Titanium endothelial cells

Other applications use self-assembling fibers to coat materials. For example, preassembled peptide amphiphiles have been covalently immobilized on titanium implant surfaces via a silane layer (Sargeant et al., 2008). Primary bovine artery endothelial cells or mouse calvarial preosteoblastic cells spread on these coated surface and proliferated to a far greater extent than on samples where the peptide amphiphiles had been drop cast onto the metal surface. This study therefore suggests that covalent attachment is required in order to prevent fibers lifting from the coated surface and to encourage maximal cell growth. 

Xue, X., Wang, J., Zhu, Y., Tu, Q., Huang, N., 2010. BiocompatibiUty of pure titanium modified by human endothelial cell-derived extraceUular matrix. Appl. Surf. Sci. 256, 3866-3873. 

Pan CJ, Hou YH, Zhang BB, Dong YX, Ding HY. Blood compatibility and interaction with endothelial cells of titanium modified by sequential immobihzation of poly(eth-ylene glycol) and heparin. J Mater Chem 2014 2 892-902. 

Biopsy specimens from 17 mandibular fracture sites treated by open reduction with titanium in 12 patients showed doublelayered connective tissue, which consisted of dense fibrous connective tissue and relatively loose connective tissue containing proliferated blood vessels with hypertrophied endothelial cells [78 ]. The vascular endothelial cells expressed HLA-DR, CD54, and CD62P antigens in some cases they were CD62E-positive. CD68-positive, and CDllc-positive round or spindle-shaped macrophages had infiltrated around the small vessels and contained fine cytoplasmic titanium particles. In some cases CD4- - and CD8-y T lymphocytes had infiltrated around venules. 

N. Ozkucur, C. Wetzel, F. Hollstein, E. Richter, R.H. Funk, T.K. Monsees, Physical vapor deposition of zirconium or titanium thin films on flexible polyurethane highly support adhesion and physiology of human endothelial cells, J. Biomed. Mater. Res. Part A 89 (2009) 57-67. 

Choudhary, S., M. Berhe, K. M. Haberstroh, and T. J. Webster. 2006. Increased endothelial and vascular smooth muscle cell adhesion on nanostructured titanium and CoCrMo. Int J Nanomed 1(1) 41-9. 

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