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Staphylococcus aureus antibiotics active against

PlusbasinAj 20 Pseudomonas sp. [57] Antibiotic activity against methicillin-resistant Staphylococcus aureus and active against Van A-type vancomycin-resistant enterococci [58] VanNieuwenhze [59]... [Pg.324]

Recently, the piperazine intermediate 15 for the total synthesis of (—)-lemon-omycin (9) was reported by Fukuyama et al. [14], (—)-Lemonomycin possesses interesting antibiotic activity against methiciUin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecium, as well as cytotoxicity against the human colon tumor cell line HCT-116 [15]. The reaction of 2-isocyanoethyl phenyl carbonate 11 gave Ugi product 14, which was further transformed to a piperazine intermediate 15 (Scheme 2). [Pg.89]

Celenamide E (108), a tripeptide alkaloid from the Patagonian sponge Cliona chilensis, shows antibiotic activity against Bacillus subtilis, Staphylococcus aureus, Micrococcus luteus, and Enterococcus faecalis at 50 pg/disk. An unusual feature is the presence of a N-terminal dehydroamino acid [87]. [Pg.778]

Staphylococcus aureus - [ANTIBIOTICS - BETA-LACTAMS - CEPHALOSPORINS] (Vol 3) - [DISINFECTANTS AND ANTISEPTICS] (Vol 8) - [ANTIBIOTICS - BETA-LACTAMS - BETA-LACTAMASE INHIBITORS] (Vol 3) - [ANTIBIOTICS - LINCOSAMINIDES] (Vol3) - [ANTIBIOTICS - BETA-LACTAMS - PENICILLINS AND OTHERS] (Vol 3) - [ANTIBIOTICS-AMINOGLYCOSIDES] (Vol2) - [ANTIBIOTICS - GLYCOPEPTIDES(DALBAHEPTIDES)] (Vol 2) -bacitracin resistance [ANTIBIOTICS - PEPTIDES] (Vol 3) -ethanol activity against [DISINFECTANTS AND ANTISEPTICS] (Vol 8) -inhibited by sorbates [SORBIC ACID] (Vol 22)... [Pg.926]

There was some antibiotic activity against Staphylococcus aureus. Streptococcus jecalis. Bacillus subtilis, Escherichia coli and Mycobacterium phlei (28). [Pg.74]

Aeroplysinin-1 (852), a metabolite of marine organisms, shows antibiotic activity against Staphylococcus aureus and antileukemia activity against L-1210. This metabolite was synthesized by Pb(OAc)4-mediated phenolic oxidation as a key step. Here, 3,5-dibromo-2-hydroxy-4-methoxyphenylacetonitrile (853) was oxidized with excess of Pb(OAc)4 in AcOH to give in 35% yield the desired cyclohexa-2,4-dienone 854, which was converted to the target molecule in 2 steps. [Pg.1327]

The new compounds (203-205) and the derivatives 206-208 were assayed for antimicrobial activity. Compounds 203-205 showed antibiotic activity against B. subtilis with a MICs of 12-14, 35-39 and 25 xg/ml, respectively 203 was also active against Staphylococcus aureus (MIC 40-50 xg/ml). These results suggest that the antibiotic activity may be associated with the presence of free hydroxyl groups in ring A compound... [Pg.718]

Ibberine. Metabolite from Haplophyllum tuberculatum (Rutaceae) (aerial parts) with antibiotic activity against Staphylococcus aureus and Escherichia colt... [Pg.671]

Belofsky G, Carreno R, Lewis K, Ball A, Casadei G, Tegos GP (2006) Metabolites of the smoke tree , Dalea spinosa, potentiate antibiotic activity against multidrug-resistemt Staphylococcus aureus. J Nat Prod 69 261-264... [Pg.199]

Brumfitt, W., Salton, M.R.J., and Hamilton-Miller, J.M.T. (2002). Nisin alone and combined with peptidoglycan-moduling antibiotics activity against methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci. J Anticrobiol Chemother Sd, 731—734. [Pg.94]

The vinyl ketone partner used in the CM reaction can be of a size comparable to that of the other partner. For example, Cossy et al. recently described the synthesis of the monomeric counterpart of marinomycin A, isolated from the saHne culture of Marinospora strain CNQ-140, which shows significant antibiotic activity against Staphylococcus aureus or Enterococcus faecium, using a CM between a vinyl ketone and a type I olefin [14]. Another case of CM between a complex vinyl ketone and a type 1 olefin was reported by Rychnovsky and coworkers for the construction of the C1-C52 segment of amphidinol 3 [15],... [Pg.292]

Tolypomycin Y (48) shows strong antibacterial activity against gram-positive bacteria and Neisseriagonorrheae. When adininistered by subcutaneous, intraperitoneal, and intravenous routes, tolypomycin Y is effective in mice infected with Staphylococcus aureus Streptococcuspyrogenes and Diplococcuspneumoniae. Cross-resistance is observed with rifampicia but not with other antibiotics. Resistance to tolypomycin Y develops rapidly. The bioactivity of tolypomycin R... [Pg.499]

Oral, narrow-spectrum antibiotic therapy with activity against Staphylococcus aureus and streptococcal species. Include coverage for MRSA (HA- or CA-MRSA) according to patient history and resistance patterns in the area. [Pg.1083]

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See also in sourсe #XX -- [ Pg.5 , Pg.631 ]



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