Blood digestive tract

The filariform larva found in moist soils may be either ingested or penetrate the skin of its host. It is then carried through the circulatory system to the lungs and migrates up the respiratory tree into the digestive tract. The worms feed on intestinal tissue and blood. Some worms may persist in humans as long as nine years. Infestations cause cutaneous reactions, pulmonary lesions, intestinal ulcerations, and anemia. 

Fiber components are the principal energy source for colonic bacteria with a further contribution from digestive tract mucosal polysaccharides. Rate of fermentation varies with the chemical nature of the fiber components. Short-chain fatty acids generated by bacterial action are partiaUy absorbed through the colon waU and provide a supplementary energy source to the host. Therefore, dietary fiber is partiaUy caloric. The short-chain fatty acids also promote reabsorption of sodium and water from the colon and stimulate colonic blood flow and pancreatic secretions. Butyrate has added health benefits. Butyric acid is the preferred energy source for the colonocytes and has been shown to promote normal colonic epitheUal ceU differentiation. Butyric acid may inhibit colonic polyps and tumors. The relationships of intestinal microflora to health and disease have been reviewed (10). 

Curcumin possesses strong antioxidant capacities, which may explain its effects against degenerative diseases in which oxidative stress plays a major role. As previously described for flavonoids, it is unlikely that curcumin acts as a direct antioxidant outside the digestive tract since its concentration in peripheral blood and organs is very low (near or below 1 pM, even after acute or long-term supplementation). Indeed, it has been shown that the intestinal epithelium limits its entry into the body, as reflected by absorption studies in various models (portal blood perfusion, everted bags). ... 

The hepatic artery supplies the liver with 300 ml/min of oxygenated blood from the aorta. The remaining 1050 ml/min of blood flow is delivered by the hepatic portal vein. This blood comes directly from the digestive tract. It is low in oxygen but contains a high concentration of nutrients absorbed from the intestines. 

In terms of nutrients, the liver is the most important metabolic organ in the body. It receives a large volume of nutrient-rich blood directly from the digestive tract, which provides an abundant amount of substrates for metabolism. Metabolic processes involving carbohydrates include ... 

In addition to recurrent infection, CGD sufferers also exhibit abnormal inflammatory responses which include granuloma formation at various sites of the body (granuloma refers to a tissue outgrowth that is composed largely of blood vessels and connective tissue). This can lead to obstruction of various ducts, e.g. in the urinary and digestive tracts. 

At the crossroads between the digestive tract and the rest of the body resides the largest solid organ of the body the hver. Because of its interposition, the hver has a dual blood supply. 

Bithionol is absorbed to a limited degree from the digestive tract of the host and is detected in blood and particularly in the bile. Peak concentrations of bithionol are found in the bile within 2 h following treatment. Blood concentrations of the drug are significantly lower than those found in bile (6). 

Aside from its murky role in brain function, alpha-linolenic acid has some well-documented effects on heart disease. It reduces the risk of blood-clot formation, lowers the chance of potentially lethal irregular heartbeat, and probably has an antiinflammatory effect on blood vessels. Several studies have found a link between increased intake of the acid and reduced risk of death from heart disease. Alpha-linolenic acid helps lower blood cholesterol, but flaxseed has another component that performs this function even more effectively. This is soluble fiber, which isn t absorbed by the body and passes right through the digestive system. On its journey through the digestive tract, the fiber binds cholesterol and prevents it from... 

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