Vitamin bone, healing

Rickets, which is diagnosed by X-rays of leg bones, heals promptly with 4000 lU of oral vitamin D per day, with treatment for a month. In performing this treatment, the physician needs to monitor plasma 25 hydroxyvitamm D to make certain that they are raised to the normai range. The bone abnormalities (visible by X-ray) disappear gradually over the course of 3-9 months. Parents are instructed to take their infants outdoors for about 20 minutes per day with their faces exposed in order to prevent deficiency. Osteomalacia is treated by eating 2500 ID/day for about three months. Measurements of 25-hydroxyvitamin D, calcium, and parathyroid hormone are also part of the treatment process. 

Hyperparathyroidism and aluminium hydroxide lead to aluminium-related bone disease however, total parathyroidectomy does not lead to failure of aluminium mobilization after renal transplantation. This man had satisfactory graft function, and the aluminium excretion that was achieved by deferoxamine suggests that the renal transplant was not the limiting factor for the mobihzation of aluminium. The most likely explanation was that he developed adynamic bone through a combination of vitamin D deficiency, hypoparathyroidism, and aluminium deposition. Vitamin D supplementation failed to prevent the osteodystrophy on its own. When aluminium chelation therapy was used, bone healing occurred and his symptoms improved. 

Spontaneous reports of osteoporosis, osteopenia, bone fractures, and delayed healing of bone fractures have been seen in the isotretinoin population. While causality to isotretinoin has not been established, an effect cannot be ruled out. Physicians should use caution when prescribing isotretinoin to patients with a genetic predisposition for age-related osteoporosis, a history of childhood osteoporosis conditions, osteomalacia, or other disorders of bone metabolism. This would include patients diagnosed with anorexia nervosa and those who are on chronic drug therapy that causes drug-induced osteoporosis/osteomalacia and/or affects vitamin D metabolism, such as systemic corticosteroids and any anticonvulsants. 

Deficiency symptoms In vitamin C deficiency scurvy develops. It is characterized by ecchymosis, petechiae, swollen and bleeding gums, subperiosteal haemorrhage, bones are painful to touch, impaired wound healing, anaemia, loosening of teeth and gingivitis. 

A partial list of physiological functions til at have been determined to be affected by vitamin C deficiencies includes (1) absorption of iron (2) cold tolerance, maintenance of adrenal cortex (3) antioxidant (4) metabolism of tryptophan, phenylalanine, and tyrosine (5) body growth (6) wound healing (7) synthesis of polysaccharides and collagen (8) formation of cartilage, dentine, bone, and teeth and (9) maintenance of capillaries. 

Vitamin C is essential for the healing of wounds, and for the repair and maintenance of cartilage, bones, and teeth. 

The richest sources of vitamin C are citrus fruits (e.g., lemon, oranges), tomatoes, potatoes, green chilies, and human milk. Severe deficiency causes scurvy and is prevalent in malnourished infants, children, adults, alcoholics, and drug addicts. Symptoms such as bleeding gums, deformed teeth, brittle bones, impaired wound healing, anemia, and growth retardation are observed. 

It has been suggested that supplements may be beneficial in the healing of bone fractures. There is some evidence that patients with osteoporosis (Section 3.4.3) have low circulating concentrations of vitamin K, and some evidence that supplements ofvitaminKmay retard the progression of osteoporosis (Vermeer etal., 1995, 1996 Feskanichet al., 1999). 

Which vitamin is essential to sound bones and wound healing ... 

Healing of broken bones, rickets, and osteomalacia is speeded up when there is sufficient phosphorus working with calcium and vitamin D. 

Vitamin C is important in the growth and repair of connective tissue, teeth, bones, and cartilage. In addition, it promotes wound healing, enhances absorption of iron, and functions in the biosynthesis of several hormones. Vitamin C also serves as an antioxidant in many biological processes. It is almost a part of folk medicine... 

But vitamin A has been shown to have a number of other functions in the body. It is essential for the maintenance of growth, bone formation, reproduction, proper immune system function, and healing of wounds. A number of additional claims have been made for the compound, although evidence is not as strong as it is for the above functions. For example,... 

Vitamin C Vitamin G, ascorbic add, helps destroy invading bacteria aids the synthesis and activity of interferon, which prevents the entry of viruses into cells and combats the ill effects of toxic substances, including drugs and pollutants. It also aids in the synthesis of collagen, which is present in cartilage, bone, tendons, and connective tissue, and is therefore important in the healing of wounds and for infants and pregnant women. In addition, vitamin G is an antioxidant. 

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