Softgel

Severe Congestion Tussin Softgels—pseudoephedrine, guaifenesin... 

Dietary supplements are available in a variety of delivery forms such as capsules, tablets, teas, tinctures, extracts, and bulk herbs. Sixty-eight percent of the herbal products available are in the form of a capsule or tablet. Approximately half of the herbal preparations contain a single herb [3]. An example of a softgel is Saw Palmetto Complex by PhytoPharmica. 

Capsules, softgel 30 mg (ofc) Dimetapp, Maximum Strength, Non-Drowsy Liqui-Gels (Whitehall-Robins)... 

Various, DC Softgels (Goldline), Stool Softener (Apothecary), Stool Softener DC (Rugby), Surfak Liquigels (Pharmacia)... 

Softgel 125 mg (Alka-Seltzer Gas Relief, Gas-X, Mylanta Gas), 180 mg (Phazyme),... 

Savio D, Harrasser PC, Basso G. Softgel capsule technology as an enhancer device for the absorption of natural principles in humans. Arzneim Forsch/ Drug Res 1998 48 1104-1106. 

Because of the highly cost-intensive operation of softgel capsule production, it is not possible for formulation scientists to conduct research on all phases of the formulation and process development of soft gelatin capsules. However, based on the unique advantages and special properties of this type of dosage form, the formulators should familiarize themselves with the overall technology and processes involved both in the development and manufacturing aspects. 

Softgel capsules have gained popularity and use in the pharmaceutical industry for human and veterinary use, as an oral dosage form, as suppositories for rectal and vaginal administration, single... 

Softgel capsules come in a variety of shapes, sizes, and colors that may be speciLcto the mani facturer. In Figure 21.1, some representative shapes and sizes are presented. This chapter providi an overview of the manufacturing methods, formulation of the content medicament, composition of the shell, quality control procedures, stability, and shelf-life testing. V fe also discuss in some detail examples of the products formulated in softgel dosage form. 

Jones 3rd W. J. and J. J. Francis. 2000. Softgels Consumer perceptions and market impact relative to other ora dosage formsAdvances in Therapy, 17(5) 213-221. 

Patel M. S., F. S. Morton, and H. Seager. 1989a. Advances in softgel formulation technology. Part 1. Manufacturing Chemist, 60 26-28. 

TindalS. and F. Asgarzadeh. 2006. Laboratory scale softgel encapsulation (Mini-cap). AAPS poster presentation. 

Zuniga Z. R, C. L. Phillips, D. Shugars, J. A. Lyon, S. J. Peroutka, J. Swarbrick, and C. Bon. 2004. Analgesic safety and ef cacy of diclofenac sodium softgels on postoperative third molar extractionJpamal of Oral and Maxillofacial Surgery, 62(7) 806-815. 

The influence of gelatin mass temperature, gelatin ribbon thickness, and die speed on softgel formation and the interactions of these variables were explored by regression analysis as follows ... 

Finished softgel weight = gelatin mass temperature + die speed + gelatin ribbon thickness... 

Fishman, Y., Skin Lotion Composition and Softgel Filled Therewith and Methods for Making and Using Same, U.S. Patent 5,824,323, October 20, 1998. 

Oatmeal cookies, muffins, breads and other foods made with rolled oats, oat bran, or whole oat flour hot and cold breakfast cereals containing whole oats or psyllium seed husk and dietary supplements containing psyllium seed husk Soy beverages, tofu, tempeh, soy-based meat alternatives, and possibly some baked goods Spreads, salad dressings, snack bars, and dietary supplements in softgel form... 

Healthcare, a division of Johnson Johnson, manufactured and marketed Take Control " and Benecol " spreads, respectively. Current Benecol products include Benecol Buttery Taste Spread, Benecol Light Spread, Benecol Olive Spread, Benecol Light Cream Cheese Style Spreads, Benecol Low Fat Bio Yogurts, Benecol Snack Bars, and, as a supplement, Softgels (a nonfood supplement). 

B L (softgel) PreserVision (Bausch and Lomb, Rochester, NY www.bausch.com)... 

---