Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Benzothiophene reactions

Figure 2. Induction Period - molten hydroxide treatment of benzothiophene (reaction temperature - 375°C). KOHrNaOH (60 40), ---o---- kOH, — —. Figure 2. Induction Period - molten hydroxide treatment of benzothiophene (reaction temperature - 375°C). KOHrNaOH (60 40), ---o---- kOH, — —.
Reaction of Dibenzothiophene. Dibenzothiophene was much less reactive than benzothiophene. Reactions in the standard KOH/NaOH mixture (60 40) at 375°C for 30 minutes in our laboratories demonstrated that dibenzothiophene was unreactive and quantitatively recovered. Using dibenzothiophene as a model, Maijgren and Hubner (18) observed that under similar reaction conditions (75 KOH and 25 NaOH, 370°C for 60 minutes), 81 of dibenzothiophene was recovered, but no reaction products were identified. Wallace et al. (J2) found also that dibenzothiophene was unreactive when heated at 200°C for 20 hours in a mixture of KOH and white oil. The severity of the reaction conditions in our laboratory was increased by raising the temperature to 400°C and allowing the reaction to occur for 6 hours. Under these conditions, using the standard KOH/NaOH mixture, dibenzothiophene reacted completely, producing approximately 62 o-phenylphenol and 6 biphenyl (approximately 30 of the material was unaccounted for). Apparently even dibenzothiophene will react with molten hydroxide and desulfurize if the reaction conditions are sufficiently severe. [Pg.67]

Thiophene-2-carbaldehyde, 3-bromo-synthesis, 4, 81 Thiophenecarbaldehydes benzothiophene synthesis from, 4, 906 reactions, 4, 807 synthesis, 4, 148 Wittig reactions, 4, 807 Thiophene-2-carb aldehydes bromination, 4, 753 conformation, 4, 33 halogenation, 4, 753 reactions, 4, 72-73 reactivity, 4, 72-73 reduction, 4, 776 Thiophene-3-carb aldehydes conformation, 4, 33 reactivity, 4, 72... [Pg.893]

Thiurets — see 1,2,4-Dithiazolidines, diimino-Thonzylamine antihistamine, 3, 153 Thorpe reaction benzothiophenes from, 4, 876 Thorpe-Ziegler cyclization, 2, 74 Three-membered heterocyclic compounds basicity, 7, 23... [Pg.896]

The only known reaction of a furan with a dihalocarbene is that recently reported between benzofuran and dichlorocarbene in hexane at 0°. The initial adduct (7) could not be isolated but on hydrolysis gave the ring-expanded product 8, possibly via 9, in 15% yield. Benzothiophene was recovered in 92% yield under the same conditions. 2,5-Dihydrofuran reacted with dichloro- and dibromo-carbene to give the products of allylic insertion, 2-dihalogenomethyl-2,5-dihydrofuran, as well as the normal addition products. ... [Pg.64]

Ring opening of the heteroring (C—S bond cleavage), 300, or even ring opening with elimination of the heteroatom, 301 and 302, happens in the reaction of benzothiophene with Ru3(CO)l2 (94AGE1381). [Pg.45]

A remarkable case of a Meerwein reaction of phenylacetylene was reported by Leardini et al. (1985) in a new synthetic route to benzothiophene derivatives. Aryldi-azonium salts with a thioether group in the 2-position add phenylacetylene and substituted phenylacetylenes in the presence of metallic copper or iodide ion in acetone, or of FeS04 in DMSO (Scheme 10-60). The radical 10.21 formed initially is attacked intramolecularly by the sulfur atom of the thioether group to give the benzothiophene 10.22 in high yields (55-95%) as shown in (Scheme 10-60). Lear-... [Pg.250]

Few 1 -benzothiophene-S-oxides 218 were obtained in moderate yields by treatment of 1-arylacetylenes 219 with sulfur dioxide and benzene in the presence of antimony pentafluoride250 (equation 127). A series of cyclic sulphoxides have been prepared by hydrolysis of the corresponding alkoxy sulphonium salts 220251-254 (equation 128). Syn-sulphoxide 221 was obtained in a low yield (15-20%) in the reaction of the dianion of cyclooctatetraene 222 with thionyl chloride255 (equation 129). [Pg.284]

Thiophenes continue to play a major role in commercial applications as well as basic research. In addition to its aromatic properties that make it a useful replacement for benzene in small molecule syntheses, thiophene is a key element in superconductors, photochemical switches and polymers. The presence of sulfur-containing components (especially thiophene and benzothiophene) in crude petroleum requires development of new catalysts to promote their removal (hydrodesulfurization, HDS) at refineries. Interspersed with these commercial applications, basic research on thiophene has continued to study its role in electrocyclic reactions, newer routes for its formation and substitution and new derivatives of therapeutic potential. New reports of selenophenes and tellurophenes continue to be modest in number. [Pg.77]

FIGURE 10.51 Transformation of benzothiophene involving microbial oxidation and chemical reaction of the sulfoxide. (From Neilson, A.H. and Allard, A.-S., The Handbook of Environmental Chemistry, Vol. 3J, pp. 1-80, Springer, Heidelberg, 1998. With permission.)... [Pg.567]

In addition, the formation of terminal metabolites may be adverse either for the organism itself, or for other organisms in the ecosystem. Microbial metabolites may also undergo purely chemical reactions to compounds that are terminal products. Examples include the formation of 5-hydroxyquinoline-2-carboxylate from 5-aminonaphthalene-2-sulfonate (Nortemann et al. 1993) or benzo[fc]naphtho[l,2- /]thiophene from benzothiophene (Kropp et al. 1994). Microbial metabolites may be toxic to both the bacteria producing them and to higher organisms. Illustrative examples of toxicity include the following ... [Pg.612]

The cracking of diphenylmethane (DPM) was carried out in a continuous-flow tubular reactor. The liquid feed contained 29.5 wt.% of DPM (Fluka, >99%), 70% of n-dodecane (Aldrich, >99% solvent) and 0.5% of benzothiophene (Aldrich, 95% source of H2S, to keep the catalyst sulfided during the reaction). The temperature was 673 K and the total pressure 50 bar. The liquid feed flow rate was 16.5 ml.h and the H2 flow rate 24 l.h (STP). The catalytic bed consisted of 1.0 g of catalyst diluted with enough carborundum (Prolabo, 0.34 mm) to reach a final volume of 4 cm. The effluent of the reactor was condensed at high pressure. Liquid samples were taken at regular intervals and analyzed by gas chromatography, using an Intersmat IGC 120 FL, equipped with a flame ionization detector and a capillary column (Alltech CP-Sil-SCB). [Pg.100]

This paper describes the successful incorporation of molybdenum and molybdenum-nickel clusters into zeolites with 12-membered ring by aqueous ion exchange and application of the resulting materials to HDS reaction of benzothiophene. Stoichiometry of the ion exchange was examined by elemental analysis. UV-visible spectroscopy and EXAFS measurements were carried out to investigate the structure of molybdenum species loaded on zeolites. [Pg.108]

The reaction of sulphides 59 bearing an ethynyl or a carbomethoxy group a to sulphur with f-butyl hypochlorite in methanol or ethanol gives high yields of the corresponding a-alkoxy sulphides (60) rather than sulphoxides (equation 29). Oxidation of benzo[b]thiophene with t-butyl hypochlorite in t-butyl alcohol at 30-40° gave the corresponding 2-chloro-l-benzothiophen-l-oxide 61 in 45% yield (equation 30). [Pg.249]

Scheme 1.26 Test reaction with dibenzothiophene or benzothiophene-oxazoline ligands. Scheme 1.26 Test reaction with dibenzothiophene or benzothiophene-oxazoline ligands.
Scheme 1.55 Test reaction with thiophene- and benzothiophene-oxazoline/ phosphine-containing ligands. Scheme 1.55 Test reaction with thiophene- and benzothiophene-oxazoline/ phosphine-containing ligands.

See other pages where Benzothiophene reactions is mentioned: [Pg.908]    [Pg.908]    [Pg.908]    [Pg.908]    [Pg.106]    [Pg.149]    [Pg.151]    [Pg.162]    [Pg.561]    [Pg.703]    [Pg.62]    [Pg.65]    [Pg.65]    [Pg.43]    [Pg.44]    [Pg.45]    [Pg.46]    [Pg.47]    [Pg.47]    [Pg.129]    [Pg.79]    [Pg.409]    [Pg.566]    [Pg.648]    [Pg.109]    [Pg.113]    [Pg.114]    [Pg.114]    [Pg.28]    [Pg.44]    [Pg.45]   
See also in sourсe #XX -- [ Pg.158 , Pg.159 , Pg.160 , Pg.161 , Pg.162 , Pg.163 , Pg.164 , Pg.165 , Pg.166 , Pg.167 , Pg.168 , Pg.169 , Pg.170 ]




SEARCH



1-Benzothiophen

Benzothiophene

Benzothiophene (cont reactions

Benzothiophene coupling reactions

Benzothiophenes

Benzothiophenes coupling reactions

Benzothiophens

Heteroaryl Heck reaction benzothiophene

Reactions of Thiophene and Benzothiophene

Reactions with Thiophene and Benzothiophene

Synthesis of Benzothiophenes via 4 1 Cycloaddition Reactions

Synthesis of Benzothiophens by Ring-closure Reactions

© 2024 chempedia.info