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Alpha-ketoglutarate

Diaz, F. and Komuniecki, R.W. (1996) Characterization of the alpha-ketoglutarate dehydrogenase complex from Fasciola hepatica potential implications for the role of calcium in the regulation of helminth mitochondrial metabolism. Molecular and Biochemical Parasitology 81,243—246. [Pg.288]

KCN, 10 mg/kg BW Loss of consciousness in 100% blood ammonia levels increased 2.5X brain amino acid levels (i.e., leucine, isoleucine, tyrosine, phenylalanine) increased by 1.5-3.0X. Alpha ketoglutarate, at 500 mg/kg BW by intraperitoneal injection, completely blocked the development of cyanide-induced loss of consciousness and hyperammonemia 19... [Pg.947]

Hume AS, Mozigo JR, McIntyre B, et al. 1995. Antidotal efficacy of alpha-ketoglutaric acid and sodium thiosulfate in cyanide poisoning. Clinical Toxicol 33(6) 721-724. [Pg.254]

Hausinger, R.P. (2004) Fe(ll)/alpha-Ketoglutarate-Dependent Hydroxylases and Related Fnzymes. Critical Reviews in Biochemistry and Molecular Biology,... [Pg.287]

Figure 1. Total ion current of n-butyl esters of the acidic fraction from non-sterile leaf washings of C. sativa. Key 1 = oxalic acid 2 = malonic acid 3 = maleic acid 4 = succinic acid 5 = fumaric acid 6 = alpha-ketoglutaric acid 7 = cis-aconitic acid 8 = citric acid (19)-... Figure 1. Total ion current of n-butyl esters of the acidic fraction from non-sterile leaf washings of C. sativa. Key 1 = oxalic acid 2 = malonic acid 3 = maleic acid 4 = succinic acid 5 = fumaric acid 6 = alpha-ketoglutaric acid 7 = cis-aconitic acid 8 = citric acid (19)-...
Krebs cycle Inhibition of aconitase by superoxide and fluoroacetate, of succinate dehydrogenase by methamphetamine and mal-onate, of alpha-ketoglutarate dehydrogenase by salicylic add... [Pg.334]

Thiamine (vitamin Bi) is phosphorylated by ATP to thiamine pyrophosphate. This is a coenzyme for, among others, alpha-ketoglutarate dehydrogenase, transketolase and pyruvate dehydrogenase. Thiamine pyrophosphate is involved in fatty acid... [Pg.473]

Phyllanthus simplex Ketziu Dan Ye Xiz Zhu (leaf) Alpha-ketoglutaric acid, simplexine.57-211 212 Treat sore eyes, hepatitis, mammary gland infection. [Pg.125]

Dogra, J. V. V. and S. . P. Sinha. 1979. Observation of the age related changes in the level of alpha-ketoglutaric acid in leaves of Phyllanthus simplex (Retz.). Comp. Physiol. Ecol. 4 35-37. [Pg.320]

Since in the citric acid cycle there is no net production of its intermediates, mechanisms must be available for their continual production. In the absence of a supply of oxalacetic acid, acctaic" cannot enter the cycle. Intermediates for the cycle can arise from the carinxylation of pyruvic acid with CO, (e.g., to form malic acid), the addition of CO > to phosphcnnlpyruvic acid to yield oxalacetic acid, the formation of succinic acid from propionic acid plus CO, and the conversion of glutamic acid and aspartic acid to alpha-ketoglutaric acid and oxalacetic acid, respectively. See Fig. 3. [Pg.281]

Gibbons, H.S., Lin, S., Cotter, R.J., Raetz, C.R.H. Oxygen requirement for the biosynthesis of the S-2-hydroxymyristate moiety in Salmonella typhimurium lipid A. Function of LpxO, a new Fe /alpha-ketoglutarate-dependent dioxygenase homologue. J Biol Chem 275 (2000) 32940-32949. [Pg.22]

Pekovich SR, Martin PR and Singleton CK (1998) Thiamine deficiency decreases steady-state transketolase and pyruvate dehydrogenase but not alpha-ketoglutarate dehydrogenase mRNA levels in three human cell types. Journal of Nutrition 128, 683-7. [Pg.446]

Mizuno Y, Matuda S, Yoshino H, Mori H, Hattori N, Ikebe S (1994) An immunohistochemi-cal study on alpha-ketoglutarate dehydrogenase complex in Parkinson s disease. Ann Neurol 35(2) 204-210... [Pg.123]

Bhattacharya, R., Tulsawani, R.K. (2008). In vitro and in vivo evaluation of various carbonyl compounds against cyanide toxicity with particular reference to alpha-ketoglutaric acid. Drug Chem. Toxicol. 31 149-61. [Pg.266]

Satpute, R.M., Hariharakrishnan, J., Bhattacharya, R. (2008). Alpha-ketoglutarate and V-acetyl cysteine protect PCI 2 cells from cyanide-induced cytotoxicity and altered energy metabolism. Neurotoxicology 29 170-8. [Pg.268]

Tulsawani, R.K., Debnath, M., Pant, S.C., Om Kumar, Prakash, A.O., Vijayaraghavan, R., Bhattacharya, R. (2005). Effect of sub-acute oral cyanide administration in rats protective efficacy of alpha-ketoglutarate and sodium thiosulfate. Chemico-Biol. Int. 156 1-12. [Pg.269]

See other pages where Alpha-ketoglutarate is mentioned: [Pg.2134]    [Pg.1422]    [Pg.499]    [Pg.57]    [Pg.75]    [Pg.75]    [Pg.514]    [Pg.947]    [Pg.1422]    [Pg.386]    [Pg.103]    [Pg.57]    [Pg.75]    [Pg.75]    [Pg.549]    [Pg.249]    [Pg.24]    [Pg.42]    [Pg.42]    [Pg.125]    [Pg.126]    [Pg.271]    [Pg.105]    [Pg.622]    [Pg.1890]   
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2-ketoglutaric

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Alpha-ketoglutarate, cyanide antidote

Alpha-ketoglutaric acid

Sodium alpha ketoglutarate

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