Water-soluble vitamins flavins

Vitamin B complex is the collective term for a number of water-soluble vitamins found particularly in dairy products, cereals and liver.Vitamin B (thiamine) is used by mouth for dietary supplement purposes and by injection in emergency treatment of Wernicke-Korsakoff syndrome. Vitamin B2 (riboflavin) is a constituent of the coenzyme FAD (flavine adenine dinucleotide) and FMN (flavine mononucleotide) and is therefore important in cellular respiration. Vitamin Be (pyridoxine) is a coenzyme for decarboxylases and transamination, and is concerned with many metabolic processes. Overdose causes peripheral neuropathy. It may be used medically for vomiting and radiation sickness and for premenstrual tension. Pyridoxine has a negative interaction with the therapeutic use of levodopa in parkinsonism by enhancing levodopa decarboxylation to dopamine in the periphery, which does not then reach the brain. The antitubercular drug isoniazid interferes with pyridoxine, and causes a deficiency leading to peripheral neuritis that may need to be corrected with dietary supplements. Vitamin B ... 

Electrochemical detection in LC provides a sensitive assay method for certain vitamins, such as AA, folates, and flavins. AA may be easily detected with femtomolar sensitivity. Sample preparation and matrix interference problems limit the routine applicability of electrochemistry in the analysis of water-soluble vitamins currently to AA. 

Other popular sensitisers of singlet oxygen formation are acridin orange, methylene blue, and tolui-din blue (formula [79]) but many biological compounds are also effective in vitro, such as the water-soluble vitamin riboflavin and its derivatives flavin mononucleotide and flavin adenine dinucleotide. 

TLC can be used to differentiate riboflavin from FMN (flavin mononucleotide) and some flavin analogs using various mobile phases riboflavin phosphates can be separated from riboflavin biphosphates, whereas the isomeric riboflavin phosphates co-migrate in all chromatographic systems studied (Nielsen et al., 1986). Bhushan and AH (1987) used TLC to analyze riboflavin in different matrices and also to separate and identify vitamin B2 from other water-soluble vitamins (Bi, Bj, and B12). Thielemann (1974) used TLC to separate and identify vitamin B2 from fat-soluble vitamins (A, Di, and E) in multivitamin preparations. 

Description. Riboflavin is a water-soluble B-complex vitamin, also known as vitamin B2. In the body, riboflavin functions in the mitochondrial electron transport systan as the coenzymes, flavin adenine dinucleotide and flavin mononucleotide. ... 

A member of the water-soluble B complex of vitamins. It is a constituent of the flavin coenzymes, flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which participate in biological reduction-oxidation reactions. Riboflavin is usually obtained in the diet from plant sources. Deficiency of the vitamin (ariboflavinosis) can result in a rough scaly skin and oral, anal and vaginal lesions. 

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