Thermo Fisher Scientific

The following protocol is based on the published methods as well as the specific instructions provided with the heavy atom crosslinkers from Thermo Fisher Scientific. For new applications, the amount of crosslinkers added to the sample will have to be optimized to obtain useful information about the interactions. 

Pierce Biotechnology, Thermo Fisher Scientific, Rockford, Illinois, USA... 

Figure 5.5 Examples of specifications for three grades of n-hexane (a) Fisher Distol F (b) Fisher Certified HPLC (c) Fisher Certified AR Reproduced by permission of Thermo Fisher Scientific Ltd.

FIGURE 5.2 Ion path for LTQ-Orbitrap. (Courtesy of Thermo Fisher Scientific, Waltham, Massachusetts.)... 

Figure 2.2 Microarray slides (Photo courtesy of Thermo Fisher Scientific).

Thermo Fisher Scientific 5344 John Lucas Drive Burlington, Ontario L7L 6A6 Canada... 

Thermo Fisher Scientific, USA (formerly Fisher Scientific and Thermo Electron). The number one company in this field [sales > 9 billion (2007,E)] supplies biochemicals and bioreagents organic and inorganic chemicals (of which >15,000 fine organic chemicals) sera cell culture media sterile liquid-handling systems microbiology media and related products scientific consumable products, instruments, and equipment. 

Liquid chromatography/mass spectrometry analyses were performed with an ion trap mass spectrometer (LCQ, Thermo Fisher Scientific Inc., MA) equipped with an HPLC system (Agilent, CA Model 1100) connected with a diode-array detector (DAD, G1315A). The sample solution (1-5 p,L) was applied on an Inertsil ODS-3 column (2.1 x 150 mm, 3 p,m, GL... 

An automated method can be run after validation using multiparametric open analysers [1, 11, 17], For example, KONELAB 30 (Thermo Fisher Scientific, Waltham, USA). There is no standard for pyruvate, ACAC or . The results are calculated taking into account the molecular extinction coefficient of NADH (6.3 mmol 1 cm 1). A lactate standard is provided in the kit. 

Figure 2.11 Sensitivity for selected long-lived radionuclides measured by ICP-SFMS (Element, Thermo Fisher Scientific) with (yellow) and without (green) shielded torch (CE - guard electrode). (]. S. Becker and H. ). Dietze. Int. ). Mass Spectrom. Ion Proc. 197, 1-35 (2000). Reproduced by permission of Elsevier.)...

Figure 4.4 Schematic (a) and photograph of ion detector with extended dynamic range (b) in the double-focusing sector field mass spectrometer Element. (Reproduced by permission of Thermo Fisher Scientific, Bremen.)...

Figure 5.1 Main parts of an inductively coupled plasma mass spectrometer sample introduction systems (left column), e.g., Meinhard or MicroMist nebulizer with cyclonic spray chamber, ultrasonic nebulizer, microconcentric nebulizer and laser ablation system (all from CETAC Technologies), ion source (middle column) and several types of mass spectrometers, (a) Agilent 7500 from Agilent, (b) Platform from CV Instruments, or (c) Element from Thermo Fisher Scientific. (Parts of this figure were reproduced with permission from CETAC Technologies, Agilent, CV Instruments and Thermo Tisher Scientific, respectively.)...

In addition to these collision/reaction cell instruments, since 2002 Thermo Fisher Scientific has been selling the XSeries ICP-MS with a hexapole collision cell (developed from ThermoElemental PQExel ICP-MS) as a bench top instrument on the analytical market. A special ion extraction system in Thermo s XSeries", ion optics together with a hexapole collision cell to minimize the interference problem in ICP-MS, provides the lowest background signals for ICP-QMS (< 0.5 cps). 

Agilent Perkin Elmer Sciex Thermo Fisher Scientific Varian... 

At present, the Nu Plasma from Nu Instruments, Wrexham, UK, the Isoprobe from GV Instruments, Manchester, UK, and the Neptune from Thermo Fisher Scientific, Bremen, Germany, are the most precise multiple ion collector ICP mass spectrometers available on the analytical market. 

Figure 5.12 MC-ICP-MS a) Plasma 54 (with called S configuration ), from VC Elemental (M. E. Wieser and]. B. Schwieters, Int. /. Mass Spectrom., 242, 97 (2005). Reproduced by permission of Elsevier), b) Nu Plasma from Nu instruments (Reproduced by permission of NU Instruments Ltd) c) Isoprobe from CV Instruments (Reproduced by permission of CV Instruments Ltd) d) Neptune from Thermo Fisher Scientific (Reproduced by permission of Thermo Fisher Scientific, Bremen) e) Nu 1700 (Reproduced by permission of NU Instruments Ltd).

Element, Thermo Fisher Scientific Nu Plasma, Nu Instruments NEPTUNE, Thermo Fisher Scientific Isoprobe, VG Instruments... 

Aridus, USN operated in the continuous mode versus the DS-5 nebulizer used in the flow injection mode) for solution introduction in 1CP-SFMS (Element, Thermo Fisher Scientific, Bremen) for uranium determination in aqueous solution75 are summarized in Table 5.3. 

Table 5.3 Characteristics of ICP-SFMS (Element, Thermo Fisher Scientific,...

The experimental arrangement of LA-ICP-MS using a powerful laser ablation system coupled to a double-focusing sector field ICP-MS (Element, Thermo Fisher Scientific, Bremen) is shown in Figure 5.22. A cooled laser ablation chamber using two Peltier elements in serial connection... 

Figure 5.22 Schematic of laser ablation inductively coupled plasma mass spectrometer a laser ablation system (wa velength 213 nm) is coupled to a double-focusing sector field ICP-MS (Element, Thermo Fisher Scientific, Bremen). The cooled laser ablation chamber using two Peltier elements was developed in the author s laboratoryJ26 (M. V. Zoriy, M. Kayser, A. Izmer, C. Pickhardt and J. S. Becker, Int. J. Mass Spectrom., 242, 297 (2005). Reproduced by permission of Elsevier.)...

A GD mass spectrometer from Thermo Fisher Scientific with a direct current (dc) glow discharge ion source based on the mass spectrometric arrangement of the Element (Element GD) has been available on the analytical market since 2005 for sensitive multi-element analysis of trace impurities in conducting samples. The experimental arrangement of the dc GD ion source (Grimm type) and... 

Figure 5.29 Instrumental setup of a radiofrequency (rf) glow discharge mass spectrometer by combining an ion source developed in house with a commercial double-focusing sector field mass spectrometer with reverse Nier-Johnson geometry (Element, Thermo Fisher Scientific, Bremen, Germany), (f S. Becker et al., IntJ. Mass Spectrom., 164, 81 (1997). Produced by permission of Elsevier.)...

Figure 6.5a illustrates part of a real mass spectrum of a radioactive waste solution in the mass range 180-250 u measured by double-focusing sector field ICP-MS (ELEMENT, Thermo Fisher Scientific) at low mass resolution. In this mass spectrum, atomic ions of Re at mass 185 u and 187 u with isotope abundances of 37.4 % and 62.6 %, respectively (Re was used for "Tc precipitation),... 

---