-induced skin carcinogenesis in 7,12-dimethylbenz[<3]anthracene-initiated SKH-1 mice. Cancer Res 54(13) 3428-3435. 

S. M. Fischer, H.-H. Lo, G.B. Gordon, K. Seibert, G. Kelloff, R.A. Lubet, C.J. Conti, Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, and indomethacin against ultraviolet light-induced skin carcinogenesis. Mol. Carcinog. 25 (1999) 231. 

CN210 Berton, T. R., S. M. Fischer, C. J. Conti, and M. F. Locniskar. Comparison of ultraviolet light-induced skin carcinogenesis and ornithine decarboxylase activity in sencar and hairless SKH-1 mice fed a constant level of dietary lipid varying in com and coco-... 

The last experiment was repeated in part using hr/hr Oslo strain mice and extended by the use of SEN mice. The data were mainly presented as summary statistics. In contrast to the earlier results, the gel without benzoyl peroxide did not enhance DMBA carcinogenesis in hr/hr mice and Panoxyl did not enhance DMBA carcinogenesis in SEN mice. Groups of 32 hr/hr mice were also treated with ultraviolet radiation (UV) from new Phillips HP 3114 sunlamps, either alone twice a week or 5-30 min before treatment with Panoxyl or the gel without benzoyl peroxide. The numbers of mice with skin carcinomas (and the total numbers of skin tumours in each group of mice) were UV alone, 26/32 (103 papillomas, 45 carcinomas) UV + Panoxyl, 22/32 (94 papillomas, 30 carcinomas) UV + gel, 23/32 (126 papillomas, 29 carcinomas). Thus, neither Panoxyl nor the gel without benzoyl peroxide had any significant effect upon the multiplicity of UV-induced skin tumours (Iversen, 1988). 

Birt, D.R, Mitchell, D., Pour, P, and Pinch, H., Inhibition of ultraviolet light induced skin carcinogenesis in SKH-1 mice by apig nin, Anticancer Res., 17, 85-92, 1996. Fremont, L., Biological effects of resveratrol. Life ScL, 66, 663-673, 2000. 

Athar, M., Agarwal, R., Wang, Z.Y., Lloyd, J.R., Bickers, D.R., and Mukhtar, H., All trans retinoic acid protects against free radical generating compounds-mediated conversion of chemically and ultraviolet B radiation-induced skin papillomas to carcinomas. Carcinogenesis, 12, 2325-2329, 1991. 

Fischer, S.M., Lo, H.-H., Gordon, G.B., Seibert, K., Kelloff, G., Lubet, R. A., and Conti, C.J. (1999) Chemopreventive Activity of Celecoxib, a Specific Cyclooxygenase-2 Inhibitor, and Indomethacin Against Ultraviolet Light-Induced Skin Carcinogenesis, Mol. Carcinog. 25, 231-240. 

Gu M, Dhanalakshmi S, Mohan S, Singh RP, Agarwal R (2005) Silibinin inhibits ultraviolet B radiation-induced mitogenic and survival signaling, and associated biological responses in SKH-1 mouse skin. Carcinogenesis 26 1404—1413... 

Katiyar SK, Afaq F, Perez A, Mukhtar H. Green tea polyphenol (-)-epigaUocatechin-3-gallate treatment of human skin inhibits ultraviolet radiation-induced oxidative stress. Carcinogenesis 2001 22 287-294. 

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