Troubleshooting guide

Many different guides are provided by equipment and material suppliers. However, 

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Set up practical I uselii TROUBLESHOOTING GUIDE based on causes remedies of potential faults. ... 

With all types of plastic processes, troubleshooting guides are set up to take fast, corrective action when products do not meet their performance requirements. This problem-solving approach fits into the overall fabricating-design interface. One brief example of troubleshooting an RP/composite is in Table 8-44. 

Capron Nylon Troubleshooting Guide for Injection Molding... 

Problems with the mechanics of a procedure can involve an improperly diluted sample (perhaps manifested by an absorbance reading that is greater than specified or expected), an obstruction in the sample or reference beam, an improperly aligned source or mirror, the incomplete programming of a scan, or improper or inappropriate software entry. In these cases, the operator will need to carefully examine his or her technique or procedure, or instrumental parameters, such as the optical path, perhaps with the help of the instrument troubleshooting guide, to solve the problem. 

Problems that arise with HPLC experiments are usually associated with abnormally high or low pressures, system leaks, worn injectors parts, air bubbles, or blocked in-line filters. Sometimes these manifest themselves on the chromatogram and sometimes they do not. In the following subsections, we address some of the most common problems encountered, pinpoint possible causes, and suggest methods of solving the problems. You can also refer to the troubleshooting guide in Chapter 12 for possible solutions. 

Spruce, B. and Bakalyar, S. R., Troubleshooting Guides for HPLC Injector Problems, Rheodyne.com/Docs/Tech/Docs/TSl.html... 

Operator e.g., operator trained with CE, do s and don ts, training with the test method, troubleshooting guide for test method available... 

Often troubleshooting guides are provided by equipment manufacturers for common problems. These guides are helpful for many of the simpler problems associated with the equipment. Some resin manufacturers are an excellent resource for troubleshooting processing problems that are specific to a resin. Subject matter experts or extrusion consultants are also resources for troubleshooting an extrusion process. 

Discussed herein are the general requirements of the immunohistochemistry laboratory for compliance with CLIA-88. In addition, a troubleshooting guide for immunoperoxidase procedures is included. 

Technical documentation (input-output list, alarms and safety list, automatic and manual control listings, regulation loop descriptions, calibration guide, maintenance guide, troubleshooting guide, etc.)... 

Table B1.1.1 Troubleshooting Guide for the Modified Lowry Protein Assay... 

Table B1.1.3 Troubleshooting Guide for Biuret Protein Assay...

Table B1.1.4 Troubleshooting Guide for Coomassie Plus Protein... 

The main disadvantage of all Bradford-type protein assay reagents is that they are not compatible with surfactants at concentrations routinely used to solubilize membrane proteins. With some exceptions, the presence of a surfactant in the sample, even at low concentrations, causes precipitation of the reagent. Table B1.1.4 is a brief troubleshooting guide for this technique. 

Table D2.2.1 Troubleshooting Guide for Headspace Chromatography of Lipid Oxidation Products... 

Table F1.3.4 Troubleshooting Guide for HPLC Analysis of Anthocyanins and Anthocyanidins...

It is imperative that the HPLC instrument, including the detector, is working correctly. The easiest way to check this is by first running a blank. If there is no response, one can move onto injecting the standards. If there is a response to the blank, the column may have been overloaded prior to this run. Refer to a troubleshooting guide for the specific HPLC system. The internet is also an invaluable source for troubleshooting (e.g., see Internet Resources). Keep in mind that the source of the problem may not be the system but may in fact be the column. 

Table 11.5.1 Troubleshooting Guide for MALDI-MS Analysis of Flavonol Glycosides...

COOLING WATER PROGRAM CONTROL PARAMETERS AND TROUBLESHOOTING GUIDE... 

HPLC Troubleshooting Guide, Guide 826. Supelco Division of Rohm and Haas, Bellefonte, Pennsylvania, 1991. 

Very often the manuals are the weakest point of many excellent packages. The manual will be your first and most often your only assistant and helper. A good manual should not only describe all possibilities on how to operate the system, but should also provide clear instructions on how to start using the system - possibly with actual examples, and should include a comprehensive troubleshooting guide. In other words the manual should be useful from the very beginning until the system has been mastered, and beyond. 

Set UP practical ef . TROUBLESHOOTING GUIDE DasecK causes emedas o polenta1 tau ts... 

Technical Report, A Troubleshooting Guide to Plumbing Problems in HPLC, MAC-MOD Analytical Inc., Chadds Ford, PA. 

Records also help prevent mistakes, such as introducing water into a silica column, or precipitating buffer in the system by adding too much organic solvent. Many analysts occasionally modify their HPLC systems for a variety of reasons. Reliable records are the best way to ensure that a modification does not introduce problems. For problems relating to pumps, detectors, automatic samplers, and data systems, instrument manuals provide suitable troubleshooting guides. 

If the chlorination system does not perform as expected, the shortcomings and troubleshooting guide should be studied. 

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