Bacillus anthracis. gram-positive

Among the bacilli, gram positive Bacillus anthracis, Corynebacterium diphtheriae, Clostridium species are highly sensitive. Among the spirochetes. Treponema pallidum is highly sensitive to penicillin. 

Endospore-forming gram-positive rods and cocci. Aerobic Bacillus (B. anthracis, anthrax), anaerobic Clostridium (C. tetani, tetanus C. botulinum, botulism)... 

Type Gram-positive bacilli Principal Features Generally rod-shaped retain color when treated by Gram s method of staining Common Examples Bacillus anthracis, Clostridium tetani... 

Daptomycin has proven efficacy in a number of in vivo animal models, including soft tissue infections by MRSA, bacteraemia caused by S. aureus or vancomycin-resistant enterococci (VRE), Enterococcus faecalis pyelonephritis, MRSA osteomyelitis, MRSA and Bacillus anthracis pulmonary infections, Gram-positive endocarditis, Clostridium difficile colitis and S. pneumoniae and S. aureus meningitis.9,64 66... 

The cell walls of Gram-positive bacteria, including the pathogens S. aureus. Bacillus anthracis. Streptococcus pneumoniae, and Enterococcus faecalis contain thick layers of peptidoglycan. The peptidoglycan layers serve as both a protective barrier and as a scaffold for the attachment of secondary cell wall polymers and surface proteins. Surface proteins include hydrolytic enzymes involved in peptidoglycan turnover, as well as structures such as pili... 

Bacillus cereus is a gram-positive, facultatively aerobic sporeformer whose spores do not swell the sporangium. These characteristics, along with specific biochemical features, are used to differentiate B. cereus from other species of the genus Bacillus (i.e., B. thuringoemsos and B. anthracis). The organism is widely distributed in nature and in food. It is commonly found in soil, milk, cereals, starches, herbs, spices, and other dried food stuffs. 

The antibacterial activity of 6-triazolylpenicillanic acids 113 (Figure 3.8) is reported against S. aureus ATCC 29213, E. coli ATCC 25922, Streptococcus pneumoniae ATCC 49619, and Bacillus anthracis AMES [87]. The compound 113 exhibited antibacterial activity against the Gram-positive strain S. pneumoniae with MIC value of4-8 4gml . The compound with a 2-biphenyl group side chain showed a moderated activity against B. anthracis (s 8 4g mh ). 

---