Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

B-cell progenitors

TCDD causes bone marrow hypocellularity, with specific decreases in the total number of hematopoietic stem cells (HSC) and lymphocyte precursors.42 16 Exposure to TCDD also diminishes mRNA levels of recombination activating gene-1 and terminal deoxy-nucleotidyl transferase in bone marrow cells.47 The best characterized effect of TCDD on bone marrow is the impaired maturation of B cells. A single dose of TCDD causes a transient, time- and dose-dependent, and developmental stage-specific impairment in B cell maturation, with mature B cells affected first, followed by depletion of B cell progenitors.45-46... [Pg.242]

B cell progenitor cells appear in bone marrow detectable in blood... [Pg.330]

IL-11 Bone marrow (stromal cells) B-cell progenitors and others Differentiation... [Pg.47]

Victor, K.D., Vu, K., Feeney, A.J. (1994). Limited junctional diversity in K light chains. Junctional sequences from CD43+B220+ early B cell progenitors resemble those from peripheral B cells. J. Immunol. 152,3467-3475. [Pg.93]

CXCR4 is widely expressed in different blood cell types including B-cells, T-cells, and monocytes (seeTable 4.1). In addition, expression of this receptor has been described in non-immune cells such as endothelial and epithelial cells (307). SDF-la was originally isolated from bone marrow stroma and it has been shown that it supports the proliferation on B-cell progenitors (310). Subsequent studies demonstrate that SDF-la is also a potent chemoattractant for lymphocytes and monocytes. Unlike other chemokines, SDF-la is constitu-tively expressed and is not regulated by proin-flammatory cytokines (307,311). [Pg.166]

Regulates early T cell progenitors, regulates early B cell progenitors,... [Pg.834]

Namen AE, Lupton S, Hjerrild K, et al. Stimulation of B-cell progenitors by cloned murine interleukin-7. Nature 1988 333 571-573. [Pg.278]

See other pages where B-cell progenitors is mentioned: [Pg.30]    [Pg.104]    [Pg.122]    [Pg.123]    [Pg.129]    [Pg.129]    [Pg.233]    [Pg.117]    [Pg.80]    [Pg.390]    [Pg.50]    [Pg.141]    [Pg.714]    [Pg.128]    [Pg.192]    [Pg.510]    [Pg.510]    [Pg.242]    [Pg.245]    [Pg.86]    [Pg.191]    [Pg.116]    [Pg.117]    [Pg.117]    [Pg.117]    [Pg.121]    [Pg.581]   
See also in sourсe #XX -- [ Pg.129 ]



SEARCH



B cells

© 2024 chempedia.info