Tumors metastatic carcinoid

B. Indications and use Sandostatin is indicated to reduce blood levels of growth hormone and IGF-I (somatomedin-C) in acromegaly patients who have had inadequate response to or cannot be treated with surgical resection, pituitary irradiation, or bromocriptine mesylate at maximally tolerated doses. It is also indicated for the symptomatic treatment of patients with metastatic carcinoid tumors, where it suppresses or inhibits the severe diarrhea and flushing episodes associated with the disease, and for the treatment of the profuse watery diarrhea associated with VIP (vasoactive intestinal peptide)-secreting tumors (vipomas). [Pg.241]

Treatment of carcinoid and vasoactive intestinal peptide acromegaly (reduce blood levels of growth hormone), symptomatic treatment of metastatic carcinoid tumors, and profuse water diarrhea associated with intestinal tumors... [Pg.485]

Control of symptoms in patients with metastatic carcinoid (severe diarrhea and flushing episodes) and vasoactive intestinal peptide-secreting tumors (profuse water y diarrhea)... [Pg.137]

A 70-year-old patient with a metastatic carcinoid tumor of the liver presented with a hypertensive crisis after being given pethidine 10 mg/hour by continuous intravenous infusion (4). The patient remained hypertensive with a systolic blood pressure of 210 mmHg, even after chemoembolization of the tumor. The blood pressure... [Pg.2791]

FIGURE 10.36 A, Metastatic carcinoid involving the liver. Immunoperoxidase stain for chromogranin A shows strong positivity in tumor cells. B, Metastatic carcinoid involving the liver. Immunoperoxidase stain for serotonin shows strong positivity in tumor cells. [Pg.320]

Carcinoid tumor, metastatic, lung 80 primary Sclerosing hemangioma of 100 lung—cuboidal cells and polygonal cells... [Pg.376]

Tash JA, Reuter V, Russo P. Metastatic carcinoid tumor of the prostate. J Urol. 2002 167 2526. [Pg.652]

Carcinoid tumors—Symptomatic treatment of patients with metastatic carcinoid tumors, where... [Pg.509]

Approved uses for the drug include the control of diarrhea associated with vasoactive intestinal peptide tumors and metastatic carcinoid tumors. Other uses include the control of diarrhea associated with AIDS and with pituitary tumors. [Pg.227]

Items 1-2 Your patient has been diagnosed with a rare metastatic carcinoid tumor. This neoplasm is releasing serotonin, bradykinin, and several unknown peptides. [Pg.164]

Zuetenhorst JM, Taal BG (2005) Metastatic carcinoid tumors a clinical review. Oncologist 10 123-131... [Pg.92]

Gupta S, Yao JC, Ahrar K et al (2003) Hepatic artery embolization and chemoembolization for treatment of patients with metastatic carcinoid tumors the M.D. Anderson experience. Cancer J 9 261-267... [Pg.137]

Shapiro RS, Shafir M, Sung M, Warner R, Glajchen N (1998) Cryotherapy of metastatic carcinoid tumors. Abdom Imaging 23 314-317... [Pg.164]

Moertel CG, Hanley JA (1979) Combination chemotherapy trials in metastatic carcinoid tumor and the malignant carcinoid syndrome. Cancer Clin Trials 2 327-334... [Pg.187]

Drougas JG, Antony LB, Blair TK, et al. (1998) Hepatic artery chemoembolization for management of patients with advanced metastatic carcinoid tumors. Am J Surg 175 408-412... [Pg.188]

Schell SR, Camp RE, Caridi JG, et al. (2002) Hepatic Artery Embolization for Control of Symptoms, Octreotide Requirements, and Tumor Progression in Metastatic Carcinoid Tumors. J Gastrointest Surg 6 664-670... [Pg.188]

Hajarizadeh H, Ivancev K, Mueller CR, et al. (1992) Effective palliative treatment of metastatic carcinoid tumors with intra-arterial chemotherapy/chemoembolization combined with octreotide acetate. Am J Surg 163 479-483... [Pg.188]

Octreotide, a synthetic octapeptide analog of endogenous somatostatin, is prescribed for the symptomatic treatment of carcinoid tumors and vasoactive intestinal peptide-secreting tumors (VIPomas). Metastatic intestinal carcinoid tumors secrete excessive... [Pg.682]

Brain tumors Carcinoid tumors Chronic lymphocytic leukemia Colorectal cancer Esophageal cancer Head and neck cancers Kaposi s sarcoma Metastatic melanoma Mycosis fungoides Non-small-cell lung cancer Ovarian cancer ... [Pg.2290]

Stain Carcinoid Tumor Paraganglioma Medullary Melanoma Renal Cell Metastatic (Thyroid CA, Carcinoma, or Lung Carcinoma)... [Pg.272]

These three neuroendocrine tumors of the larynx all display positivity for typical neuroendocrine markers such as chromogranin, synaptophysin, and neuron-specific enolase. They may also be positive for carcinoembryonic antigen (CEA) or epithelial membrane antigen (EMA). Atypical carcinoid and SCNEC can also express other neuroendocrine markers such as serotonin, calcitonin, and somatostatin. TTE-1 is probably not a useful marker to distinguish metastatic pulmonary small cell carcinoma from primary tumors in the head and neck because up to 50% of extrapulmonary small cell carcinomas are positive for TTR-l.i 8... [Pg.273]

Mooney EE, Dodd LG, Otrry TD, et al. Middle ear carcinoid an indolent tumor with metastatic potential. Head Neck. 1999 21(l) 72-77. [Pg.290]

This is one differential in which immunohistochemistry can be of utmost importance. Numerous cytologic and architectural similarities exist between HCC and metastatic well-differentiated neuroendocrine neoplasia (carcinoids and pancreatic endocrine neoplasia) They are both cellular, stroma-poor tumors that have a delicate sinusoidal vasculature and relatively monotonous cells with fair amount of cytoplasm and round nuclei. A panel of "neuroendocrine markers" (chromogranin, synapto-physin, and CD56) combined with "hepatocytic" markers (Hep Par-1 and polyclonal-CEA, and FISH for albumin) can be helpful. [Pg.573]

FIGURE 18.46 Carcinoid tumors in the ovary can be found with other tissues as a component of a teratoma. They can aiso be primary in the ovary but not associated with other teratomatous tissues, in which case they are viewed as monodermai teratomas. Finaiiy, they can be metastatic from the appendix, smaii intestine, or other sites. Regardiess of their origin, they show cytopiasmic staining for chro-mogranin, as shown here, and for synaptophysin. [Pg.739]

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