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Alveolar epithelial cells

Figure 14 Observed permeability coefficients of urea and mannitol across monolayers of rat alveolar epithelial cells in primary culture in the Transwell system are correlated with transepithelial electrical resistance and days in culture. Figure 14 Observed permeability coefficients of urea and mannitol across monolayers of rat alveolar epithelial cells in primary culture in the Transwell system are correlated with transepithelial electrical resistance and days in culture.
Figure 16 Correlation of effective pore radius of the paracellular route of rat alveolar epithelial cell monolayers with transepithelial electrical resistance and time in culture. Pore radii were calculated from the data shown in Figure 14. Figure 16 Correlation of effective pore radius of the paracellular route of rat alveolar epithelial cell monolayers with transepithelial electrical resistance and time in culture. Pore radii were calculated from the data shown in Figure 14.
Elfinger M, Pfeifer C, Uezguen S, Golas MM, Sander B, Maucksch C, Stark H, Aneja MK, Rudolph C (2009) Self-assembly of ternary insulin-polyethylenimine (PEI)-DNA nanoparticles for enhanced gene delivery and expression in alveolar epithelial cells. Biomacromolecules 10 2912-2920... [Pg.26]

Calcium oxalate monohydrate responsible for the formation of most kidney stones significantly increased mitochondrial superoxide production in renal epithelial cells [42], Recombinant human interleukin IL-(3 induced oxygen radical generation in alveolar epithelial cells, which was suppressed by mitochondrial inhibitors 4 -hydroxy-3 -methoxyacetophe-none and diphenylene iodonium [43]. Espositio et al. [44] found that mitochondrial oxygen radical formation depended on the expression of adenine nucleotide translocator Anti. Correspondingly, mitochondria from skeletal muscle, heart, and brain from the Antl-deficient mice sharply increased the production of hydrogen peroxide. [Pg.752]

Colquhoun and Schumacher [98] have shown that y-linolcnic acid and eicosapentaenoic acid, which inhibit Walker tumor growth in vivo, decreased proliferation and apoptotic index in these cells. Development of apoptosis was characterized by the enhancement of the formation of reactive oxygen species and products of lipid peroxidation and was accompanied by a decrease in the activities of mitochondrial complexes I, III, and IV, and the release of cytochrome c and caspase 3-like activation of DNA fragmentation. Earlier, a similar apoptotic mechanism of antitumor activity has been shown for the flavonoid quercetin [99], Kamp et al. [100] suggested that the asbestos-induced apoptosis in alveolar epithelial cells was mediated by iron-derived oxygen species, although authors did not hypothesize about the nature of these species (hydroxyl radicals, hydrogen peroxide, or iron complexes ). [Pg.756]

Elbert KJ, Schafer UF, Schafers HJ, Kim KJ, Lee VHL, Lehr C-M (1999) Mono-layers of human alveolar epithelial cells in primary cultures for pulmonary drug delivery and transport studies. Pharm Res 16 601-608. [Pg.156]

Matsukawa Y, Lee VHL, Crandall ED, Kim K-J (1997) Size-dependent dextran transport across rat alveolar epithelial cell monolayers. J Pharm Sci 86 305-309. [Pg.159]

ACE Angiotensin-converting enzyme AEC Alveolar epithelial cell... [Pg.258]

Alveolar epithelial cells (AECs) are connected with each other by various epithelial cell-cell contacts (i.e., tight junctions, adherens junctions and others). These contacts comprise several groups of proteins, such as occludin, zonula occludens (ZO-1, -2, -3), claudins, tricellulin, E-cadherin and intercellular adhesion molecule-1 (ICAM-1) [13-15], Their regulation and interplay, which has influence on epithelial barrier properties, however, is largely unknown to date. [Pg.261]

Figure 11.2 Morphological differences between human alveolar epithelial cells in primary culture (A and C) and the A549 cell line (B and D). Cells are visualised by light microscopy (A and B) and immunofluorescence microscopy (C and D) using an antibody against a tight junctional protein, occludin. Figure 11.2 Morphological differences between human alveolar epithelial cells in primary culture (A and C) and the A549 cell line (B and D). Cells are visualised by light microscopy (A and B) and immunofluorescence microscopy (C and D) using an antibody against a tight junctional protein, occludin.
Primary Alveolar Epithelial Cell Culture Models... [Pg.268]

Table 11.3 Summary of the Expression Pattern and Activities of Phase I and Phase II Metabolic Enzymes and Various Peptidases/Proteases in Human Peripheral Lung Tissues, Primary Rat AEC Culture and Human Alveolar Epithelial Cell Line, A549. Table 11.3 Summary of the Expression Pattern and Activities of Phase I and Phase II Metabolic Enzymes and Various Peptidases/Proteases in Human Peripheral Lung Tissues, Primary Rat AEC Culture and Human Alveolar Epithelial Cell Line, A549.
Chen SP, Zhou B, Willis BC, Sandoval AJ, Liebler JM, Kim KJ, Ann DK, Crandall ED, Borok Z (2005) Effects of transdifferentiation and EGF on claudin isoform expression in alveolar epithelial cells. J Appl Physiol 98(1) 322-328... [Pg.275]

Madjdpour C, Oertli B, Ziegler U, Bonvini JM, Pasch T, Beck-Schimmer B (2000) Lipopolysaccharide induces functional ICAM-1 expression in rat alveolar epithelial cells in vitro. Am J Physiol 278(3) L572-L579... [Pg.275]

Cavanaugh KJ Jr, Oswari J, Margulies SS (2001) Role of stretch on tight junction structure in alveolar epithelial cells. Am J Respir Cell Mol Biol 25(5) 584—591... [Pg.276]

Dobbs LG, Gonzalez R, Matthay MA, Carter EP, Allen L, Verkman AS (1998) Highly water-permeable type I alveolar epithelial cells confer high water permeability between the airspace and vasculature in rat lung. Proc Natl Acad Sci USA 95(6) 2991-2996... [Pg.276]

Paine R 3rd, Christensen P, Toews GB, Simon RH (1994) Regulation of alveolar epithelial cell ICAM-1 expression by cell shape and cell-cell interactions. Am J Physiol 266(4 Pt 1) L476-L484... [Pg.277]

Herold S, von Wulffen W, Steinmueller M, Pleschka S, Kuziel WA, Mack M, Srivastava M, Seeger W, Maus UA, Lohmeyer J (2006) Alveolar epithelial cells direct monocyte transepithelial migration upon influenza virus infection impact of chemokines and adhesion molecules. J Immunol 177(3) 1817-1824... [Pg.277]

Fuchs S, Hollins AJ, Laue M, Schaefer UF, Roemer K, Gumbleton M, Lehr CM (2003) Differentiation of human alveolar epithelial cells in primary culture— Morphological characterisation and expression of caveolin-1 and surfactant protein-C. Cell Tissue Res 311 31-45... [Pg.278]

Wang J, Edeen K, Manzer R, Chang Y, Wang S, Chen X, Funk CJ, Cosgrove GP, Fang X, Mason RJ (2007) Differentiated human alveolar epithelial cells and reversibility of their phenotype in vitro. Am J Respir Cell Mol Biol [Epub ahead of print] doi 10.1165/rcmb.2006-04100C... [Pg.278]

Lieber M, Smith B, Szakal A, Nelson-Rees W, Todaro G (1976) A continuous tumor-cell line from a human lung carcinoma with properties of type II alveolar epithelial cells. Int J Cancer 17(1 ) 62—70... [Pg.278]

Forbes B, Wilson CG, Gumbleton M (1999) Temporal dependence of ectopepti-dase expression in alveolar epithelial cell culture implications for study of peptide absorption. Int J Pharm 180(2) 225-234... [Pg.278]

Newton DA, Rao KM, Dluhy RA, Baatz JE (2006) Hemoglobin is expressed by alveolar epithelial cells. J Biol Chem 281 (9) 5668—5676... [Pg.279]

Koslowski R, Barth K, Augstein A, Tschernig T, Bargsten G, Aufderheide M, Kasper M (2004) A new rat type I-like alveolar epithelial cell line R3/1 bleomycin effects on caveolin expression. Histochem Cell Biol 121 (6) 509—519... [Pg.279]

Goodman BE, Crandall ED (1982) Dome formation in primary cultured mono-layers of alveolar epithelial cells. Am J Physiol 243 C96-C100... [Pg.279]

Shen J, Elbert KJ, Yamashita F, Lehr CM, Kim KJ, Lee VH (1999) Organic cation transport in rabbit alveolar epithelial cell monolayers. Pharm Res 16(8) 1280-1287... [Pg.279]

Steimer A, Franke H, Haltner-Ukomado E, Laue M, Ehrhardt C, Lehr CM (2007) Monolayers of porcine alveolar epithelial cells in primary culture as an in vitro model for drug absorption studies. Eur J Pharm Biopharm [Epub ahead of print] doi 10.1016/j.ejpb.2006.11.006... [Pg.279]

Ehrhardt C, Kim KJ, Lehr CM (2005) Isolation and culture of human alveolar epithelial cells. Methods Mol Med 107 207-216... [Pg.279]

Cheek JM, Kim KJ, Crandall ED (1989) Tight monolayers of rat alveolar epithelial cells bioelectric properties and active sodium transport. Am J Physiol 256 (3 Pt 1 ) C688-C693... [Pg.279]


See other pages where Alveolar epithelial cells is mentioned: [Pg.304]    [Pg.304]    [Pg.310]    [Pg.275]    [Pg.7]    [Pg.1164]    [Pg.221]    [Pg.73]    [Pg.74]    [Pg.138]    [Pg.145]    [Pg.243]    [Pg.259]    [Pg.261]    [Pg.266]    [Pg.267]    [Pg.269]   
See also in sourсe #XX -- [ Pg.177 ]

See also in sourсe #XX -- [ Pg.196 ]

See also in sourсe #XX -- [ Pg.401 ]




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Alveolar

Alveolar cells

Alveolar clearance epithelial cell line

Alveolar epithelial cells barrier properties

Alveolar epithelial cells primary models

Alveolar epithelial cells surface area

Alveolar epithelial type I cells

Alveolar epithelial type II cells

Epithelial

Epithelial cells

Epithelialization

Human alveolar epithelial cells

The Use of Alveolar Epithelial Cells in Biopharmaceutical Research

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