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Cancer glycopeptides

P. Niederhafner, M. Reims, J. Sebestik, and J. Jezek, Glycopeptide dendrimers, Part III—A review Use of glycopeptide dendrimers in immunotherapy and diagnosis of cancer and viral diseases, J. Pept. Sci., 14 (2008) 556-587. [Pg.385]

Koganty, R.R., Reddish, M.A., and Fongenecker, B.M. (1996) Glycopeptide- and carbohydrate-based synthetic vaccines for the immunotherapy of cancer. Drug Disco. Today, 1, 190-198. [Pg.1084]

Several antibiotics used in the treatment of cancer belong to a group of glycopeptides... [Pg.159]

L. A. Marcaurelle, M. R. Pratt, and C. R. Bertozzi, Synthesis of thioether-linked analogues of the 2,3-sialyl-TF and MECA-79 antigens Mucin-type glycopeptides associated with cancer and inflammation, ChemBioChem, 2-3 (2003) 224-228. [Pg.390]

Kuduk, S., Schwarz, J., Chen, X.-T., et al. (1998) Synthetic and immunological studies on clustered modes of mucin-related Tn and TF G-linked antigens The preparation of a glycopeptide-based vaccine for clinical trials against prostate cancer. /. Am. Chem. Soc. 120,12474-12485. [Pg.206]

Kim and coworkers examined glycopeptides from normal, and cancerous, colonic mucosa.869 Pronase digestion of disrupted cell-membranes gave a soluble glycopeptide fraction. The fractions obtained from normal tissues inhibited Dolichos biflorus, but not Ricinus communis, hemagglutination, whereas the reverse was true of fractions obtained from malignant, colonic mucosa. No further analysis was carried out.869... [Pg.330]

Microbial sources have been a very rich source for cancer chemotherapeutic agents. Of particular note is the Strep-tomyces spp., which has been responsible for the production of many approved anticancer agents that are in clinical practice. These agents are represented by highly diverse structural classes exemplified by the anthracycline family (e.g., doxom-bicin, 73) (72-74), actinomycin family (e.g., dactinomycin, 74), glycopeptides family (e.g., bleomycins A2 and B2, 75 and 76) (75), and mitomycin family (e.g., mitomycin C, 77) (72, 76). All these compounds specifically interact with DNA for then-mode of action. [Pg.1469]

TF O-linked antigens the preparation of a glycopeptide-based vaccine for clinical trials against prostate cancer, J. Am. Chem. Soc., 120, 12474-12485, 1998. [Pg.808]

To date, the Tn antigen has been studied to a greater level as a vaccine than the other antigenic glycopeptide cancer epitopes. The reason for this can be attributed to its simplicity and ease of synthesis. Recently, more complex antigens have been synthesized, using the approaches established on the Tn core structure as a foundation for which to build upon. [Pg.1816]

Clustered glycopeptide antigens as cancer vaccine candidates. [Pg.1822]

Mucins Vaccines Cancer Carbohydrates Antigens Glycosylation Glycopeptides... [Pg.2646]


See other pages where Cancer glycopeptides is mentioned: [Pg.217]    [Pg.435]    [Pg.6]    [Pg.319]    [Pg.323]    [Pg.257]    [Pg.261]    [Pg.222]    [Pg.50]    [Pg.96]    [Pg.96]    [Pg.263]    [Pg.344]    [Pg.968]    [Pg.361]    [Pg.24]    [Pg.700]    [Pg.415]    [Pg.35]    [Pg.54]    [Pg.231]    [Pg.472]    [Pg.159]    [Pg.332]    [Pg.783]    [Pg.854]    [Pg.1219]    [Pg.1221]    [Pg.1795]    [Pg.1795]    [Pg.1796]    [Pg.1798]    [Pg.1810]    [Pg.1810]    [Pg.1815]    [Pg.1821]    [Pg.1822]    [Pg.2645]    [Pg.2656]   
See also in sourсe #XX -- [ Pg.96 , Pg.97 ]




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