Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

8-Azaguanine resistance

Skopek, T. R., H. L. Liber, J. J. Krolewski, and W. G. Thilly, Quantitative Forward Mutation Assay in Salmonella typhimurium Using 8-Azaguanine Resistance as a Genetic Marker, Proc. Natl. Acad. Sci. U.S.A., 75, 410-414 (1978b). [Pg.543]

Liber, H.L. (1985) Mntation tests with Salmonella nsing 8-azaguanine resistance as the genetic marker. Prog. Mutat. Res., 5, 213-216... [Pg.137]

Skopek, T.R., Andon, B.M., Kaden, D.A. Thilly, W.G. (1981) Mutagenic activity of 42 coded compounds using 8-azaguanine resistance as a genetic marker in Salmonella typhimurium. In de Serres, F.J. Ashby, J., eds. Progress in Mutation Research, Vol. 1, Evaluation of Short-Term Tests for Carcinogens. Report of the International Collaborative Program, Amsterdam, Elsevier/North-Holland, pp. 371-375... [Pg.381]

Salmonella typhimurium TM35 his — Forward mutation 8-azaguanine resistance... [Pg.84]

As an alternative to the much-used Ames test for mutagenicity, forward mutation to 8-azaguanine resistance is being used as a more positive, and equally sensitive, alternative to the usual reverse mutation to histidine utili-zation. ... [Pg.176]

Azaguanine-resistant avian sarcoma virus-infected cells were less tu-morigenic than nonresistant cells in hamsters. Incubation of cells (infected with adenoviruses in tissue culture) with 8-azaguanine (10 M) inhibited reproduction of the virus. At this concentration, the drug was not toxic for healthy mammalian cells. ... [Pg.178]

Skopek TR, Andon BM, Kaden DA, et al. 1981. Mutagenic activity of 42 coded compounds using 8-azaguanine resistance as a genetic marker in Salmonella typhimurium. In deSerres FJ, Ashby J, eds. [Pg.135]

Ishii, K. and Shiio, I. (1972) Improved inosine production and derepression of purine nucleotide biosynthetic enzymes in 8-azaguanine resistant mutants of Bacillus subtilis. Agric. Biol. Chem.,... [Pg.293]

Table 1. Influence of inhibition of poly(ADP-ribose) polymerase on MNNG X-ray and UV-induced 8-azaguanine resistant mutant in V79 cells... Table 1. Influence of inhibition of poly(ADP-ribose) polymerase on MNNG X-ray and UV-induced 8-azaguanine resistant mutant in V79 cells...
NSO, non-lg secreting, non-L-chain synthesizing. 8-Azaguanine-resistant and HAT-sensitive mouse myeloma cell line... [Pg.373]

The ultimate goal of any short-term test system is to identify compounds that cause mutations or cancer in man. The experimental approach adopted by Carrano et indicates that SCE may have a close relationship to mutation to 8-azaguanine resistance in cultured Chinese hamster cells, but any attempt to correlate the results of the SCE test either with data on animal carcinogenicity or with the results of other test systems is hampered by the comparatively small number of chemicals that have been investigated rigorously, i.e., those for which a least-effective concentration can be estimated, and by the current variations in test protocol among laboratories. [Pg.32]

G. M. Williams, C. Tong, and J. J. Berman, Characterization of analog resistance and purine metabolism of adult rat-liver epithelial cell 8-azaguanine-resistant mutants, Mutat. Res. 49, 103-115 (1978). [Pg.78]

C. F. Arlett and S. A. Harcourt, The induction of 8 azaguanine-resistant mutants in cultured Chinese hamster cells by ultraviolet light. The effect of changes in post-irradiation conditions, Mutat. Res. 14, 431 (1972). [Pg.361]

F. D. Gillin, D. J. Roufa, A. L. Beaudet, and C. T. Caskey, 8-Azaguanine resistance in mammalian cells. I. Hypoxanthine-guanine phosphoribosyltransferase. Genetics 72, 239... [Pg.362]

J. E. Lever, G. Nuki, and J. E. Seegmiller, Expression of purine overproduction in a series of 8-azaguanine-resistant diploid human lymphoblast lines, Proc. Natl. Acad. Sci. (U.S.A.) 71, 2679 (1974). [Pg.362]

Mutation from 8-azaguanine sensitivity to 8-azaguanine resistance (30 ig/ml). From Chu et at. (1969). [Pg.92]

BIOCHEMICAL CHARACTERISTICS OF 8-AZAGUANINE RESISTANT HUMAN LYMPHOBLAST MUTANTS SELECTED IN VITRO... [Pg.255]

H7P0XANTHIME-GUANINE-PH0SPH0RIB0SYLTRANSFERASE ACTIVITY IN CLONED 8-AZAGUANINE RESISTANT HUHAN LYMPHOBLASTS... [Pg.258]

See other pages where 8-Azaguanine resistance is mentioned: [Pg.246]    [Pg.19]    [Pg.20]    [Pg.322]    [Pg.322]    [Pg.323]    [Pg.318]    [Pg.371]    [Pg.233]    [Pg.61]    [Pg.167]    [Pg.261]    [Pg.379]    [Pg.12]    [Pg.12]    [Pg.258]    [Pg.259]    [Pg.260]   
See also in sourсe #XX -- [ Pg.18 , Pg.19 ]

See also in sourсe #XX -- [ Pg.337 ]

See also in sourсe #XX -- [ Pg.230 ]



SEARCH



8-Azaguanine

8-Azaguanine cell resistance

8-Azaguanine human lymphoblast resistant

© 2024 chempedia.info