Tri butyl amine

Deoxy-a-D-ribosyl-l-phosphate 20, a key substrate in the preparation of 2 -deoxynucleosides, was stereoselectively prepared by crystallization-induced asymmetric transformation in the presence of an excess of ortho-phosphoric acid and tri( -butyl)amine under strictly anhydrous conditions (Scheme 2).7 Initial Sn2 displacement of Cl in ot-glycosyl chloride 16 by phosphoric acid resulted in a 1 1 a/p anomeric mixture of 17 and 18 due to the rapid anomerisation of the a-chloride in polar solvents. Under acidic conditions, in the presence of an excess of H3P04, an equilibration between the a and p anomers gradually changed in favour of the thermodynamically more stable a-counterpart. By selective crystallization of the mono tri( -butyl)ammonium salt of the a-phosphate from the mixture, the equilibrium could be shifted towards the desired a-D-ribosyl phosphate 18 (oc/p = 98.5 1.5), which was isolated as bis-cyclohexylammonium salt 19 and deprotected to furnish compound 20. 

Cl1 HI60 p-tert-amyl phenol 80-46-6 1.783E-K10 131.670 25346 C12H27N tri butyl amine 102-82-9 1.874E-H10 137.410... 

In early 1970 s Norman and coworkers [4] reported the first coupling reactions of aryl halides using palladium(ll) acetate under reaction conditions typical for the Heck reaction. They found that aryl iodides readily couple when they are treated with the catalytic quantity of palladium(Il) acetate in refluxing triethylamine or tri- -butyl amine to produce biaryls in moderate to good yields, Table 7. 

Experimental data is presented to support the observation that generation of dibromocarbene in dichloromethane solution using tri- -butyl amine as catalyst is efficient and efficacious. A dozen olefins are dibromocyclopropanated in yields ranging from 60%-89% [see Eq. 4.1 and Sect. 2.2]. 

ECF is successfully used on a commercial scale to produce certain perfluoroacyl fluorides, perfluoroalkylsulfonyl fluorides, perfluoroalkyl ethers, and perfluoroalkylamines. The perfluoroacyl fluorides and perfluoroalkylsulfonyl fluorides can be hydrolyzed to form the corresponding acid and acid derivatives. Examples include perfluorooctanoyl fluoride [335-66-0] perfluorooctanoic acid [335-67-1] perfluorooctanesulfonyl fluoride [307-35-7] perfluorooctanesulfonic acid [763-23-1] and tris(perfluoro- -butyl)amine [311-89-7]. 

Free-radical additions of trichlorosilane to acetylenes initiated by benzoyl peroxide were stereospecific trans additions, giving only cis adducts. The same workers observed that tri-n -butyl amine also catalyzed addition of trichlorosilane to phenylacetylene but gave a mixture of cis- and trans -l-phenyl-2-trichlorosilylethene, 1,1-phenyltrichlorosilylethene, and 1-phenyl-l,2-bistrichlorosilylethane (54). No stereospecificity was observable with the amine as catalyst. 

On the basis of the polarographic studies, the direct electron transfer polymerizations of the monomers, of which half-wave potentials could be measured, were conducted keeping the potential at a level where the monomer alone was reduced and the electrolyte was not affected. During the electrolysis of a-methyl-styrene, for example, the red color of the carbanion was observed around the cathode, but dissipacted and vanished quickly. Only low polymers were found in the cathodic compartment, but no polymer in the anolyte. In the polymerization of other monomers almost identical results were obtained. From the fact that tri-n-butyl-amine was detected in the catholyte and analysis of the end group of polymers obtained, two possible termination steps were postulated ... 

Many organic reagents have been used successfully in Pu separation processes. The reagents include tri- -butyl phosphate (TBP) methyl isobutyl ketone thenoyl trifluoroacetone (TTA) ethers, eg, diethyl ether, di- -butyl ether, tetraethylene glycol dibutyl ether trilaurylamine (TLA) tnoctyl amine (TOA) di- -butyl phosphate (DBP) hexyl-di(2-ethylhexyl) phosphate (HDEHP) and many others. Of these, TBP is by far the most widely used (30,95). 

An even more convincing argument is provided by the studies (46), results of which are also shown in Fig. 14. Tri-n-butyl amine in dimethyl formamide induces only a slow polymerisation of L-proline NCA whereas the polymerisation of y-ethyl-L-glutamate NCA is very fast under these conditions even if the concentration of the base is reduced by a factor of ten (78, 46). This is a striking observation since proline NCA is an extremely reactive monomer and polymerises very fast on addition of a primary amine. However, addition of 3-methyl hydantoin,... 

Over 35 years ago, Richard F. Heck found that olefins can insert into the metal-carbon bond of arylpalladium species generated from organomercury compounds [1], The carbopalladation of olefins, stoichiometric at first, was made catalytic by Tsutomu Mizoroki, who coupled aryl iodides with ethylene under high pressure, in the presence of palladium chloride and sodium carbonate to neutralize the hydroiodic acid formed (Scheme 1) [2], Shortly thereafter, Heck disclosed a more general and practical procedure for this transformation, using palladium acetate as the catalyst and tri-w-butyl amine as the base [3], After investigations on stoichiometric reactions by Fitton et al. [4], it was also Heck who introduced palladium phosphine complexes as catalysts, enabling the decisive extension of the ole-fination reaction to inexpensive aryl bromides [5],... 

The classical Heck reaction involves the Pd(0)-mediated coupling of alkenes with aryl and alkenyl halides at much more convenient laboratory conditions (Scheme 5.3). Hindered amines such as tri-n-butyl amine and triethyl amine are used as a base to neutralize HX produced as a by-product of the catalytic cycle. The Heck reaction has trans-selectivity. 

UDMH is known to be miscible with the following wafer, benzene, triethyl benzene, toluene, kerosene, ethyl alcohol, isobutyl alcohol, n-butyl ether, n-amyl ether, n-hexyl ether, diethyl ether, petroleum ether, petroleum naphtha, n-heptane, n-hexane, n-octane, n-decane, n-dodecane, n hexadecane, cyclohexane, 1,2-dimethyl cyclohexane, phenyl cyclohexane, n-tetradecane, trichloroethylene, dichloroethylene, perch oroethylene, 1,1,1 -t richloroe thane, tri-ethyl amine, ethylenediamine, diethylene triamine, acetonitrile, aniline, cumene, tetra-hydronaphtnaiene, tetraethylene pentamine, ethylene glycol and hydrazine (Ref 4)... 

C8H180 2,3,4-tri methyl-1 -pentanol 6570-88-3 195.24 11.494 2 15651 C8H19N N-isopropyl-N-methyl-tert-butyl amine 85523-00-8 200.00 19.497 2... 

The slight effect of solvent upon the rate of decomposition is characteristic of tertiary dialkyl peroxides. For example, the rate of decomposition of di-r-butyl peroxide is altered only slightly by changing from the gas phase through hydrocarbon solvents to tri-n-butyl amine (Table 66). These results indicate that there is little ionic character in the activated complex of the rate-determining step (2). 

Tris-[3-mcthyl-butyl]-amin (2) 30 Min > 3-Methyl-butanal 84%... 

Methylenation. 2-(Phenylthio)ethanols (2), prepared from ketones (1) and phenylthiomethylhthium, undergo reductive /3-ehmination to give 1-alkenes when treated with the black reagent prepared from TiCU and L1A1H4 in the presence of a tertiary amine [ 1,8-bis(dimethylamino)naphthalene or tri-n-butyl-amine]. Benzene-dioxane is used as solvent for the elimination (4 hr. reflux). ... 

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