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Vasoactive intestinal peptide

Vasoactive Intestinal Peptide and Pituitary Adenylate Cyclase Activating Peptide. Vasoactive intestinal peptide (VIP)... [Pg.578]

USP (Sandostatiu) flutamide (Rulexin) [13311-84-7] C11H11F3N2O3 276.21 (66) tumors vasoactive intestinal peptide-secretory tumors metastatic prostatic stools vomit-ing abdomiaal pain pain on iujection diarrhea... [Pg.443]

Pituitary Adenylyl Cyclase-activating Polypeptide (PACAP) is a 38-amino acid peptide (PACAP-38), which is widely expressed in the central nervous system. PACAP is most abundant in the hypothalamus. It is also found in the gastrointestinal tract, the adrenal gland and in testis. Its central nervous system functions are ill-defined. In the periphery, PACAP has been shown to stimulate catecholamine secretion from the adrenal medulla and to regulate secretion from the pancreas. Three G-protein coupled receptors have been shown to respond to PACAP, PAQ (PACAP type I) specifically binds PACAP, VPACi and VPAC2 also bind vasoactive intestinal peptide (VDP). Activation of PACAP receptors results in a Gs-mediated activation of adenylyl cyclase. [Pg.979]

ATP with acetylcholine and vasoactive intestinal peptide in some parasympathetic nerves... [Pg.1048]

Vasoactive Intestinal Peptide(VIP) is a 28-amino acid peptide, which has a variety of actions as a neuroendocrine hormone and a putative neurotransmitter. It... [Pg.1272]

Brenneman DE, Westbrook GL, Fitzgerald SP, Ennist DL, Elkins KL, Ruff MR, Pert CB (1988) Neuronal cell killing by the envelope protein of HIV and its prevention by vasoactive intestinal peptide. Nature 335(6191) 639-642... [Pg.22]

This was the original hypothesis put forward by Lee (1970) and expanded by Ogilvie et al. (1973). Secretory products of N. brasiliensis do indeed decrease the amplitude of contractions of segments of uninfected rat intestine maintained in an organ bath, but a role for AChE in this phenomenon was discounted due to the heat stability of the parasite factor, and the inability to duplicate the effect with AChE from the electric eel (Foster et al., 1994). Subsequent investigations demonstrated that the suppression of contraction could be duplicated by a 30-50 kDa fraction of secreted products, which contained a protein of 30 kDa that was immunologically cross-reactive with mammalian vasoactive intestinal peptide (VIP). Moreover, an antibody to porcine VIP significantly reduced the inhibitory effect of parasite-secreted products on contraction in vitro (Foster and Lee, 1996). [Pg.225]

Laburthe, M., Breant, B., and Rouyer-Fessard, C. (1984) Molecular identification of receptors for vasoactive intestinal peptide in rat intestinal epithelium by covalent cross-linking. Eur. J. Biochem. 139, 181-187. [Pg.1085]

ANF atrial natriuretic peptide CGRP calcitonin gene-related peptide VIP vasoactive intestinal peptide... [Pg.318]

Hormones and neuronal activity affect brain glycogen metabolism. Glycogen is affected by hormones endogenous to the brain including vasoactive intestinal peptide and noradrenaline, as well as circulating hormones, such as insulin [61, 63, 64]. The mechanism whereby insulin exerts an effect on glycogen metabolism in brain has not been determined [63]. Glycogen metabolism in brain, unlike in other tissues, is controlled locally, due to differential local metabolic rates. [Pg.538]

Secretory diarrhea occurs when a stimulating substance (e.g., vasoactive intestinal peptide [VIP], laxatives, or bacterial toxin) increases secretion or decreases absorption of large amounts of water and electrolytes. [Pg.269]

Carrero I, Femandez-Moreno MD, Perez-Albarsanz MA, et al. 1989. Lindane effect upon the vasoactive intestinal peptide receptor-effector system in rat enterocytes. Biochem Biophys Res Comm 159(3) 1391-1396. [Pg.169]

Calcitonin gene-related peptide Vasoactive intestinal peptide Galanin Somatostatin... [Pg.298]

Specific hormones Insulin, glucagon, somatostatin, gastrin, pancreatic polypeptide, serotonin, vasoactive intestinal peptide, cholecystokinin... [Pg.428]


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