Butyric 2,4-dihydroxy-2-

PEROXIDES AND PEROXIDE COMPOUNDS - ORGANIC PEROXIDES] (Vol 18) llb,21-Dihydroxy-17-(l-oxobutoxy)-pregn-4-ene-3,20-dione. See Hydrocortisone butyrate. 

The interaction with both synthetic and naturally occurring amino acids has been studied extensively glycine (138, 173, 219-221), a-(173, 219) and /3-alanine (138, 220), sarcosine (219), serine (222), aspartic acid (138, 173, 222-226), asparagine (222), threonine (222), proline (219), hydroxyproline (219), glutamic acid (138, 222-225), glutamine (222), valine (219, 227), norvaline (219), methionine (222, 226), histidine (228, 229), isoleucine (219), leucine (219, 230), norleu-cine (219), lysine (222), arginine (222), histidine methyl ester (228), phenylalanine (138, 222), tyrosine (222), 2-amino-3-(3,4-dihydroxy-phenyl jpropanoic acid (DOPA) (222), tryptophan (222), aminoiso-butyric acid (219), 2-aminobutyric acid (219,231), citrulline (222), and ornithine (222). 

Dihydroxyacid dehydratase of the branched-chain amino acid biosynthetic pathway catalyzes the dehydration and tautomerization of 2,3-dihydroxy-3-methyl-(butyrate and pentanoate) to 2-keto-3-methyl(butyrate and pentanoate). The enzyme isolated from spinach recently has been shown to have not a [4Fe-4S] cluster, but rather a spectroscopically unusual [2Fe-2S] cluster in its active site (68,69). The EPR spectrum of the reduced enzyme is similar to that seen for Rieske Fe-S proteins (71) with a g-average of 1.91. Upon addition of substrate the g-average of the EPR spectrum shifts to 1.96 (opposite the effect of substrate on aconitase), and then reverts back to a g-average of 1.90 when only the product is present The dramatic changes in the EPR spectra upon addition of substrate suggest, in analogy to aconitase, that the Fe-S cluster may be directly involved in catalysis. 

Fiessdmann and Pfeiffer" passed HCl at 0° through acetoacetic ester and thioglycolic ester in dcohol to obtain triethyl y3, -bis(carbo-methoxymethylthio)butyrate (169) Dieckmann condensation reportedly furnish ethyl 3,4-dihydroxy-6a-methyl-3a,6a-dihydro-thieno(2,3-b]-thiophene-2-carbOxylate (170) [Eq. (48)]. 

HI - BUTYRIC ACID, 9-(2,9-DIHYDROXY-3,3-OIM6THYLBUTYRAMIDO)-, CALCIUM SALT, HYORATE (9 2 1)... 

Toda, F., and Tanaka, K. (1988) A New Chiral Host Compound 10,10 -Dihydroxy-9,9 -biphenanthryl. Optical Resolution of Propionic Acid Derivatives, Butyric Acid Derivatives, and 4-Hydroxycyclopent-2-en-l-one Derivatives by Complexation,... 

A solution of 1.0 g of 17-acetoxy-llfS,21-dihydroxy-6a-methyl-4-pregnene-3,20-dione in 20 ml of pyridine is combined with 3 ml of butyric anhydride and stirred at room temperature for 2 hours. The reaction solution is then allowed to flow into 150 ml of cooled 8% sulfuric acid and agitated for another... 

Chemical Name lip,17-Dihydroxy-21-mercaptopregn-4-ene-3,20-dione 17-butyrate... 

C27l IviFOjS 25092-18-6) see Clobctasone butyrate (6a, 1115,16ct)-6-fluoro-l 1,21 -dihydroxy-16-methylpregn-4-cnc-3,20-dione... 

Ap, 13.6Ap, 13.8Q,p Butyl acetate 10.4o Butylbicyclophosphorothioate 3.2Bn Butyl butyrate 10.4o Butyl-deoxygalactonojirimycin 13.1a Butyldesmethylibogaine 3.3Aa Butylheptylpyrrolidine 3.4An Butylidene-tetrahydro-dihydroxy-isobenzofuranone 4. lAp Butylphenyl-deoxyguanosine-triphosphate 9.3Dn... 

Hopantenate (calcium d-(+)-4-(2, 4-dihydroxy-3, 3-dimethylbutyramido)butyrate hemihydrate), or calcium hopantenate, is a homoanalog of 1-pantothenate and has been used in Japan for the treatment of mental retardation with behavioral abnormalities. It represents one of the many attempts that have been made, so far unsuccessfully, to develop derivatives of substances belonging to the vitamin B group as agents for the treatment of brain or nervous disorders (SEDA-12, 328) (SEDA-13, 347). 

Five-carbon Isosaccharinic Acid DL-[3-Deoxy-2-C- (hydroxymethyl)-tetronic acid], (dl-[2,4-dihydroxy -2- (hydroxymethyl) butyric ... 

The cream, ointment, and topical solution contain the topical corticosteroid hydrocortisone butyrate, a nonflu-orinated hydrocortisone ester. It has the chemical name pregn-4-ene-3,20-dione, 11,21 -dihydroxy-17- [(1 -oxobu-tyl)oxy-,(ll(beta))- the molecular formula is C25H3606 and the molecular weight is 432.54. Each gram of cream contains 1 mg hydrocortisone butyrate in a hydrophilic... 

Eritadenine. (R)-6-Amlno-a,ft-dihydrOxy-9H-purine-9-butnnoic acid 2(R),3(R)-dihydroxy-4-(9-adenyl)-butyric acid, (D-erythro-form) lentinacin lentysine. C,H, -N,04 mol wt 253.22. C 42.68%, H 4.38%, N 27.66%, O 25.27%. Isoln from the mushroom Lentinus edodes Sing. (Shiitake) and synthesis Chibata et al, Experientia 25, 1237 (1969). Syntheses Kamiya et al. Tetrahedron Letters 1969, 4729 eidem, Chem. Ind. 1970, 652 Okumura et al., Chem. Commun. 1970, 1045 Kawazu el al, ibid. 1970, 1047. Synthesis of D-threo- and L-threo-forms Hashimoto et of.. 

Benzenepropanamide, A/-[3-[[4-[[3- 3,4-dihydroxyphenyl)-1-oxo-2-propenyl]amino]butyr amino]propy 11-3,4-dihydroxy- 4249 ... 

Figure 8. Time course of appearance of cutinase as measured by immunochemical techniques (left) and cutinase activity as measured by -nitrophenyl butyrate hydrolysis (right) in the extracellular fluid of spore suspensions of F. solani f. sp. pisi induced with either cutin hydrolysate or purified Cie dihydroxy acid. (Reproduced with permission from Ref. 35. Copyright 1986 The National Academy of Sciences.)...

The D-enantiomer of 393 was obtained in an identical sequence of reactions starting frc m 2,3-0-isopropylidene-4-deoxy-D-threitol (395). This compound was prepared from L-threonine (394) in the following way the amino acid was deaminated to 25 3/ -dihydroxy-butyric acid. Esterification of the carboxyl group and protection of both hydroxyl groups with an isopropylidene grouping gave methyl 4-deoxy-2,3-0-isopropylidene-D-threonate. Reduction of the ester group afforded 395 smoothly. 

Butyraldoxime n-Butyraldoxime. Seem-Butyraldehyde oxime Butyramide, N,N -dithiobis (ethyleneiminocarbonylethylene)) bis (2,4-dihydroxy-3,3-dimethyl-, -(+)-. SeePantethine Butyrate sodium. See Sodium butyrate n-Butyric acid... 

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