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Beta-peptides

Raguse, T. L., Lai, J. R., LePlae, P. R., and Gellman, S. H. Toward beta-peptide tertiary stmcture Self-association of an... [Pg.30]

Saudek V, Pivcova H, Drobnik J (1981) NMR-study of poly(aspartic acid). 2. Alpha-peptide and beta-peptide bonds in poly(aspartic acid) prepared by common methods. Biopolymers 20 1615-1623... [Pg.25]

Paris D, Ait-Ghezala G, Mathura VS, Patel N, Quadros A, Laporte V, et al. Anti-angiogenic activity of the mntant Dntch A(beta) peptide on human brain microvascular endothelial cells. Brain Res Mol Brain Res 2005 136 212-30. [Pg.163]

Gendelman HE, Persidsky Y (2005) Infections of the nervous system. Lancet Neurol 4 12-13 Gerard C, Rollins BJ (2001) Chemokines and disease. Nat Immunol 2 108-115 Gitter BD, Cox LM, Rydel RE, May PC (1995) Amyloid beta peptide potentiates cytokine secretion by interleukin-1 beta-activated human astrocytoma cells. Proc Natl Acad Sci USA 92 10738-10741 GiuUan D, Yu J, Li X, Tom D, Li J, Wendt E, Lin SN, Schwarcz R, Noonan C (1996) Study of receptor-mediated neurotoxins released by HIV-1-infected mononuclear phagocytes found in human brain. J Neurosci 16 3139-3153... [Pg.293]

Wilson DM, Binder LI. Free fatty acids stimulate the polymerization of tau and amyloid beta peptides. In vitro evidence for a common effector of pathogenesis in Alzheimer s disease. Am J Pathol 1997 150 2181-2195. [Pg.276]

Fraser PE, McLachlan DR, Surewicz WK, Mizzen CA, Snow AD, Nguyen JT, Kirschner DA. Conformation and fibrillogenesis of Alzheimer A beta peptides with selected substitution of charged residues. J Mol Biol 1994 244 64-73. [Pg.277]

Soto C, Castano EM, Kumar RA, Beavis RC, Frangione B. Fibrillogenesis of synthetic amyloid-beta peptides is dependent on their initial secondary structure. Neurosci Lett 1995 200 105-108. [Pg.277]

Soto C, Castano EM, Frangione B, Inestrosa NC. The alpha-helica to beta-strand transition in the amino-terminal fragment of the amyloid beta-peptide modulates amyloid formation. J Biol Chem 1995 270 3063-3067. [Pg.277]

Terenius L, Nordstedt C. Controlling amyloid beta-peptide fibril formation with protease-stable ligands. J Biol Chem 1997 272 12601-12605. [Pg.280]

Salomon AR, Marcinowski KJ, Friedland RP, Zagorski MG. Nicotine inhibits amyloid formation by the beta-peptide. Biochemistry 1996 35 13568-13578. [Pg.282]

Schmechel, D. E., Saunders, A. M., Strittmatter, W. J. et al. Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease. Proc. Natl Acad. Sci. U.S.A. 90 9649-9653, 1993. [Pg.664]

Haass, C. Take five—BACE and the gamma-secretase quartet conduct Alzheimer s amyloid beta-peptide generation. EMBO J. 23 483-488, 2004. [Pg.788]

Edbauer, D., Winkler, E., Haass, C. and Steiner, H. Presenilin and nicastrin regulate each other and determine amyloid beta- peptide production via complex formation. Proc. Natl Acad. Sci. USA 99 8666-8671, 2002. [Pg.789]

Li, R., Lindholm, K., Yang, L. B. et al. Amyloid beta peptide load is correlated with increased beta-secretase activity in sporadic Alzheimer s disease patients. Proc. Natl Acad. Sci. USA 101 3632-3637, 2004. [Pg.789]

Bard, F., Cannon, C., Barbour, R. et al. Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease. Nature Med. 6 916-919,2000. [Pg.789]

Nicoll, J. A., Wilkinson, D., Holmes, C. etal. Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide a case report. Nature Med. 9 448 452, 2003. [Pg.790]

Chambers RD, Fox MA, Sandford G (2005) Elemental fluorine - Part 18. Selective Direct Fluorination of 1,3-Ketoesters and 1,3-Diketones using Gas/ Liquid Microreactor Technology. Lab Chip 5 1132-1139 Cheng RP, Gellman SH, DeGrado WF (2001) Beta-Peptides From Structure to Function. Chem Rev 101 3219-3232... [Pg.16]

Flogel O, Codee JDC, Seebach D, Seeberger PH (2006) Microreactor Synthesis of Beta-Peptides. Angew Chem Int Ed 45 7000-7003 Geyer K, Codee JDC, Seeberger PH (2006) Microreactors as Tools for Synthetic Chemists - The Chemists Round-Bottomed Flask of the 21st Century Chem Eur J 12 8434-8442... [Pg.18]

Lelais G, Seebach D, Jaun B, Mathad RI, Flogel O, Rossi F, Campo M, Wort-mann A (2006) Beta-Peptidic Secondary Structures fortified and enforced by Zn2+ Complexation - On the Way to Beta-Peptidic Zinc Fingers Helv Chim Acta 89 361 103... [Pg.19]

Saaby S, Knudsen KR, Ladlow M, Ley SV (2005) The Use of a Continuous Flow-Reactor Employing a Mixed Flydrogen-Liquid Flow Stream for the Efficient Reduction of Imines to Amines. Chem Commun 23 2909-2911 Seebach D, Overhand M, Kilhnle FNM, Martinoni D, Oberer L, Hommel U, Widmer H (1996) Beta-Peptides Synthesis by Arndt-Eistert Homologation with Concomitant Peptide Coupling. Structure Determination by NMR and CD Spectroscopy and by X-ray Crystallography. Helical Secondary Structure of a Beta-Hexapeptide in Solution and its Stability Towards Pepsin. Helv Chim Acta 79 913-941... [Pg.20]

Watts P, Wiles C, Haswell SJ, Pombo-ViUar E, Styring P (2001) The Synthesis of Peptides Using Microreactors. Chem Comm 11 990-991 Watts P, Wiles C, Haswell S, Pombo-Villar E (2002a) Investigation of Racemi-sation in Peptide Synthesis within a Microreactor. Lab Chip 2 141-144 Watts P, Wiles C, Haswell S, Pombo-Villar E (2002b) Solution Phase Synthesis of Beta-Peptides Using Microreactors. Tetrahedron 58 5427-5439... [Pg.20]

Perutz, M. F., Pope, B. J., Owen, D., Wanker, E. E., and Scherzinger, E. (2002b). Aggregation of proteins with expanded glutamine and alanine repeats of the glutamine-rich and asparagine-rich domains of Sup35 and of the amyloid beta-peptide of amyloid plaques. Proc. Natl. Acad. Sci. USA 99, 5596-5600. [Pg.279]

Shanmugam, G., andjayakumar, R. (2004). Structural analysis of amyloid beta peptide fragment (25—35) in different microenvironments. Biopolymers 76, 421—134. [Pg.281]

Tjernberg, L. O., Callaway, D. J., Tjemberg, A., Hahne, S., Lilliehook, C., Terenius, L., Thyberg, J., and Nordstedt, C. (1999). A molecular model of Alzheimer amyloid beta-peptide fibril formation./ Biol. Chem. 274, 12619-12625. [Pg.281]

Dahlgren, K.N., Manelli, A.M., Stine, W.B., Jr., Baker, L.K., Krafft, G.A., and LaDu, M.J., Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability, J. Biol. Chem., 277, 32046, 2002. [Pg.239]

Puglielli, L., Konopka, G., Pack-Chung, E., Ingano, L.A., Berezovska, O., Hyman, B.T., Chang, T.Y., Tanzi, R.E., and Kovacs, D.M., Acyl-coenzyme A cholesterol acyltransferase modulates the generation of the amyloid beta-peptide, Nat. Cell Biol., 3, 905, 2001. [Pg.242]

Lahiri DK, Farlow MR, Sambamurti K. (1998). The secretion of amyloid beta-peptides is inhibited in the tacrine-treated human neuroblastoma cells. Brain Res Mol Brain Res. 62(2) 131-40. [Pg.479]

Yatin SM, Yatin M, Aulick T, Ain KB, Butterfield DA. (1999). Alzheimer s amyloid beta-peptide associated free radicals increase rat embryonic neuronal polyamine uptake and ornithine decarboxylase activity protective effect of vitamin E. Neurosci Lett. 263(1) 17-20. [Pg.493]

Several additional useful publications demonstrating practical applications of CE/MS methods for neurotransmitter analysis and neuropharmaceutical studies are those of Larsson and Lutz (2000) (neuropeptides including substance P) Hettiarachchi et al. (2001) (synthetic opioid peptides) Varesio et al. (2002) (amyloid-beta peptide) Zamfir and Peter-Katalinic (2004) (gangliosides) Peterson et al. (2002) (catecholamines and metanephrines) Cherkaoui and Veuthey (2002) (fluoxetine) and Smyth and Brooks (2004) (various lower molecular weight molecules including benzodiazepines, steroids, and cannabinols). [Pg.168]

Varesio E, Rudaz S, Krause KH, Veuthey JL. 2002. Nanoscale liquid chromatography and capillary electrophoresis coupled to electrospray mass spectrometry for the detection of amyloid-beta peptide related to Alzheimer s disease. [Pg.176]

MiravaUe, L., Tokuda, T., Chiarle, R., et al. (2000) Substitutions at codon 22 of Alzheimer s A-beta peptide induce diverse conformational changes and apoptotic effects in human cerebral endothelial cells. J. Biol. Chem., 275, 27110-27116. [Pg.331]

Gervais, F.G., Xu, D., Robertson, G.S., et al. (1999) Involvement of caspases in proteolytic cleavage of Alzheimer s amyloid-beta precursor protein and amyloidogenic A-beta peptide formation. Cell, 97, 395 06. [Pg.332]

Phiel, C.J., Wilson, C.A., Lee, V.M., Klein, P.S. (2003) GSK-3alpha regulates production of Alzheimer s disease amyloid-beta peptides. Nature, 423, 435-439. [Pg.332]

Oba, R., Igarashi, A., Kamata, M., Nagata, K., Takano, S., Nakagawa, H. (2005) The N-terminal active centre of human angiotensin-converting enzyme degrades Alzheimer amyloid beta-peptide. Eur. J. Neurosci., 21,133-740. [Pg.356]

Zhao H, Davies P, Marambaud P. (2005) Resveratrol promotes clearance of Alzheimer s disease amyloid-beta peptides. J Bio Chem 280 37377-37382. [Pg.397]

Qiu, W. Q. and Folstein, M. F. (2006). Insulin, insulin-degrading enzyme and amyloid-beta peptide inn Alzheimer s disease Review and hypothesis. Neurobiol. Aging 27,190-198. [Pg.148]

B7. Blasko, I., Wagner, M., Whitaker, N., Grubeck-Loebenstein, B., and Jansen-Durr, R, The amyloid beta peptide abeta (25-35) induces apoptosis independent of p53. FEES Lett. 470,221-225 (2000). [Pg.99]


See other pages where Beta-peptides is mentioned: [Pg.137]    [Pg.263]    [Pg.607]    [Pg.788]    [Pg.19]    [Pg.20]    [Pg.275]    [Pg.275]    [Pg.273]    [Pg.86]    [Pg.86]    [Pg.87]    [Pg.240]   
See also in sourсe #XX -- [ Pg.246 ]




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