Dermatitis acneiform

Acneiform eruption after deep chemical peel is a common phenomenon appearing immediately after reepithelialization. Its etiology is multifactorial and is related to either exacerbation of previously existing acne or is due to over-greasing of newly formed skin. Short-term systemic antibiotics together with discontinuation of any oily preparations will usually provide satisfactory solution. 

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Post-peel acneiform dermatitis occurs readily under a greasy dressing (e.g. Vaseline ), and should be treated with oral antibiotics. It clears up in 6-8 days. 

It is common for acneiform dermatitis to develop under greasy dressings (see also the section above on microbial infections) after deep peels treated with the moist technique. Vaseline in fact creates an impermeable layer that acts as total occlusion. It is known that bacterial proliferation is much more rapid under occlusion than in the open air. Antibiotics and standard local treatments are used to treat post-peel acne. 

In the emergency room, treat as skin irritant. Prolonged exposure may cause acneiform dermatitis. 

The risk of hyper- or hypopigmentation is increased if deep penetration occurs on scrubbed or rubbed sites. A perioral acneiform dermatitis has been noted in a small number of patients, particularly on the chin (Figs 4.2 and 4.3). This phenomenon is unexplained. Nonetheless, it should be treated as a perioral dermatitis and further peels avoided cm the chin. Other rare occurrences are urticaria development but this responds to topical hydrocortisone (Fig. 4.4. ... 

Adverse reactions may include acneiform eruptions allergic dermatitis arthropathy multiple cases of cholestatic and fulminant hepatitis drowsiness fatigue headache hepatotoxicity resembling viral or alcoholic hepatitis impotence metallic or garlic-like aftertaste peripheral neuropathy polyneuritis optic or retrobulbar neuritis restlessness occasional skin eruptions. 

Pityrosporum folliculitis, a distinct clinical picture, is characterized by scattered itching acneiform, small follicular papules, sometimes pustules, on the back and shoulders of young patients. In contrast to acne, it is often aggravated by the use of local antibiotics and sun exposure. Hyphae are usually absent by light microscopic examination of pustular material. Pityrosporum yeasts take part in the pathogenesis of seborrheic dermatitis and have also been associated with certain facial eczemas in young atopic women. 

TOXICITY AND MONITORING Chronic use of potent topical glucocorticoids (e.g., diflo-rasone diacetate 0.05%, betamethasone dipropionate 0.05%) can cause skin atrophy, striae, telang-iectasias, purpura, and acneiform eruptions. Because perioral dermatitis and rosacea can develop after the use of fluorinated compounds on the face, they should not be used in this site. 

The medical literature has sparse reports. Excessive environmental heat in a Nigerian battery manufacturers induced sweating and maceration of the skin, especially over the anterior abdominal wall this predisposed five individuals wearing dark-coloured uniforms to clothing dermatitis. In the same report, one person working with bitumen developed an acneiform skin eruption (Olumide et al. 1983). 

Acneiform eruptions of the back are common in wetsuit wearers, but the major cause of irritant dermatitis is chafing by the closely fitting suit. Folliculitis is... 

Smith JD, Odom RB, Maibach HI (1975) Contact urticaria from cobalt chloride. Arch Dermatol 111 1610-1611 Soper LE, Vitez TS, Weinberg D (1973) Metabolism of haloge-nated anesthetic agents as a possible cause of acneiform eruptions. Anesth Analg 52 125-127 Stingeni L, Lapomarda V, Lisi P (1995) Occupational hand dermatitis in hospital environments. Contact Dermatitis 33 172-176... 

Six male healthy volunteers (mean age 31.5 years) received a single 45-mg oral dose containing 100 gCi [ C] dacomi-tinib. There were no serious adverse events, severe adverse events, or deaths during the study. In addition, there were no temporary discontinuations due to adverse events, and none of the subjects discontinued the study due to an adverse event. Mild adverse events were reported by two healthy volunteers dermatitis acneiform occurred in both subjects at approximately 100 h postdose, while dizziness, insomnia and photophobia occurred in one subject [60 ]. 

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