Suffix amide

Amides. For primary amides the suffix -amide is added to the systematic name of the parent acid. For example, CH3—CO—NHj is acetamide. Oxamide is retained for HjN—CO—CO—NHj. The name -carboxylic acid is replaced by -carboxamide. 

For amino acids having trivial names ending in -ine, the suffix -amide is added after the name of the acid (with elision of e for monoamides). For example, HjN—CHj—CO—NHj is glycin-amide. 

Step 2 Replace the -oic acid ending of the name of the parent acid with the suffix -amide. 

Amides are named by replacing the -oic acid or -ic acid suffix of the parent carboxylic acids with the suffix -amide, or hy replacing the -carboxylic acid ending with -carboxamide. Alkyl groups on nitrogen atoms are named as substituents, and are prefaced by N-or N,N-, followed by the name(s) of the alkyl group(s). 

The IUPAC rules name amides by appending the suffix -amide to the parent name of the carboxylic acid from which the amide is derived. If there are substituents on the amide nitrogen, they are given the locant N. Three examples are given in Figure 11.56. 

To name a primary amide, first name the corresponding acid. Drop the -ic acid or -oic acid suffix, and add the suffix -amide. For secondary and tertiary amides, treat the alkyl groups on nitrogen as substituents, and specify their position by the prefix N-. 

All 1 ° amides are named by replacing the -ic acid, -oic acid, or -ylic acid ending with the suffix amide. 

In amides, the amino group is directly bonded to the carbonyl group. Amide nomenclature includes the simple suffix -amide. In secondary and tertiary amides, the substituents that are bound to the nitrogen atom are not labeled by the number, but by the letter N. The representative examples are A-methylmethanamide or N,N- dimethylmethanamide in the above scheme. Some amides which are derivatives of formic or of acetic acids also bear traditional names as formamide or acetamide. 

As is thus clear from these few examples, the names of amides can be considered to be derived from those of the parent alkanes, alkenes, and so on, by simply removing the final e and replacing it with the suffix amide. Alternatively, reinforcing their relationship to carboxylic adds, the names of amides can be considered to be derived from those of the corresponding carboxylic acids by removing the suffix oic and the added word acid and replacing them by the suffix amide. ... 

As when we name carboxylic acids, the carbon atom of the amide group is counted when assessing the longest unbranched chain present, and as such is counted as the first in the chain. Thus amides are named after the longest carbon chain, followed by the suffix -amide. Figure 10.34 shows the structures of ethanamide (see also Figure 10.35 overleaf) and 2 methylpropanamide. 

Step [2] Name the acyl group (RCO-) with the suffix -amide. 

Change the -ic acid or -o/c acid suffix of the parent carboxylic acid to the suffix -amide. 

In both the lUPAC and common names, amides are named by dropping the ic acid or oic acid from the carboxylic acid name (lUPAC or common), and adding the suffix amide. We can diagram the name of an amide in the following way ... 

An amide is an organic compound in which the -OH group of a carboxylic acid is replaced by a nitrogen atom bonded to other atoms. Amide structures are found in proteins. Amides are named by writing the name of the alkane that has the same number of carbon atoms and replacing the final -e with the suffix -amide. 

Acid derivatives include carboxylic acids, RC(=0)0H, suffix -oic acid, esters RC(=0)0R, suffix -oate amides, R(C=0)NH2 or RC(=0)NR 2, suffix, -amide, acid chlorides, RC(=0)CI, suffix -oyl chloride anhydrides RC(=0)0C(=0)R, suffix -oic anhydride. 

The name of an amide is constructed from the alkane part of the acid name and the suffix -amide is added. If hydrogen atoms on the nitrogen atom are replaced with other groups, then a substituted amide is obtained. For example, in the molecules below, one or both of the FI atoms in the —NFl2 group of ethanamide have been replaced by other groups. Flere are a few examples. 

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