Inducing sweating

Pilocarpine (30) is one of a series of related alkaloids found in the South American plant genus Pilocarpus, known commonly as Jaborandi leaf, which was used in traditional medicine to induce sweating and urination. The molecular structure of (30) bears similarities to ACh (2) since the positively-charged N-atom and the lactone binding to the serine are about the same distance apart. Chewing the leaf results in typical features... 

In summer or in places with a warm dry climate, pungent, warm and bitter herbs should not be used at high doses because the pores of the body are not tightly closed and so the body fluid can easily be consumed by heat. This precaution relates to herbs that induce sweating, expel wind and cold, disperse the Lung-Qi, dry dampness and increase urination. 

The frequency of administration should be adjusted in some conditions these include herbal medicines which induce sweating or which have a purgative action. 

If the patient sweats easily, which suggests that pores are open at that time, formulas that induce sweating should not be used because they are so strong that they may cause overdispersion of Qi and body fluids. 

In the excess condition Stimulate the Yang and Qi, open the pores and induce sweating so as to expel wind-cold. 

First, herbs that are pungent and warm, enter the Bladder meridian and directly stimulate the Qi, induce sweating and expel wind and cold from the superficial region of the body are selected. 

Xiang Ru is the warmest of these three herbs. It is able to induce sweating, disperse wind and dampness, and release the exterior. It is especially useful... 

Gut Zhi serves as deputy it can promote blood circulation so as to enhance the action of the chief to induce sweating and relieve general pain of the body. 

Ma Huang is chosen to induce sweating and it focuses on the main pathological change. As it is a harsh and poisonous herb, it cannot be used in a large dosage. 

This formula can induce sweating and expel wind, cold and dampness. It is used in a common case of an excess condition of a wind-cold syndrome, or at the initial stage of a febrile disease. Patients suffer from chills, fever, headache with a heavy sensation, no sweating and have a blocked nose. A white tongue coating and a superficial, rapid pulse are seen in this syndrome. 

This formula is effective in inducing sweating and expelling wind-cold-dampness. It is a commonly used formula for treating an excess condition. Because there are many pungent and drying herbs in the formula, it should be used with caution or modified for treating patients with Yin deficiency. 

When the Qi and Yin are weak, they are not able to induce sweating, and the Qi pushes the... 

Qin Jiao is pungent, bitter and neutral, and enters the Stomach and Large Intestine meridians. As it is able to slightly induce sweating, it can disperse dampness in the superficial region of the body. It treats stiffness, heaviness and pain of the muscles. 

This formula is able to induce sweating and expel dampness in the superficial region. It treats damp-cold invasion of the superficial region and summer-heat that is constrained in the body. The manifestations are chills, fever, no sweat, general pain and heaviness, fullness in the stomach, irritation, thirst, scanty urine, a white, sticky tongue coating and a soft and rapid pulse. 

The combination of herbs in the formula demonstrates the strategy of inducing sweating together with clearing heat. 

Ma Huang Ephedrae herba) Stimulates the Yang and Qi of the Lung and Bladder meridians, induces sweating and releases the exterior ... 

Benefits Elderflowers have traditionally been used for colds and fevers as their main action is claimed to be to induce sweating and reduce temperature. Folklore Many old superstitions surround the elder. It was considered most unwise to cut down an elder tree without fust seeking permission of the elder mother spirit in the tree (Bown, 2003 British Herbal Medicine Association, 1983 Gruenwald et al., 2002 Hutchens, 1973 Shealy, 1998 Tierra, 1998). 

The low plasma PCO2 leads to decreased renal tubular reabsorption of bicarbonate and increased renal excretion ofNa , K, and water. Water also is lost by salicylate-induced sweating (especially in the presence of hyperthermia) and hyperventilation dehydration, which can be profound, particularly in children, rapidly occurs. Because more water than electrolyte is lost through the lungs and by sweating, the dehydration is associated with hypernatremia. Prolonged exposure to high doses of salicylate also causes depletion ofK due to both renal and extrarenal factors. 

Pilocarpine is used principally as a diaphoretic, that is, to induce sweating, especially in nephritis, to relieve the kidneys and to remove toxic metabolites. The secretion of 3 liters of sweat can easily be achieved, and as much as 8 g. of nitrogen can be eliminated. The alkaloid is also employed as a milder substitute for physostigmine in the treatment of ocular diseases. Pilocarpine is reputed to stimulate the growth of hair, and jaborandi extracts are therefore employed to some extent as constituents of hair lotions. 

About 5 mg of antimony shows a strong diaphoretic action (induces sweating), while 50 mg or more acts as an emetic. There are rumours that Mozart s death was due to acute antimony tartarate poisoning. It is also known that several Victorian doctors used antimony to dispose quietly of their unwanted wives or relatives. Antimony trioxide is used as a flame retardant in plastics, while Antimony chloride is used as a catalyst and a colouring agent. 

Documented effects Used as an antipyretic, as a diuretic for treatment of urogenital diseases, and as a diaphoretic and antiinflammatory (Kurochkin 1998). A bath infused with the herb is used to treat diathesis in children. An infusion of the herb is drank to induce sweating and to treat common colds (Grinkevitch 1991). Although the content of flavonoids in the flower heads was found to be half of that found in the herb, an extract from flowers had nearly 2 times higher antioxidant activity (Wolniak et al. 2007). 

Pilocarpine an imidazole alkaloid, and the chief alkaloid from the leaves of Brazilian Pilocarpus species. M, 208.26, m.p. 34 °C, b.p.j 260 C, [a]g -100.5° (CHCI3). P. is used therapeutically as a diaphoretic, i.e. to induce sweating, and especially in nephritis to relieve the kidneys and remove toxic metabolites. It is also used in opthalmology as an antagonist of atropine, and for regulating the intraocular pressure in glaucoma. 

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