Transient ischemia

OA were aborted in 2003 due to the development of mild to moderate liver fibrosis in dogs treated for 9 months with high doses of pralnacasan. This was in spite of recent evidence demonstrating the effectiveness of pralnacasan treatment in the acute dextran sulfate sodium (DSS)-induced colitis model, which resembles Crohn s disease (CD) characteristics, and in transient ischemia induced brain damage. [Pg.333]

Reduction of the risk of transient ischemic attacks or strokes in men who have had transient ischemia of the brain due to fibrin platelet emboli (aspirin only). This use has been found to be effective only in men (not women). [Pg.151]

Nowak, T.S., Bond, U., Schlesinger, M.J. (1990). Heat shock levels in brain and other tissues after hyperthermia and transient ischemia. J. Neurochem. 54,451-458. [Pg.458]

Lou M, Eschenfelder CC, Herdegen T, Brecht S, Deuschl G. Therapeutic window for use of hyperbaric oxygenation in focal transient ischemia in rats. Stroke 2004 35 578-583. [Pg.120]

Kirino T, Sano K. 1984. Selective vulnerability in the gerbil hippocampus following transient ischemia. Acta Neuropathol 62 201-208. [Pg.189]

Proteasome Transient ischemia Decreased activity of 26S proteasome 410, 411... [Pg.738]

Aspirin Aspirin, for reducing the risk of recurrent transient ischemic attacks (TIAs) or stroke in men who have had transient ischemia of the brain because of fibrin platelet emboli. It has not been effective in women and is of no benefit for completed strokes. [Pg.909]

Hashimoto, E., Ogita, T., Nakaoka, T., Matsuoka, R., Takao, A., and Kira, Y. 1994. Rapid induction of vascular endothelial growth factor expression by transient ischemia in rat heart. Am. J. Physiol. 267 H1948-H1954. [Pg.320]

Haba K., OgawaN., Mizukawa K., and Mori A. (1991). Time course of changes in lipid peroxidation, pre- and postsynaptic cholinergic indices, NMDA receptor binding and neuronal death in the gerbil hippocampus following transient ischemia. Brain Res. 540 116-122. [Pg.194]

PCI, with larger increases occurring in patients without collateral vessels (4.8% with vs. 14% without) [13]. Although these studies indicate that IMA is an early marker of transient ischemia in the PTCA setting, larger trials are necessary to validate this hypothesis. [Pg.7]

Iwai M, Sato K, Omori N, Nagano I, Manabe Y, Shoji M, Abe K (2002) Three steps of neural stem cells development in gerbil dentate gyrus after transient ischemia. J Cereb Blood Flow Metab 22 411-419... [Pg.100]

Kohda Y, Yamashima T, Sakuda K, Yamashita J, Ueno T, Kominami E, Yoshioka T (1996) Dynamic changes of cathepsins B and L expression in the monkey hippocampus after transient ischemia. Biochem Biophys Res Commun 228 616-622 Kohwi M, Osumi N, Rubenstein JL, Alvarez-Buylla A (2005) Pax6 is required for making specific subpopulations of granule and periglomerular neurons in the olfactory bulb. J Neurosci 25 6997-7003... [Pg.101]

Primate neurons show different vulnerability to transient ischemia and response to cathepsin inhibition. Acta Neuropathol (Berl) 104 267-272... [Pg.106]

Nucci, C., Tartaglione, R., Cerulli, A., Mancino, R., Spano, A., Cavaliere, F., Rombola, L., Bagetta, G., Corasaniti, M. T., and Morrone, L. A. (2007). Retinal damage caused by high intraocular pressure-induced transient ischemia is prevented by coenzyme Q,10 in rat. Int. Rev. Neurobiol. 82, 397-406. [Pg.422]

Retinal Damage Caused by High Intraocular Pressure-Induced Transient Ischemia is Prevented by Coenzyme Q10 in Rat... [Pg.462]

Suyama K, Saito K, Chen G, Pan PS, Manji HK, Potter WZ. 1995. Alterations in cyclic AMP generation and G-protein subunits following transient ischemia in gerbil hippocampus. J Cereb Blood Flow Metab 15 877-885. [Pg.26]

Sandhu, R., Diaz, R.J., Mao, G.D., and Wilson, G.J. 1997. Ischemic preconditioning differences in protection and susceptibility to blockade with single-cycle versus multicycle transient ischemia. Circulation 96 984-995. [Pg.86]

Hamberg LM, Macfarlane R, Tasdemiroglu E et al (1994) Measurement of cerebrovascular changes in cats after transient ischemia using dynamic magnetic resonance imaging. Stroke 24 444-450... [Pg.114]

Uyama O, Okamura N, Yanase M, Narita M, Kawabata K, Sugita M (1988) Quantitative evaluation of vascular permeability in the gerbil brain after transient ischemia using Evans blue fluorescence. J Cereb Blood Flow Metab 8 282-284... [Pg.147]

Globus M. Y., Busto R., Dietrich W. D., Martinez E., Valdes I., and Ginsberg M. D. (1989) Direct evidence for acute and massive norepinephrine release in the hippocampus during transient ischemia. J. Cereb. BloodFlow Metab. 9,892-896. [Pg.36]

Similarly, Schmid-Elsaesser et al. (7) reported a synergistic effect of hypothermia when added to therapy with either tirilizad or magnesium (Mg). In this study, rats were subjected to transient ischemia of 90 min duration using a suture occlusion model. Hypothermia was administered intraischemically and animals were rewarmed simultaneous with reperfusion. Subjects were treated with various combinations of the three agents, in a systematic fashion. A stepwise increase in the reduction in infarct volume was observed between Tirilizad + Mg, hypothermia alone, and hypothermia + tirilizad + Mg in combination. [Pg.97]

C. Depre, J. Tomlinson, R.K. Kudej, V. Gaussin, E. Thompson, S.J. kim, D. Vatner, J. Topper and S. Vatner, Gene program for cardiac cell survival induced by transient ischemia in conscious pig, Proc. Nall. Acad Sci. USA. 98, 9336-9341 (2001). [Pg.68]

I. Sheiban, S. Tonni, P. Benussi, A. Marini, G.P. Trevi, Left ventricular dysfunction following transient ischemia induced by transluminal coronary angioplasty, Eur Heart J 4, (Suppl A) 14-21 (1993). [Pg.190]

Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...