Solvent, solvents methyl isobutyl ketone

Dilevalol DBTA Salt to Dilevalol Hydrochloride. Very little improvement in the RR composition results from the transformation of dilevalol DBTA salt to dilevalol hydrochloride. Ethyl acetate was used as the solvent vehicle in early work. In a search for a more stable solvent methyl isobutyl ketone (MIBK) was selected as the best alternative. DBTA was removed by extraction into water with sodium hydroxide (DBTA of excellent quality was recovered from the aqueous phase in high yield >90%). The MIBK solution of dilevalol was then treated with hydrochloride acid to precipitate dilevalol hydrochloride (Scheme 9). The pH needed for maximum efficiency in the crystallization of dilevalol hydrochloride was 0.5 (this is in sharp contrast to the pH required for maximum efficiency in the crystallization of labetalol hydrochloride—pH 3.0). It should also be noted that dilevalol hydrochloride could not be handled in stainless steel equipment. Hastelloy, plastic or ceramic equipment was employed to eliminate the risk of coloration of dilevalol hydrochloride by traces of iron compounds. The plant equipment layout for this step is shown in Figure 5. 

The most effective solvents for use in atomic absorption are medium weight, low volatile aliphatics, alcohols and ketones. Frequently used solvents are methyl isobutyl ketone (MIBK) and ethyl propionate. These solvents have viscosities and surface tensions such that the efficiency of nebulisation is increased. 

Instrument, Instrumentation Lab model 153 solvent, methyl isobutyl ketone aspiration rate, 3-4 ml min mode, 10 sec integration slit width 80 / ... 

Many extraction systems involve three components which form two immiscible phases. For example, acetone and water are miscible in all proportions. When an organic solvent, methyl isobutyl ketone (MIK) is added to a water-rich acetone solution, two phases are formed a water rich phase and an MIK-rich phase, both phases containing all three components. The composition of the two phases can be graphically represented by means of tie lines on a triangle diagram. ... 

The commercial production of the industrial solvent methyl isobutyl ketone (MIBK) is based on metal impregnated polymeric resin (Scheme 11.7). 

To a sample of 200 ml, acetate buffer solution (pH 5) and 0.5 ml of ethyl violet solution (Imgrnl ) are added. The resulting ion pairs of anionic surfactants are floated by bubbling and captured in 5 ml of organic solvent (toluene-methyl isobutyl ketone = 9 1). The organic phase is analyzed by spectrophotometry for anionic surfactants (mainly SDS). 

Two principal solvent-extraction methods are used for the production of high-grade zirconium, based upon the solvents hexone (methyl-isobutyl-ketone) and tributyl phosphate. In both cases, the aim is to purify the zirconium from its chemical homologue, hafnium, but in some variants of the process the other metallic impurities are also removed. It is also possible to obtain the hafnium in a pure condition if required, and to obtain fairly good yields of both zirconium and hafnium. 

Solvents Methyl isobutyl ketone, methyl ethyl ketone, acetone, dimethylformamide, tetrahydrofuran, l-methyl-2-pyrrolidine, acetonitrile and related polar solvents (6, 8,11)... 

Fig. 137. Separation of isomeric monoglycerides and detection of )5-mono-glyceridfes in the human intestine [60]. Adsorbent hydroxylapatite solvent methyl isobutyl ketone temperature + 10° C time of run 1 h spray reagent molybdophosphoric acid in ethanol solution amounts 10 jxg of each. 1 artificial mixture of the compounds 2, 3 and 4 2 a-monoolein 3 )5-mono-olein 4 oleic acid 5 lipids from the intestinal contents 6 artificial mixture of the compounds 2, 3 and 4...

W. Lynn Schertz and G. D. Christian, Anal. Chem., 44, 755 (1972). Study of effects of neutral inorganic salts on potentiometrie titration curves of weak bases in nonaqueous solvents. Weak bases used urea, caffeine, Tw-nitroaniline, iV-dimethylaniline, aniline and pyridine. Solvents acetone, methyl isobutyl ketone, 2-butanone. Solutes LiC104, Lil, Mg(C104)2. 

Actinide ions form complex ions with a large number of organic substances (12). Their extractabiUty by these substances varies from element to element and depends markedly on oxidation state. A number of important separation procedures are based on this property. Solvents that behave in this way are thbutyl phosphate, diethyl ether [60-29-7J, ketones such as diisopropyl ketone [565-80-5] or methyl isobutyl ketone [108-10-17, and several glycol ether type solvents such as diethyl CeUosolve [629-14-1] (ethylene glycol diethyl ether) or dibutyl Carbitol [112-73-2] (diethylene glycol dibutyl ether). 

Emulsives are solutions of toxicant in water-immiscible organic solvents, commonly at 15 ndash 50%, with a few percent of surface-active agent to promote emulsification, wetting, and spreading. The choice of solvent is predicated upon solvency, safety to plants and animals, volatility, flammabiUty, compatibihty, odor, and cost. The most commonly used solvents are kerosene, xylenes and related petroleum fractions, methyl isobutyl ketone, and amyl acetate. Water emulsion sprays from such emulsive concentrates are widely used in plant protection and for household insect control. 

Methyl Isobutyl Ketone. Methyl isobutyl ketone (MIBK) (4-methyl-2-pentanone), (CH2)2CHCH2COCH2, is an industrially important solvent which after methyl methacrylate and bisphenol A is the third largest tonnage product obtained from acetone. 

DIBK can be produced by the hydrogenation of phorone which, in turn, is produced by the acid-catalyzed aldol condensation of acetone. It is also a by-product in the manufacture of methyl isobutyl ketone. Diisobutyl ketone ( 1.37/kg, October 1994) is produced in the United States by Union Carbide (Institute, West Virginia) and Eastman (Kingsport, Teimessee) (47), and is mainly used as a coating solvent. Catalytic hydrogenation of diisobutyl ketone produces the alcohol 2,6-dimethyl-4-heptanol [108-82-7]. 

Historically, the Redox process was used to achieve the same purification as in the Purex process (97,129). The reagents were hexone (methyl isobutyl ketone) as the solvent, dichromate as an oxidant, and A1(N02)3 as the salting agent. The chief disadvantages of hexone are its flammability and its solubihty in water. However, because A1(N03)3 collects in the highly radioactive waste, thereby impeding the latter s further processing, the Redox process was abandoned in favor of the Purex process. 

Cya.nideExcha.nge, Acetone cyanohydrin and methyl isobutyl ketone cyanohydrin [4131 -68-4] dissolved in an organic solvent, such as diethyl ether or methyl isobutyl ketone, undergo cyanide exchange with aqueous cyanide ion to yield a significant cyanide carbon isotope separation. The two-phase system yields cyanohydrin enriched in carbon-13 and aqueous cyanide depleted in carbon-13. Fquilibrium is obtained in seconds. 

Procedure has been proposed for the P(V) and As(V) determination based on the selective extraction of ionic associate of Crystal Violet with reduced molybdophosphate with mixture of inert (toluene) and active (methyl isobutyl ketone) solvents. Extraction of reagent is negligible. After concentration determination lower than 10 mol/1 of P(V) and As(V) is possible. 

Obviously, accurate concentrations of other gases or vapors cannot be indicated unless the instrument has been appropriately calibrated for each of these gases. Furthermore, the manufacturer s calibration may not be sufficiently accurate and a correction may be required. For example, a meter reading of 2.0 on the 0 to 10% LEL scale of one instrument would indicate, for a solvent having an LEL of 1.4 %, a concentration of 280 ppm (0.02 x 14,000 ppm). Benzene, methyl isobutyl ketone (MIBK). For example, a meter reading of 2.0 on the O-to-10% LEL scale of one instrument would indicate, for a solvent having an LEL of 1.4%, a concentration of 280 ppm (0.02 x 14,000 ppm). Benzene, methyl isobutyl ketone (MIBK) and toluene all have LEL s of 1.4%, but actual concentrations at a meter... 

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