Body sensations

The most common adverse reactions leading to discontinuation include device-related problems (eg, foreign body sensations, coital problems, device expulsion). 

Although side effects are usually mild, treatment with brimonidine tartrate includes oral dryness, ocular hyperemia, burning and stinging, headache, visual blurring, foreign body sensation, fatigue drowsiness, ovular allergic reactions, and ocular pruritus. 

Adverse reactions associated with use of the carbonic anyhydrase inhibitors include ocular burning, stinging, or discomfort immediately after administration, bitter taste, ocular allergic reaction, blurred vision, tearing, dryness, dermatitis, foreign body sensation, ocular discomfort, photophobia, and headache. 

Although mild, the adverse reactions associated with the mast cell inhibitors include headache, rhinitis, unpleasant taste, asthma, and cold/flu symptoms. These drug may also cause ocular burning or irritation, dry eye, eye redness, foreign body sensation, and ocular discomfort. 

Adverse reactions associated with administration of the corticosteroid ophthalmic preparations include elevated IOP with optic nerve damage, loss of visual acuity, cataract formation, delayed wound healing, secondary ocular infection, exacerbation of comeal infections, dry eyes, ptosis, blurred vision, discharge, ocular pain, foreign body sensation, and pruritus. 

The administration of die antiviral ophthalmics may cause occasional irritation, pain, pruritus, inflammation, or edema of the eyes or lids allergic reactions foreign body sensation photophobia and corneal clouding. 

Ocular eye involvement is common and may precede skin lesions. Ocular symptoms include foreign body sensation, burning or stinging, dryness, itching, ocular photosensitivity, teleangectasia, periorbital edema, chalazia (Fig. 17.8)... 

Local side effects include burning, stinging, itching, foreign body sensation, dry eyes, and conjunctivitis. Brinzolamide may have a lower incidence of these side effects since the drug is in a neutral pH solution. Dorzolamide has been reported to cause irreversible corneal decompensation. Taste abnormalities have been reported with each agent. Both topical carbonic anhydrase inhibitors are sulfonamides and are contraindicated in patients with history of sulfonamide hypersensitivity.10,13... 

Lodoxamide 1-2 drops in affected eye(s) four times daily Ocular stinging, foreign body sensation... 

Dry or foreign body sensation Mild itching Burning Stinging Photophobia... 

Chambless, D. L., Caputo, G. C., Bright, P., Gallagher, R. (1984). Assessment of fear of fear in agoraphobics The body sensations questionnaire and the agoraphobic cognitions questionnaire. Journal of Consulting and Clinical Psychology, 52, 1090-1097. 

The Neurophysiology Sensory Evoked Potentials test guideline (OPPTS 870.6855) is designed to detect and characterize changes in the sensory aspects of nervous system function that result from exposure to chemical substances. The techniques involve neurophysiological measurements from adult animals and are sensitive to changes in the function of auditory, somatosensory (body sensation), and visual sensory systems. 

Ophthalmic - Bimatoprost-associated ocular adverse events that occurred in 3% to 10% of patients, in descending order of incidence, included the following Ocular dryness, visual disturbances, ocular burning, foreign body sensation, eye pain, pigmentation of the periocular skin, blepharitis, cataract, superficial punctate keratitis, eyelid erythema, ocular irritation, eyelash darkening. 

Ophthalmic - Latanoprost-associated ocular adverse events reported at an incidence of 5% to 15% included the following Blurred vision, burning and stinging, conjunctival hyperemia, foreign body sensation, itching, increased pigmentation of the iris, punctate epithelial keratopathy. 

Adverse reactions occurring in at least 3% of patients include transient burning, stinging or discomfort upon instillation ocular itching/pruritus blurred vision dry eye tearing/discharge hyperemia crystalline deposits and foreign body sensation. 

Ciprofloxacin White crystalline precipitates lid margin crusting crystals/scales foreign body sensation itching conjunctival hyperemia bad taste in mouth corneal staining keratopathy/keratitis allergic reactions lid edema tearing photophobia corneal infiltrates nausea decreased vision. 

Ophthalmic- Local burning or discomfort, margin crusting, crystals or scales, foreign body sensation, ocular itching, altered taste Rare (less than 1 %)... 

Ocular itching, blurred vision, dry eye, tearing/discharge/foreign body sensation,... 

Ocular pain, pruritus, eye discomfort, decreased visual acuity, foreign body sensation Rare... 

Abnormal vision, eyelid disorder, foreign body sensation. 

A 15-year-old boy felt a foreign body sensation in his right eye after he had been raking hay. His local physician prescribed a suspension of tobramycin 0.3% + dexamethasone 0.1% tds, but 6 days later referred him for evaluation of a suspected fungal keratitis. He had a corneal epithelial defect with an underlying dense... 

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