Carbon catabolite repression

PG production was constitutive and not subject to carbon catabolite repression. Highest yields were on glucose and fructose (upto 10% w/v) (Table 1). Inclusion of pectic compounds had no effect on growth or PG production (data not shown). 

Duetz WA, S Marques, C de Jong, JL Ramos, J G van Andel (1994) Inducibility of the TOL catabolic pathway in Pseudomonas putida (pWWO) growing on succinate in continuous culture evidence of carbon catabolite repression control. J Bacteriol 176 2354-2361. 

MLS1 Malate synthase, enzyme of the glyoxylate cycle, involved in utilization of non-fermentable carbon sources expression is subject to carbon catabolite repression localizes in peroxisomes during growth in oleic acid medium... 

As in the commercial PN strains, glucose and sucrose were found to repress PN production in A. nidulans. Compared to lactose-grown cultures, ipnA lacZ expression was reduced with these two carbon sources. " The glucose-dependent repression of many genes in primary metabolism is mediated by the well-characterized carbon catabolite repression (ere) system. While CreA mediates... 

ESPESO, E.A., PENALVA, M.A., Carbon catabolite repression can account for the temporal pattern of expression of a penicillin biosynthetic gene in Aspergillus nidulans. Mol. MicriobioL, 1992, 6,1457-1465. 

Stulke, J. and Hillen, W. (1999) Carbon catabolite repression in bacteria. Curr. Opin. Microbiol, 2, 195-201. 

Arndt, A. and Eikmanns, B.J. (2007) The alcohol dehydrogenase gene adhA in Corynebacterium glutamicum is subject to carbon catabolite repression. /. Bacteriol, 189 (20), 7408-7416. 

Rojo, F. (2010) Carbon catabolite repression in Pseudomonas optimizing metabolic versatility and interactions with the environment. FEMS Microbiol. Rev., 34 (5), 658 -684. 

H., Burchhardt, G., and Herrmann, H. (1996) Carbon catabolite repression of phenol degradation in Pseudomonas putida is mediated by the inhibition of the activator protein PhlR. /. Bacteriol, 178 (7), 2030-2036. 

Gorke, B. and Stulke, J. (2008) Carbon catabolite repression in bacteria many ways to make the most out... 

Rafudeen, M.S. (2002) Investigation of carbon catabolite repression in Clostridium beijerinckii NCIMB 8052. PhD thesis. University of Cape Town. 

Gancedo, J. M. (1998). Yeast carbon catabolite repression. Microbiology and Molecular Biology Reviews, 62, 334—361. 

Glucose effect, carbon catabolite repression (BF positive)... 

Ji XJ, Nie ZK, Huang H, Ren LJ, Peng C, Ouyang PK. (2011b). Elimination of carbon catabolite repression in Klebsiella oxytoca for efficient 2,3-butanediol production from glucose-xylose mixtures. Appl Microbiol Biotechnol, 89, 1119-1125. 

Kwakman M, Posema W Glucose kinase has a regulatory role in carbon catabolite repression in Streptomyces coeiicolor. J Bactetiol 1994 176 2694-2698. 

Microbes can normally utilize a variety of substrates for their growth and metabolism. Glucose is one of the carbon sources that can be firstly and rapidly assimilated and utilized by many microbes via the systems such as phosphotransferase system (PTS). When glucose exists as a substrate in a mixture with other carbons, it could inhibit the utilization of other carbon sources due to the presence of carbon catabolite repression (CCR) that is induced by the PTS global signal regulation. ... 

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