Aerobic-Anaerobic Transitions

Fig. 14.1. Role ofthe pyruvate dehydrogenase complex (PDC) during aerobic/ anaerobic transitions in the development of Ascaris suum. PDC, pyruvate dehydrogenase complex AD, acyl CoA dehydrogenase ER, enoyl CoA reductase FR, fumarate reductase SDH, succinate dehydrogenase.

Huang, YJ., Walker, D., Chen, W., Klingbeil, M. and Komuniecki, R. (1998b) Expression of pyruvate dehydrogenase isoforms during the aerobic/anaerobic transition in the development of the parasitic nematode, Ascaris suum altered stoichiometry of phosphorylation/inactivation. Archives of Biochemistry and Biophysics 352, 263-270. 

Komuniecki, P.R. and Vanover, L. (1987) Biochemical changes during the aerobic-anaerobic transition in Ascaris suum larvae. Molecular and Biochemical Parasitology 22, 241-248. 

Komuniecki, R. and Komuniecki, P.R. (1995) Aerobic-anaerobic transitions in energy metabolism during the development of the parasitic nematode Ascaris suum. In Boothroyd, J.C. and Komuniecki, R. (eds) Molecular Approaches to Parasitolog. Wiley-Liss, New York, pp. 109-121. 

Ghiorse WC (1989) Manganese and iron as physiological electron donors and acceptors in aerobic-anaerobic transition zones. In Microbial mats. Cohen Y, Rosenberg E (eds) ASM Press, Washington DC, p 163-179... 

Storey, K. B. Hochachka, P. W. (1974b). Glycolytic enzymes in muscle of the Pacific dolphin role of pyruvate kinase in aerobic-anaerobic transition during diving. Comp. Biochem. Physiol. 49B, 119-128. 

THE AEROBIC/ANAEROBIC TRANSITION DURING HELMINTH DEVELOPMENT... 

Tanaka, N. (1998), Aerobic/anaerobic process transition and interactions in sewers, Ph.D. dissertation, Environmental Engineering Laboratory, Aalborg University, Denmark. 

Van Oordt, B.E., Tielens, A.G. and van den Bergh, S.G. (1989) Aerobic to anaerobic transition in the carbohydrate metabolism of Schistosoma mansoni cercariae during transformation in vitro. Parasitology 98, 409-415. 

Fig. 3. Protein synthesis in a maize primary root during ( ) one hr pulse labelling with [ HJleucine under aerobic conditions (b)-(e) pulse labelling with [ HJIeucine during the specified times under anaerobic conditions. The arrow labelled TPs indicates the position of the transition polypeptides. The unlabelled arrow indicates the position of alcohol dehydrogenase 1 (ADHl). From Sachs et al. (1980).

Most biochemically relevant high-spin systems have such short 7j-relaxation times that their EPR is broadened beyond detection at ambient temperatures. An exception is the class of S = 5/2 Mn" systems with D hx. Also, S = 7/2 Gd"1-based MRI shift reagents exhibit readily detectable room-temperature EPR spectra. Otherwise, aqueous-solution transition ion bioEPR is limited to complexes of S = 1/2 metals, in particular Cu", and to a lesser extent VIV02+, NiIn, Ni1, Mov, and Wv. Cupric is the stable oxidation state of biological copper under aerobic conditions, however, the other metals are stable as Vv, Ni", MoVI, and WVI, and, therefore, the other oxidation states associated with S = 1/2 paramagnetism may exhibit oxidative or reductive reactivity and may thus require specific experimental precautions such as strict anaerobicity over the course of the EPR experiment. 

Peripheral artery disease (PAD) patients usually feel leg pain when walking, which is caused by insufficient blood flow to keep up with energy demand. The P MRS data collected in a PAD patient group showed prolonged PCr recovery rate (or time constants) in the calf muscle after exhaustive exercise, suggesting the transition from anaerobic to aerobic energy metabolism is delayed due to impaired oxygen supply or mitochondria fimction caused by atherosclerosis. ... 

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