Androgen synthetic

Ancymidol, 13 40t, 306 Anderson and McLean experimental design text, versus other texts, 8 395t Andgemifloxacin, 21 222 Andreason sedimentation pipette, 8 720 Andreev reflection, 23 821 Androgens, synthetic, 13 3 Anemia... 

NaturaHy occurring and synthetic estrogens and androgens have been extensively and safely used to improve efficiency and carcass composition ia growing beef catde in the United States since the early 1950s. Several anaboHc steroid implants have been approved for use in beef catde in the United States, but only one, zeranol [55331-29-8] is approved for use in lambs. Anabolic steroids are not used for growth regulation in swine or poultry (see Steroids). 

Female sexual development and behaviour in mammals occurs by default and requires no ovarian secretion, and it is only in genetic males that the testis can secrete hormones which destroy this female pattern and superimpose that of the male. Sexual differentiation is not so well defined in fish, and larval exposure to both synthetic estrogens and androgens is widely used in aquaculture to produce monosex cultures. Endocrine disruption of sexual differentiation in fish may therefore reflect both the complexity and diversity of such processes between different species. Some care is required in use of the terms hermaphrodite and sex-reversal since a true hermaphrodite has both functional testes and ovaries and a sex-reversed fish is fully functional as its final sex—both produce the appropriate viable gametes. Such functional sex-reversal is not possible in mammals, but in some species of fish it is the normal developmental pattern. In most of the cases of hermaphroditism or sex-reversal reported in the non-scientific press, there is evidence only for a few ovarian follicles within a functional testis. This may be considered as feminisation or a form of intersex, and is very clearly endocrine disruption, but it is certainly neither sex-reversal nor hermaphroditism. In some cases the terms have even been used to infer induction of a single female characteristic such as production of yolk-protein by males. 

The pharmaceutical industry has developed and studied a number of anabolic steroids for use in veterinary medicine and in rehabilitation from injuries that are accompanied by deterioration of muscles. The ideal agent would be one that possessed the anabolic properties of testosterone without its androgenic (masculinizing) effects. Methandrostenolone (Dianabol) and stanozolol are among the many synthetic anabolic steroids that require a prescription. 

The anabolic steroids are synthetic dragp chemically related to the androgens. Like the androgens, they promote tissue-building processes. Given in normal doses,... 

Elaboration of a commercially viable route for total synthesis of 19-nor steroids led to the introduction of the totally synthetic product norgestrel (71) as the progestational component of an oral contraceptive. As was observed in the "natural" 19-nor-compounds, reduction of the 17-ethynyl group to 17-ethyl affords compounds with androgenic/anabolic... 

A 25-year-old male with hypogonadism is treated with a synthetic androgen. Which of the following is activated by a synthetic androgen ... 

Scheme 1.34 Lipase resolution of a key intermediate in the synthetic route to an androgen receptor antagonist. TBME tert-butyl methyl ether...

The term androgens includes a number of natural and synthetic compounds that exhibit the masculinizing and anabolic action of testosterone, the main physiological, endogenic, and androgenic hormone. 

In applied medicine, testosterone esters (propionate, cypionate, and enantate) and a synthetic analog, methyltestosterone, are widely used. In many tissues, testosterone s androgenic... 

Oral Testosterone is metabolized by the gut and 44% is cleared by the liver in the first pass. The synthetic androgens are less extensively metabolized by the liver and have longer half-lives and are more suitable than testosterone for oral administration. 

Pharmacology A synthetic androgen derived from ethisterone, danazol suppresses the pituitary-ovarian axis by inhibiting the output of pituitary gonadotropins. Danazol depresses the output of both follicle-stimulating hormone (FSH) and luteinizing... 

Danazol Synthetic androgen. Suppresses gonadotrophin production. Exhibits some weak androgenic activity Oral administration in the treatment of endometriosis, benign breast disorders, menorrhagia, premenstrual syndrome and hereditary angioedema... 

Methyltestosterone Synthetic androgen, longer circulatory half-life than testosterone Replacement therapy for male hypogonadal disorders. Breast cancer in females... 

Stanozolol Synthetic androgen Treatment of some clinical presentations of Behfet s syndrome and management of hereditary angioedema... 

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