Proteins odorant-binding

In the posterior glands of the nasal septum and in the vomeronasal glands an odorant-binding protein (OBP-II), as expected, increases... 

Bianchet M., Bains G., Pelosi P., Pevsner J., et al. (1996). The three-dimensional structure of bovine odorant binding protein and its mechanism of odour recognition. Nature Struct Biol 3, 934-939. 

Krishna N., Getchell M., Margolis F. and Getchell T. (1995). Differential expression of vomeromodulin and odorant-binding protein, putative pheromone and odorant transporters, in the developing rat nasal chemosensory mucosae. J Neurosci Res 40, 54-71. 

Lobel D., Marchese S., Krieger J., Pelosi P., et al. (1998). Subtypes of odorant-binding proteins heterologous expression and ligand binding. Europ J Biochem 254, 318-324. 

Spielman A., Zeng X., Leyden J. and Preti G. (1995). Proteinaceous precursors of human axillary odor — isolation of two novel odorant binding proteins. Experientia 51, 40-47. 

Tegoni M., Pelosi P., Vincent F., Spinelli S., et al. (2000). Mammalian odorant binding proteins. Biochim Biophys Acta 1482, 229-240. 

Lazar, J., Greenwood, D.R., Rasmussen, L.E.L. and Prestwich, G.D. (2002) Molecular and functional characterization of an odorant binding protein of the Asian elephant, Elephas maximas Implications for the role of lipocalins in mammalian olfaction. Biochemistry 41, 11786-11794. 

Keywords Odorant-binding proteins Odorant-degrading enzymes ... 

Using a specific antibody, Shanbhag and collaborators [34] demonstrated that LUSH is expressed in sensilla trichodea of the Drosophila antennae along with two other putative odorant-binding proteins Obp83a (PBPRP-3, OS-F) and Obp83b (OS-E). When antennal sections of the LUSH-deficient mutant were la-... 

Fig. 9 Alignment of the amino acid sequences of pheromone-binding proteins from the silkworm moth B. mori and the cockroach L. maderae, BmorPBP and LmadPBP,respectively and a putative odorant-binding protein from D. melanogaster, LUSH. In LmadPBP and LUSH the N-terminal sequence of the mature proteins were predicted by cleaving signal peptides in silico [28,79], whereas in BmorPBP this was confirmed by the sequence of the isolated protein [38]...

There has been no research reported on the interaction of periplanones with pheromone-binding proteins or dendritic receptors. Nevertheless, two studies, one empirical and one theoretical, report on intrasensillar events in P. americana. Picim-bon and Leal (1999) determined the N-terminal amino acid sequences of two soluble proteins (putative odorant-binding proteins) that are specifically expressed in male antennae, and several other proteins that are expressed in antennae of both males... 

Bohbot J., Sobrio F., Lucas P. and Nagnan-Le Meillour P. (1998) Functional characterization of a new class of odorant-binding proteins in the moth Mamestra brassicae. Biochem Biophys. Res. Commun. 253, 489—494. 

Briand L., Nespoulous C., Huet J. C., Takahashi M. and Pernollet J. C. (2001) Ligand binding and physico-chemical properties of ASP2, a recombinant odorant-binding protein from honeybee (Apis mellifera L.). Eur. J. Biochem. 268, 752-760. 

Kim M. S., Repp A. and Smith D. P. (1998) LUSH odorant-binding protein mediates chemosensory responses to alcohols in Drosophila melanogaster. Genetics 150, 711-721. 

Pikielny C. W., Hasan G., Rouyer F. and Rosbash M. (1994). Members of a Family of drosophila putative odorant-binding proteins are expressed in different subsets of olfactory hairs. Neuron 12, 35 -9. 

The biochemistry of odor detection involves at least three types of protein odor receptors (ORs) odorant binding proteins (OBPs) and odor degrading enzymes (ODEs). ORs are expressed by olfactory receptor neurons (ORNs) and localized in the membranes of the ciliated dendrites (Figure 14.1). The result of detection is translated into neuronal electrical activity by transductory proteins. But while transductory proteins are more or less common for all olfactory neurons, differential expression of ORs, OBPs and ODEs allows the neurons to detect specific odor molecules. 

---