Acinetobacter infections

Gram-negative bacilli Acinetobacter Infections in various tissues hospital-acquired infections An aminoglycoside + ticarcillin Imipenem or meropenem ciprofloxacin trimethoprim-sulfamethoxazole ampi-cillin/sulbactam... 

Multidrug-resistant Pseudomonas and Acinetobacter infections are of concern to clinicians because of the limited therapeutic options available for the treatment of such infections. This concern has led... 

In a retrospectively assessment of renal function before and after treatment with intravenous cohstin for Acinetobacter infection in 54 mainly critically ill patients, there was a clinically significant increase in serum creatinine concentration in six patients, all of whom had normal renal function at baseline, but other causes of nephrotoxicity could not be ruled out there were no differences in patients with pre-existing renal impairment [180 ]. 

Weber, D. J., Rutala, W. A., Miller, M. B., Huslage, K., and Sickbert-Bennett, E. (2010). Role of hospital surfaces in the transmission of emerging health care-associated pathogens Norovirus, Clostridium difficile, and Acinetobacter species. Am. ]. Infect. Control 38, S25-S33. 

Freeman, R. Sisson, P. R. Noble, W. C. Lightfoot, N. F. An apparent outbreak of infection with Acinetobacter calcoaceticus reconsidered after investigation by pyrolysis mass spectrometry. Zbl. Bakt. 1997, 285, 234-244. 

Skin and skin structure infections - E. faecalis, S. aureus (penicillinase-producing), S. epidermidis, E. coli, Klebsiella sp., Enterobacter sp., P. vulgaris, P. rettgeri, M. morganii, P. aeruginosa, Serratia sp., Citrobactersp., Acinetobacter sp., Bacteroides sp., Fusobacterium sp. Peptococcus sp., Peptostreptococcus sp. 

Skin and skin structure infections- Skin and skin structure infections, including abscesses, cellulitis, infected skin ulcers, and wound infections caused by S. aureus (including penicillinase-producing strains) Streptococcus pyogenes, group D streptococcus including . faecalis, Acinetobacter sp. including iA. calcoaceticus] Citrobactersp.] E. coli] Enterobacter cloacae, K. pneumoniae]... 

Jacobsen SB (2001) Gas hydrates and deglaciations. Nature 412 691-693 Jakosky BM, Shock EL (1998) The biological potential of Mars, the early Earth, and Europa. J Geophys Res 103 19,359-19,364 Jawad A, Snelling AM, Heritage J, Hawkey PM (1998) Exceptional desiccation tolerance of Acinetobacter radioresistens. J Hosp Infect 39 235-240 Jenkins GS (2000) The snowball Earth and Precambrian climate. Science 288 975-976... 

Enterobacter species Acinetobacter species Salmonella species Proteus species Klebsiella species Serratia marcescens respiratory tract infections endophthalmitis... 

Ruiz J, Nunez ML, Perez J, Simarro E, Martinez-Campos L, Gomez J. Evolution of resistance among clinical isolates of Acinetobacter over a 6-year period. Eur J Clin Microbiol Infect Dis 1999 18(4) 292-5. 

Jimenez-Mejias ME, Pichardo-Guerrero C, Marquez-Rivas FJ, Martin-Lozano D, Prados T, Pachon J. Cerebrospinal fluid penetration and pharmacokinetic/phar-macodynamic parameters of intravenously administered colistin in a case of multidrug-resistant Acinetobacter bau-mannii meningitis. Eur J CUn Microbiol Infect Dis 2002 21(3) 212-14. 

Levin AS, Barone AA, Penco J, et al. Intravenous coUstin therapy for nosocomial infecUons caused by multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumarmii. CUn Infect Dis 1999 28 1008-1011. 

Let us review. Escape from restriction is the commonest causes of epidemics by really new epidemics encountered so far in prehistorical and historical time. It might typically involve a mutation which, for example, overrides the immune system of a new host or permits entry into the cell of the new host. There are some 60 well-known zoonotic examples, if not exactly running from A to Z, certainly from Acinetobacter pneumonia to Yersiniosis that infect humans. The Z disease if it comes, may be aptly named the analogous Greek letter omega has been used in many science fiction stories for the ultimate bacterial or viral disease The Omega Man was a film in which Charlton Heston played the last uninfected man on Earth. Recent real-life examples include the recent outbreak in Toronto of bird flu (from Asian water birds), SARS (from the civet, etc.), anthrax (sheep), ebola (from rodents), and acquired CJD (sheep, mad cow). 

Nervous system Of 7 patients from a Thai hospital and 17 patients who received intrathecal cohstin for drug-resistant Acinetobacter baumannii central nervous system infection identified in a literature review, three developed chemical ventriculitis and one had treatment-emergent seizures [101 ]. The dosage regimens of intrathecal colistin varied. There was an overall clinical cure rate of 83% and a microbiological cure rate of 92%. 

---