Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Tau hyperphosphorylation

Saez ET, Pehar M, Vargas MR, Barbeito L, Maccioni RB (2006) Production of nerve growth factor by beta-amyloid-stimulated astrocytes induces p75NTR-dependent tau hyperphosphorylation in cultured hippocampal neurons. J Neurosci Res 84 1098-1106 Sala C, Roussignol G, Meldolesi J, Fagni L (2005) Key role of the postsynaptic density scaffold proteins Shank and Homer in the functional architecture of Ca homeostasis at dendritic spines in hippocampal neurons. J Neurosci 25 4587 592 Santello M, Volterra A (2008) Synaptic modulation by astrocytes via Ca(2-l-)-dependent glutamate release. Neuroscience 158 253-9... [Pg.298]

AP amyloid neuritic plaques CAA cerebral amyloid angiopathy DG Dentate gyrus DP diffuse (preamyloid) plaques NFT neurofibrillar tangles NR not reported P-Tau hyperphosphorylated MAPT tau protein. [Pg.55]

Zhou XW, Gustafsson JA, Tanila H, Bjorkdahl C, Liu R, Winblad B, Pei JJ (2008a) Tau hyperphosphorylation correlates with reduced methylation of protein phosphatase 2A. Neutobiol Dis 31(3) 386-394... [Pg.630]

The mechanisms that govern apoE toxicity in the brain are not fully understood. Some proposed mechanisms include isoform specific toxicity, apoE E4-mediated amyloid aggregation, and apoE E4-mediated tau hyperphosphorylation (Huang,... [Pg.708]

Yang Y, Zhang J, Ma D, Zhang M, Hu S, Shao S et al (2013) Subcutaneous administration of liraglutide ameliorates Alzheimer-associated tau hyperphosphorylation in rats with Type 2 Diabetes. J Alzheimers Dis 37(3) 637-648... [Pg.542]

Geekiyanage H, Upadhye A, Chan C (2013) Inhibition of serine palmitoyltransferase reduces A(1 and tau hyperphosphorylation in a murine model A safe therapeutic strategy for Alzheimer s disease. Neurobiol Aging 34 2037-2051... [Pg.550]

Tau binds Cu [176], which is enriched in NETs [16,79]. Recent data indicates that oxidative stress both in cell culture and in SOD2 knockout mice induces tau hyperphosphorylation (Eig. 2). A model emerges where corruption and accumulation of Ab decorated with Cu " " generates hydrogen peroxide and oxidative stress leading to the hyperphosphorylation of tau, and subsequent NET formation. Recent reports have indicated that both Zn and Fe(III) induce aggregation of hyperphosphorylated tau [177] while reduction of Fe (III) to Fe (II) reverses tau aggregation [178]. [Pg.123]


See other pages where Tau hyperphosphorylation is mentioned: [Pg.323]    [Pg.325]    [Pg.326]    [Pg.28]    [Pg.246]    [Pg.249]    [Pg.263]    [Pg.268]    [Pg.126]    [Pg.36]    [Pg.603]    [Pg.612]    [Pg.650]    [Pg.660]    [Pg.665]    [Pg.636]    [Pg.636]    [Pg.2074]    [Pg.406]    [Pg.419]    [Pg.420]    [Pg.427]    [Pg.435]    [Pg.437]    [Pg.442]    [Pg.467]    [Pg.14]    [Pg.96]    [Pg.141]    [Pg.143]    [Pg.148]    [Pg.84]    [Pg.291]    [Pg.291]    [Pg.60]    [Pg.19]    [Pg.322]    [Pg.381]    [Pg.84]    [Pg.493]    [Pg.497]    [Pg.498]   
See also in sourсe #XX -- [ Pg.264 ]




SEARCH



Hyperphosphorylation, tau protein

© 2024 chempedia.info