Glycopeptide dendrimer

P. Niederhafner, J. Sebestik, and J. Jezek, Glycopeptide dendrimers. Part I,... 

P. Niederhafner, M. Reims, J. Sebestik, and J. Jezek, Glycopeptide dendrimers, Part III—A review Use of glycopeptide dendrimers in immunotherapy and diagnosis of cancer and viral diseases, J. Pept. Sci., 14 (2008) 556-587. 

J. Vondrasek, and M. Pisacka, Solid phase synthesis of glycopeptide dendrimers with Tn antigenic structure and their biological activities. Part I, J. Pept. Sci., 5 (1999) 46-55. 

E. M. V. Johansson, E. Kolomiets, F. Rosenau, K.-E. Jaeger, T. Darbre, and J.-L. Reymond, Combinatorial variation of branching length and multivalency in a large (390, 625 member) glycopeptide dendrimer library Ligands for Fucose-specific lectins, New J. Chem., 31 (2007) 1291-1299. 

C. Ozawa, H. Hojo, Y. Nakahara, H. Katayama, K. Nabeshima, T. Akahane, and Y. Nakahara, Synthesis of glycopeptide dendrimer by a convergent method, Tetrahedron, 63 (2007) 9685-9690. 

Scheme 66 Two Types of Thiosialo Glycopeptide Dendrimers (A) Multidirectional and (B) Divergent 502,5031...

Veprek P, Jezek J (1999) Peptide and glycopeptide dendrimers. Part I. J Pept Sci 5 5-23... 

In the present context, solid-phase synthesis has been used primarily for the preparation of peptide and glycopeptide dendrimers [23]. For example, a second-generation dendrimer could be prepared by successive addition of branched polyproline building blocks to a solid phase [24]. The divergent synthesis of polyamide dendrimers on polystyrenes was accomplished [25] by Frechet el al. 1991 (cf. Fig. 2.8) [26]. PAMAM dendrons could be grown up to the fourth-... 

R462 J.-L. Reymond and T. Darbre, Peptide and Glycopeptide Dendrimer Apple Trees as Enzyme Models and for Biomedical Applications , Org. Biomol. Chem., [online computer file], 2012, 10, 1483. 

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