Sorbitan sesquioleate

Sorbitan sesquioleate emulsions of petrolatum and wax are used as ointment vehicles in skin treatment. In topical appHcations, the inclusion of both sorbitan fatty esters and their poly(oxyethylene) derivatives modifies the rate of release and promotes the absorption of antibiotics, antiseptics, local anesthetics, vasoconstrictors, and other medications from suppositories, ointments, and lotions. Poly(oxyethylene(20)) sorbitan monooleate, also known as Polysorbate 80 (USP 23), has been used to promote absorption of ingested fats from the intestine (245). 

Bacitracin zinc polymyxin B sulfate Polysporin Propylene glycol, sorbitan sesquioleate, and white petrolatum... 

The thickness of horizontal filns of n-decane sandwiched between two water (or aqueous electrolyte) droplets has been determined by a light reflectance technique. The films were stabilised by three surfactants an xyx block copolymer of poly(ethyleneoxide) and poly(12-hydroxystearic) acid soya bean lecithin Arlacel 83 (sorbitan sesquioleate). Results obtained for two and three component mixtures of the surfactants were compared with those for the single surfactants. The results showed that, provided sufficient polymer is present in the film, the thickness is determined by the longest oleophilic chain, namely the poly(12-hydroxystearic) acid. 

The structures of the two monomeric surfactants used in this work, 1,4 sorbitan sesquioleate (Arlacel 83) and L,o-dipalmitoyl phosphatidyl choline, used in the impure form of soya bean lecithin, are very different from the block copolymer Bl both can be considered to be V-shaped and about 3 nm in overall length. A comparison of the film thicknesses obtained for the three surfactants is given in Table V. The film thickness for sorbitan sesquioleate is... 

Table VI gives a comparison of the sorbitan sesquioleate film...

Stable, thinner films approximately equal in thickness to that of the sorbitan sesquioleate single-component film (about 6 nm) ... 

Equilibrium thickness of Arlacel 83 soya bean lecithin mixed films in n-decane at 25°C. Total surfactant concentration = 5 g dm- aqueous phase water. Ordinate h/nm Abscissa mol fraction sorbitan sesquioleate. 

An emulsion liquid membrane (ELM) system has been studied for the selective separation of metals. This system is a multiple phase emulsion, water-in-oil-in-water (W/O/W) emulsion. In this system, the metal ions in the external water are moved into the internal water phase, as shown in Fig. 3.4. The property of the ELM system is useful to prepare size-controlled aiKl morphology controlled fine particles such as metals, carbonates/ and oxalates.Rare earth oxalate particles have been prepared using this system, consisting of Span83 (sorbitan sesquioleate) as a surfactant and EHPNA (2-ethyl-hexylphospholic acid mono-2-ethylhexyl ester) as an extractant. In the case of cerium, well-defined and spherical oxalate particles, 20 - 60 nm in size, are obtained. The control of the particle size is feasible by the control of the feed rare earth metal concentration and the size of the internal droplets. Formation of ceria particles are attained by calcination of the oxalate particles at 1073 K, though it brings about some construction of the particles probably caused by carbon dioxide elimination. 

Sorbitan sesquioleate Base, emulsifying agent, solubilizing agent, stabilizer, surfactant, vehicle iv, im... 

Sorbitan laurate Sorbitan oleate Sorbitan palmitate Sorbitan stearate Sorbitan trioleate Sorbitan sesquioleate Sorbitani lauras Sorbitani okas Sorbitani palmitas Sorbitani sesquioleas Sorbitani stearas Sorbitani trioleas... 

Sorbitan monooleate Sorbitan monopalmitate Sorbitan monostearate Sorbitan sesquioleate Sorbitan trioleate... 

Sobitan monolaurate Sorbitan monooleate Sorbitan sesquioleate Sorbitan trioleate Peroxide value... 

Sorbitan monolaurate Sorbitan monooleate Sorbitan monopalmitate Sorbitan monostearate Sorbitan sesquioleate Sorbitan trioleate Saponification value Sorbitan monolaurate Sorbitan monooleate Sorbitan monopalmitate Sorbitan monostearate Sorbitan sesquioleate Sorbitan trioleate Water... 

Specific gravity Sorbitan laurate Sorbitan oleate Sorbitan sesquioleate Melting point... 

Tetrafluoroethane is a hydrofluorocarbon (HFC) or hydro-fluoroalkane (HFA) aerosol propellant (contains hydrogen, fluorine, and carbon) as contrasted to a CFC (chlorine, fluorine, and carbon). The lack of chlorine in the molecule and the presence of hydrogen reduces the ozone depletion activity to practically zero. Hence tetrafluoroethane can be considered as an alternative to CFCs in the formulation of metered-dose inhalers (MDIs). It has replaced CFC-12 as a refrigerant since it has essentially the same vapor pressure. Its very low Kauri-butanol value and solubility parameter indicate that it is not a good solvent for the commonly used surfactants for MDIs. Sorbitan trioleate, sorbitan sesquioleate, oleic acid, and soya lecithin show limited solubility in tetrafluoroethane and the amount of surfactant that actually dissolves may not be sufficient to keep a drug readily dispersed. 

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