Addendum

Since the original preparation of the manuscript for this book several interesting articles employing malic acid have appeared in the literature. 

1094 with approximately 8 1 selectivity. Use of sodium borohydride leads to a statistical 1 1 mixture. Acetylation and hydrogenolysis of the benzyl protecting group furnishes the 1 -acetoxyindolizidine 1095. 

Oxidation of the hydroxyl group of 1095 followed by treatment with hydroxylamine gives oxime 1096 as a 3 1 mixture of syn and anti isomers. Reduction of the oxime and subsequent acetylation provides A -acetylslaframine (1097). 

Asymmetric crotylboration and subsequent methylation furnishes 1105 with 20 1 dia-stereoselectivity. Introduction of the protected terminal hydroxyl group is accomplished by ozonolysis, reductive work-up, and j 7-methoxybenzylation. The epoxide is formed by intramolecular cyclization of the deprotected primary alcohol with the mesylated secondary alcohol. 

j5-unsaturated -lactone 1107 is constructed by Ghosez s methodology, which involves treating the epoxide with the lithio anion of methyl-3-phenylsulfonyl orthopropionate followed by acid hydrolysis and DBU-induced elimination. Reduction of the lactone to a lactol with diisobutylaluminum hydride and subsequent C-glycosidation furnishes aldehyde 1108 with a 4 1 epimeric ratio. This is then carried on to the desired fragment 1109. 

Chemistry Department, Birhheck College, University of London, Malet Street, London W. C. 1, England 

Addendum 1 (Section 2.3, p. Ill) Recently Chopra (C7a) demonstrated that 3,3, 5 -triiodothyronine or reverse Tj (rTa) is present in normal serum in a concentration of approximately 40 ng/100 ml and that there are large increases in rTa concentration in the serum of the newborn when serum Ta concentration is very low. As rTa has no physiological activity, he postulated that deiodination of T may switch from T, to rTa as regulatory mechanism controlling the biological action and metabolism of Ta. 

Addendum 2 (Section 3.7.2, p. 137, after 1st paragraph) The decreased concentration of serum Ta in tbe neonatal period is accompanied by a greatly increased concentration of 3,3, 5 -triiodothyronine or reverse Ta (C7a). 

Mukhtar, E. D., Smith, B. R., Pyle, G. A., Hall, R. and Vice, P., Relation of thyroid stimulating immunoglobulins to thyroid function and effects of surgery, radio-iodine and antithyroid drugs. Lancet 1, 713-715 (1975). 

University of Newcastle upon Tyne and Royal Victoria Infirmary, Newcastle upon Tyne, England 

Other Factors Affecting the Thyroid-Stimulating Hormone (TSH) 

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Addenda are issued at intervals between publication of complete editions. Information on tbe latest issues can be obtained from tbe American Society of Mechanical Engineers, 345 East 47tb Street, New York, N.Y. 10017. 

A new edition of the code is issued every 3 years. Between editions, alterations are handled by issuing semiannual addenda, which may be purchased by subscription. The ASME considers any issue of the code to be adequate and safe, but some government authorities specify certain issues of the code as their legal requirement. 

Construction Codes Rules for Construction of Pressure Vessels, Division 1, which is part of Section T11 of the ASME Boiler and Pressure Vessel Code (American Society of Mechanical Engineers), sei ves as a construction code by providing minimum standards. New editions of the code are usually issued every 3 years. Interim revisions are made semiannually in the form of addenda. Compliance with ASME Code requirements is mandatoiy in much of the United States and Canada. Originally these rules were not prepared for heat exchangers. However, the welded joint between tube sheet and shell of the fixed-tube-sheet heat exchanger is now included. A nonmandatoi y... 

Figure 11-23. Refrigerant safety group classification, per ANSI/ASHRAE Standard 34-1992, also see Table 11-3B. Used by permission ANSI/ASHRAE Standard 34-1992 including Addenda 34a-o and 34q-x, p. 5, 1992, 1996. American Society of Heating, Refrigerating, and Air Conditioning Engineers, Inc. All rights reserved.

Optimum depth of immersion depends on pitch-line speed. Deep immersion is permissible at low speeds because power losses from churning are low, but at moderate speeds the immersion depth should not be more than three times the tooth height. At the highest speeds, only the addenda of the teeth need be submerged (Figure 52.8). 

BIBLIOGRAPHY OF CRYSTAL STRUCTURES OF CARBOHYDRATES, NUCLEOSIDES, AND NUCLEOTIDES FOR 1979 AND 1980 ADDENDA AND ERRATA FOR 1970-1978 AND INDEX FOR 1935-1980... 

Supplement to "Catalogue des manuscrits alchimiques grecs". Vols. 2-3 Assisted by Annie Anderson and by Robina Addis. Vol. 3 includes appendixes, indexes and addenda and corrigenda. 

Blair, Rhonda L. "Select bibliography of Hermetic Studies, 1994-1995 with addenda, 1993." Cauda Pavonis, Spring 1996, 16-19. 

V. 1. Introduction, Texts, and Translation — V. 2. Notes on the Corpus Hermeticum — V. 3. Notes on the Latin Asclepius and the Hermetic Excerpts of Stobaeus — V. 4. Testimonia / with Introduction, Addenda and Indices by A.S. Ferguson. 

In the thermal bath modulation, a thermocouple is used as a weak link to the thermal bath, and the temperature of the bath is modulated sinusoidally in time. This configuration eliminates the need for a separate thermometer and heater on the sample, while retaining the ability to make measurements with minimal addenda. 

Various catalytic systems for H202- and 02-based oxidations catalyzed by POMs have been developed. Typical examples are listed in Table 13.1. The systems can be classified into four groups according to the stmctures of POMs (1) mixed-addenda POMs, (2) transition-metal-substituted POMs, (3) POMs, and (4) lacunary POMs. In this chapter, liquid-phase homogeneous oxidations by POMs with H202 and 02 are described according to the above classification. 

The next edition of this Code is scheduled for publication in 2011. There will be no addenda issued to this edition. 

This Appendix provides a listing of standards incorporated in this Code by reference, and the names and addresses of the sponsoring organizations. It is not practical to refer to a specific edition of each standard throughout the Code text instead, the reference dates for the specific editions are shown. For ASME codes and standards, specific edition reference dates are not provided rather, the latest published edition in effect at the time this Code is specified is the specific edition referenced by this Code. Subsequent issues and revisions of these referenced standards and any new standards incorporated in the Code by reference in Code Addenda will be listed (after review and acceptance by the Code Committee) in revisions of this Appendix. All identical specifications are indicated by the ASME/originating organization symbols. 

GENERAL NOTE The issue date shown immediately following the hyphen after the number of the standard (e.g., B16.9-1978, C207-1978, and A 47-77) is the effective date of the issue (edition) of the standard. Any additional number shown following the issue date and prefixed by the letter R is the latest date of reaffirmation [e.g., C101-1967 (R1977)]. Any edition number prefixed by the letter A is the date of the latest addenda accepted [e.g., B16.36-1975 (A1979)]. 

Provide concisely the information needed for the Committee s understanding of the inquiry, being sure to include reference to the applicable Code section, edition, addenda, paragraphs, figures, and tables. If sketches are provided, they shall be limited to the scope of the inquiry. The inquiry statement shall be technically correct and should be editorially correct. 

C3 and C4 of the glucon is an absolute one. Phenyl a-D-glucoside, phenyl /J-D-mannoside (II), methyl /S-D-guloside (III), involving reversal of the addenda at Cl, at C2, at C3 and C4, respectively, are not appreciably hydrolyzed by almond emulsin.29 Phenyl /3-D-glucoside (I) and phenyl... 

The Joint FAOAVHO Expert Committee on Food Additives (JECFA) includes Functional Use in the specifications published in Food and Nutrition Paper 52 and its Addenda. JECFA includes an indication of the functional use or uses, as part of its specifications of purity of additives. JECFA has developed these as part of the description of the additive, and although JECFA provides advice on specifications to the Codex Committee on Food Additives and Contaminants, the uses quoted in those specifications are not necessarily the same as the functions given for the same substance in the Codex INS system. Frequently more than one use is listed and these uses often refer to countries outside the EU, and may not include the reason for use listed by the EU. The various categories, uses or classes of additive used by the EU, INS and JECFA are listed in Table 11.2. With minor exceptions, the JECFA functional uses marked with an asterisk are generally regarded as processing aids and not additives and therefore outside the scope of this volume. 

JECFA Spec. The food additive specifications published in the FAO Food and Nutrition Paper 52, (FNP 52) and its Addenda (covering the years 1992 to 2000) are numbered Add from 1 to 8. The intention is to publish a consolidated volume, as a CD ROM and/or on the World Wide Web. 

Compendium of Food Additives Specifications. FAO Food and Nutrition Paper 52 and addenda 1 to 8. Published by the FAO, Vialle delle Terme di Caracalla, 00100 Rome. ISBN 92-5-104508-9. The compendium and addenda 1 to 7 are on the JECFA web site http //www.fao.org/ WAICENT/FAOINFO/ECONOMIC/ESN/Jecfa/Jecfa.htm... 

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