Tocopherol nicotinate

Tocopherol nicotinate/Juvela N Soft capsules/Eisai Co./ hypertension, hyper lipidemia... 

Tocopherol nicotinate/ Juvela N Soft capsules/ Eisai Co./ Hypertension, hyper-lipidemia CHj j CHj CHj CHj 200 mg (1 capsule) t.i.d. Soft gelatin capsule 200 mg Medium-chain triglycerides Glycol esters of fatty acid Aspartic acid ... 

Wehmeyer et al. (1969) published results on the content of B vitamins (thiamine, riboflavin, and nicotinic acid), vitamin C, and p-carotene and foimd that the morama bean is a good source of both B vitamins and vitamin C, but a poor source of p-carotene. Holse et al. (2010) investigated the content of the eight vitamin E isomers and found that the vitamin E composition in morama beans is dominated by y-tocopherol with 59-234 ng/g, followed by a- and p-tocopherols with 14- 8 gg/g and 1.1-3.3 ng/g, respectively. Eurthermore, traces of 8-tocopherol as well as p- and y-tocotrienols were present in some samples. The remaining two tocotrienols (a- and 8-) were not present in the beans. The presence of a-, p-, and y-tocopherols in the morama bean was also foimd by Mitei et al. (2009) who examined morama oil and by Dubois et al. (1995) who examined two samples of T.fassoglense. 

Zondlo Fiume, M., Final report on the safety assessment of tocopherol, tocopheryl acetate, tocopheryl linoleate, tocopheryl linoleate/oleate, tocopheryl nicotinate, tocopheryl succinate, dioleyl tocopheryl methylsilanol, potassium ascorbyl tocopheryl phosphate, and tocophersolan, Int. J. Toxicol., 21 (suppl 3), 51,2002. 

To inhibit Aj8 aggregation into amyloid is to prevent misfolding of soluble AjS. Once the misfoldingtook place the aggregation is only a matter of time and far more difficult to control (174). So far only nicotine (30,Fig. 13.9) and melatonin (31)appear to be affecting the conformation of soluble AjS (175-177). Antioxidants, such as antituberculosis antibiotic ri-fampicin (32) or a-tocopherol, were reported to inhibit aggregation and neurotoxicity of AjS in vitro (178-180). A monoamine oxidase inhibitor, selegiline (33, Fig. 13.9), may also be... 

D-a Tocopheryl linoleate DL-a Tocopheryl linoleate. See Tocopheryl linoleate Tocopheryl nicotinate CAS 16676-75-8 43119-47-7 51898-34-1 EINECS/ELINCS 256-101-7 257-501-4 Synonyms 3-Pyridinecarboxylic acid, 3,4-d i hyd ro-2,5,7,8-tetramet hy I -2-(4,8,12-trimethyltridecyl)-2H-1 -benzopyran-6-yl ester D-a Tocopheryl nicotinate DL-a Tocopheryl nicotinate Vitamin E nicotinate Definition Ester of tocopherol and nicotinic acid Empiricai CssHssNOs Uses Antioxidant in cosmetics Manuf./Distrib. BASF http //www.basf.com Trade Name Synonyms Vitamin E Nicotinate C t[BASF http //www.basf.com]... 

R,4 R,8 R-a-Tocopheryl nicotinate. Seed-a-Tocopheryl nicotinate d-a-Tocopheryl nicotinate Synonyms 2,5,7,8-Tetramethyl-2-(4, 8, 12 -trimethyltridecyl)-6-chromanol-3-carboxypyridine 2R,4 R,8 R-a-Tocopheryl nicotinate Vitamin E nicotinate Definition Ester of tocopherol and nicotinic acid Empiricai C35H53NO3... 

Thiosalicylic acid Thioxanthine Tocopherol D-a-Tocopherol DL-a-Tocopherol Tocophersolan Tocopheryl acetate d-a-Tocopheryl acetate dl-a-Tocopheryl acetate Tocopheryl linoleate Tocopheryl nicotinate d-a-Tocopheryl nicotinate Tocopheryl succinate o-Tolyl biguanide Triethyl citrate Tris (nonylphenyl) phosphite... 

Unamino L-CSTE 200-193-3 Nicotine 200-194-9 DL-a-Tryptophan 200-198-0 Sodium salicylate 200-201-5 (+)-y-Tocopherol 200-208-3... 

Vitamins are organic compounds required as vital nutrients in small amounts by a given organism. Vitamins cannot be synthesized in sufficient quantities by the body and have to be provided with the diet to avoid characteristic diseases (e.g., scurvy in the case of human shortage of vitamin C). The three most important vitamins (by their industrial production capacities) are vitamin C, vitamin B3 (nicotinic acid amide) and vitamin E (tocopherol). These three vitamins represent, from their stmcture and synthesis, typical fine chemicals. However, they are produced on a multi-10000 ton-scale per year. To give an example that also fulfils the capacity criterion of fine chemicals. Table 5.3.19, shows vitamin B2 (riboflavin). The latter is produced both by chemical synthesis and fermentation on the order of 10 000 tons yr . Riboflavin is required for a wide variety of cellular processes and is used for therapeutic purposes and as food additive. 

Abbreviations a-T, 3-T, y-T, 5-T a-, 3-, y-, 5-tocopherol a-T3, P-T3, y-T3, 5-T3 a-, P-, y-, 5-tocotrienol a-TA a-tocopheryl acetate a-TQ a-tocopherolquinone a-TN a-tocopheryl nicotinate 5,7-T 5,7-dimethyltocol PMC 2,2,5,7,8-pentamethyl-6-hydroxychroman G gradient elution. Special eluent compositions 1 methanol-t-butyl methyl ether-water 2 acetonitrile-water-tetrahydrofuran 3 acetonitrile-chloroform-isopropanol-water 4 acetonitrile-methanol-dichloromethane-water. 

Staining Applications Brain spinal cord bacteria chromosomes nicotinic acetylcholine receptor nucleic acids phosphates polyphosphates tocopherol tocopherol acetate ... 

Most vitamin E supplements and food fortificants contain all rac-a-tocopherol, but can contain mixtures of tocopherols or tocotrienols. Supplements often are sold as esters, which protect a-tocopherol from oxidation. These can be acetates, succinates, or nicotinates of a-tocopherol. Either the natural stereoisomer (RRR-a-tocopherol) or the synthetic all rac-a-tocopherol) can be sold as an ester, e.g., d- or d/-a-tocopheryl acetate, respectively. 

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