Anopheles gambiae

Normal Routes of Exposure Vectors (mosquitoes—Anopheles funestus, Anopheles gambiae). Infectious Dose Unknown. 

Many hunters react to their prey s overall scent or some of its components, perhaps the smell of fur or some less complex odor. One of the world s most injurious insects, the African malaria mosquito (Anopheles gambiae), prefers humans to other sources of a blood meal. Oddly, whenever possible the mosquitoes bite people on their feet. This predilection reflects their strong attraction to the mixture of fatty acids that we associate with smelly feet. Humans may find the odor offensive, but these mosquitoes know it as a fragrant guide to blood. The same fatty acids also draw them to another odor that offends some people, the smell of Limburger cheese. 

V. L. Schramm, Anopheles gambiae purine nucleoside phosphorylase Catalysis, structure, and inhibition, Biochemistry, 46 (2007) 12405—12415. 

Mans, B.J. et al. (2007) The crystal structure of D7r4, a salivary biogenic amine-binding protein from the malaria mosquito anopheles gambiae. J. Biol. Chem., 282 (50), 36626-36633. 

Fox A. N., Pitts R. J. and Zwiebel L. J. (2002) A cluster of candidate odorant receptors from the malaria vector mosquito, Anopheles gambiae. Chem. Senses 27, 453 459. 

Grossman G. L., Rafferty C. S., Clayton J. R., Stevens T. K., Mukabayire O. and Benedicte M. Q. (2001) Germline transformation of the malaria vector Anopheles gambiae, with the piggyBac transposable element. Insect Molecular Biology 10, 597-604. 

Jones M. D., Hill M. and Hope A. M. (1967) The circadian flight activity of the mosquito Anopheles gambiae phase setting by the light regime. J. Exp. Biol. 47, 503-511. 

Sun X. J., Tolbert L. P. and Hildebrand J. G. (1997) Synaptic organization of the uniglomerular projection neurons of the antennal lobe of the moth Manduca sexta a laser scanning confocal and electron microscopic study. J. Comp. Neurol. 379, 2-20. Takken W., van Loon J. J. A. and Adam W. (2001) Inhibition of host-seeking response and olfactory responsiveness in Anopheles gambiae following blood feeding. J. Insect. Physiol. 47, 303-310. 

Biessmann H., Walter M. F., Dimitratos S. and Woods D. (2002) Isolation of cDNA clones encoding putative odourant binding proteins from the antennae of the malaria-transmitting mosquito, Anopheles gambiae. Insect Mol. Biol. 11, 123-132. 

Vogt R. G. (2002) Odorant binding proteins of the malaria mosquito Anopheles gambiae possible orthologues of the OS-E and OS-F OBPs of Drosophila melanogaster. J. Chem. Ecol. 28, RC29-RC35 (http //www.kluweronline.com/issn/0098-0331)... 

Area B., Lombardo F, Lanfrancotti A., Spanos L., Veneri M., Louis C. and Coluzzi M. (2002) A cluster of four D7-related genes is expressed in the salivary glands of the African malaria vector Anopheles gambiae. Insect Mol. Biol. 11, 47-55. 

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