Administrative and responsible authority

FBTR (India) Department of Atomic Energy, India 

Fermi (USA) Power Reactor Development Co., Detroit Edison Co. 

PFBR (India) Bharatiya Nabhikiya Vidyut Nigam Limited (BHAVINI) 

SVBR-75/100 (Russian Federation) Agency for Atomic Energy 

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Aniline gave positive responses in the mouse bone-marrow micronucleus assay when administered via ingestion or intraperitoneal injection (Ashby et al. 1991 Westmoreland and Gatehouse 1991). However, the positive responses occurred only at a specific time after administration and at what the authors considered high doses (1,000 mg/kg orally and 300 mg/kg intraperitoneally). 

Clearly define cyber security roles, responsibilities, and authorities for managers, system administrators, and users. 

An official O M program is to be developed based on the inspection and assessment data, as soon as possible if ACM is located. Either the Asbestos Program Manager or a qualified consultant should develop the O M program. The written O M program should state clearly the O M pohcies and procedures for that building, identify and describe the administrative line of authority for that building, and should clearly define the responsibilities of key participants,... 

MAJOR limitation TO research on surface-exchange and flux measurements is the lack of sensitive, reliable, and fast-response chemical species sensors that can be used for eddy correlation flux measurement. Therefore we recommend that continued effort and resources be expended in developing chemical species sensors with the responsiveness and sensitivity required for direct eddy correlation flux measurements. This recommendation (I) was assigned the first priority in the report of the recent Global Tropospheric Chemistry workshop jointly convened by the National Science Foundation, the National Aeronautics and Space Administration, and the National Oceanic and Atmospheric Administration. The authors of the report recognized that the limited availability of fast, accurate chemical sensors is a major measurement challenge in the field of atmospheric chemistry. 

One hundred years ago, the relationship between an administrator and a worker was very hierarchical. The authority of the administrator generally went unquestioned, and workers simply did what they were told. In today s workplace, there is much more of a partnership between administrators and workers. While administrators are still responsible for achieving organizational goals and objectives, workers generally expect to have input as to how goals and objectives will be accomplished and also expect to share in the rewards when those goals are accomplished. 

The views in this paper do not necessarily reflect those of the Occupational Safety and Health Administration (OSHA). The authors are solely responsible for the contents of this paper. 

The principal regulatory authorities of the four countries are summarised in Table 4.3. To facilitate comparison, administrations have been divided according to their roles in the development and selection of risk-reduction measures, and their responsibilities with regard to implementing risk-reduction measures. Sweden and the UK present opposite extremes of centralisation. KemI is present in every activity listed in the table, whereas the roles and responsibilities of UK administrations are distributed across... 

The Executive Director is to be appointed by the Management Board following a open selection process. He is responsible for the day-to-day administration of the Authority and for its staff. His other main task will include preparation of the draft work programme and its subsequent implementation, for organisation of the selection process or the Scientific Committee and the Panels. 

Plan for adequate staff in advance. Make sure individuals understand their roles and responsibilities at all levels health authority, regional office, and clinic. Many individuals will require advance training, including administrative staff assigned to answer hotlines, process paper work from clinics, and carry out normal public health functions. Table 24.7 includes details related to personnel and logistics necessary for clinic operations. 

Imipenem, which is related to meropenem, has also been reported to cause toxic epidermal necrolysis (34). The authors stated that to the best of their knowledge, this was the first report of a possible cross-reaction between two classes of antibiotics in causing toxic epidermal necrolysis. The time between first administration and the occurrence of epidermal necrolysis is considerably shorter in recurrence or provocation testing (35,36). They also claimed that it is likely that the beta-lactam ring is responsible for this hypersensitivity reaction, citing the evidence that the patient had been given amoxicillin 15 days before the cephalosporin, and that could have served as the sensitizing event. They did not discuss whether aztreonam, a monobactam, also could have caused a cross-reaction however, it has been involved in two cases of fatal toxic epidermal necrolysis (37). 

The regulatory authorities involved in the registration of drug products are mainly the National Agency for Food and Drugs Administration and Control (NAFDAC) and the Pharmacists Council of Nigeria (PCN). The latter is responsible for registering an importer or local manufacturer. 

Furthermore, problems which evolve in developing countries in the establishment of drug control have been a consequence of the adaptation of the provisions established successfully elsewhere and of a complexity that precludes the effective implementation in the country of adoption. It should be emphasised that regulations and procedures must reflect conditions in the country and can then be adopted according to the available resources. However, regulatory authorities still have to implement the responsibilities that have been duly given by enactments. There is no doubt that the administrative and technical responsibilities which develop could be seen as steps toward quality assurance. 

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