Cancer inflammation

Benign prostate hyperplasia, male pattern baldness Cancer Inflammation... 

This review reports the more recent evidence for the ability of P-carotene and other carotenoids to modulate cell signaling related to cell growth and implicated in a lot of pathological events, including cancer, inflammation, and atherosclerosis by both redox and non-redox mechanisms. 

Nonpeptide receptors Adenosine Aj Human cDNA Cardiac arrhythmia, asthma, myocardial ischemia, obesity, pain, renal disease, sleep apnea, stroke, cancer, inflammation, glaucoma, cystic fibrosis, Alzheimer s disease, Parkinson s disease Bradycardia, lipolysis inhibition, reduction of glomerular filtration and natriuresis, tubero-glomerular feedback, antinociception, renal vasodilatation-constriction, reduction of central cholinergic and noradrenergic nerve activity, presynaptic inhibition of excitatory neuro transmission... 

In addition, the SI 00-RAGE interaction and the activation of various cellular pathways will be discussed. Finally, the close association of S100 proteins with cardiomyopathy, cancer, inflammation and brain diseases is summarized as well as their use in diagnosis and their potential as drug targets to improve therapies in the future... 

Nucleosides are metabolites of ribonucleic acid (RNA). As a result of excessive turnover of RNA, which occurs in such pathological conditions as cancer, inflammation, and AIDS, nucleosides are excreted into urine in increased amounts. Normal nucleosides (adenosine, guanosine, cytidine, uridine) either undergo further degradation into uric acid, p-alanine, or p-aminoisobutyrate or are reutilized. On the other hand, modified nucleosides, especially methylated nucleosides, are excreted unchanged in urine. Therefore, it seems that elevated levels of modified nucleosides could be an indicator of the presence of cancer and used as a diagnostic tool in cancer prognosis [23]. 

Gallium is a metallic element (symbol Ga atomic no. 31) that has been used in the form of a radiopharmacentical ( Ga as the citrate) in diagnostic imaging of cancers, inflammation, and infection (1-3). The mechanisms of the therapeutic activity of galhum have been reviewed (4). 

The phytochemical complexity of kiwis has attracted scientific interest for the potential health effects involved, including laboratory studies to probe for activity against cancer, inflammation, diabetes, metabolic syndrome, microbial infections, and immune disorders. 

In both sexes, digital rectal examination provides an opportunity to check ambient rectal tone, the integrity of the sacral reflex arc (e.g., anal wink), as well as assess the patient s ability to perform a voluntary pelvic floor muscle contraction (i.e., Kegel exercise), which may be an important factor in deciding on appropriate therapy. In men, a digital examination of the prostate assesses for the presence of prostate cancer, inflammation, and BPH. 

Protein acetylation HDAC family Cancer, Inflammation, N eurodegenerative diseases... 

The significant achievements of the last ten years are that the saponins display interesting effects in a great diversity of new biological systems using enzymes or defined cell systems for example in the field of cancer, inflammation, and liver diseases. But the molecular biological data, have to be further investigated in order to explain mechanisms of action which remain still in dark and to confirm and reproduce the observed effects. 

Wong, G.H.W., Neta, R. and Goeddel, D.V. (1992) Protective roles of MnSOD, TNF-ct, TNF-/5 and D-faetor (LIF) in radiation injury. In K. Steglitz (Ed.), Eicosanoids and Other Bloactive Lipids in Cancer, Inflammation and Radiation Injury, 2nd International Conference, Berlin, pp. 353-358. 

Oxidative cellular damage by reactive oxygen species such as superoxide anion, hydroperoxy and hyassociated with various human chronic diseases, e.g. cancers, inflammation, arthritis, atherosclerosis and also with the process of ageing. Claims that diet and increased intake of nutrients exhibiting antioxidative activity have a preventative effect on chronic diseases have increased in recent years. In this context, polyphenolic compounds such as tannins, flavonoids, coumarins, lignans and caffeic acid derivatives, which are abundantly contained in a large number of medicinal plants, foods and beverages, are of particular interest for human health care because of the antioxidative properties widely found in plant phenolics. The antioxidative activity of tannins has been extensively studied in various in vitro and in vivo experimental systems and summarized in reviews [96, 97]. Such activity includes the inhibition of lipid peroxidation induced by NADPH-ADP and ascorbic acid-ADP in rat liver microsomes and mitochondria, respectively... 

De Petrocellis, L, Melck, D., Bisogno, T., and Di Marzo, V. (2000) Endocannabinoids and fatty acid amides in cancer, inflammation and related disorders. Chemistry and Physics of Lipids 108 191-209. 

Skin Diseases. Arsenic was used externally and internally to improve the nutrition of the skin and hair. A popular belief was that arsenic is not only useful but essential and almost unexceptionally successful when properly administered in all cases of chronic idiopathic affections of the skin provided always and in all cases, that it be administered discretely, perseveringly and with such adjuncts as the case may require (45, p 834). Skin diseases treated with arsenotherapy included psoriasis, chronic eczema, warts, lupus, epithelioma, recurrent herpes, vesicular or bullous eruptions of children, ulcers, gangrene of the penis, external cancers, inflammation of the skin, pustular and popular forms of acne, leprosy, impetigo, etc. 

Khalfoun, B., et al., Docosahexaenoic and eisosapentaenoic acids inhibit in vitro human endothelial cell production of interleukin-6, in Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 2, Honn, K.V., et al., lids. Plenum Press, New York, 1997. 

EICOSANOIDS AND OTHER BIOACTIVE LIPIDS IN CANCER, INFLAMMATION, AND RADLVTION INJURY, 4... 

First, in India, the Iris juice from fresh erushed roots of Iris species with wine has bee used traditionally for the treatment of dropsy as an oral medicine from since long ago. The Iris juice has been also used in a cosmetic for the removal of skin freckles. Moreover, the Iris plant has been used in the treatments such as cancer, inflammation, bacterial and viral infections [41]. 

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