Sensitivity to chemicals

Krypton clathrates have been prepared with hydroquinone and phenol. 85Kr has found recent application in chemical analysis. By imbedding the isotope in various solids, kryptonates are formed. The activity of these kryptonates is sensitive to chemical reactions at the surface. Estimates of the concentration of reactants are therefore made possible. Krypton is used in certain photographic flash lamps for high-speed photography. Uses thus far have been limited because of its high cost. Krypton gas presently costs about 30/1. 

Klaunig JE, Siglin JC, Schafer ED, et al. 1991. Correlation between species and tissue sensitivity to chemical carcinogenesis in rodents and the induction of DNA synthesis. Prog Clin Biol Res 369 185-194. 

Information about the putative folding of the H,K-ATPase catalytic subunit through the membrane has been obtained by the combined use of hydropathy analysis according to the criteria of Kyte and Doolittle [51], identification of sites sensitive to chemical modification [46,48,50,52-55], and localization of epitopes of monoclonal antibodies [56]. The model of the H,K-ATPase catalytic subunit (Fig. 1) which has emerged from these studies shows ten transmembrane segments and contains cytosolic N- and C-termini [53]. This secondary structure of the catalytic subunit is probably a common feature of the catalytic subunits of P-type ATPases, since evidence supporting a ten a-helical model with cytosolic N- and C-termini has also been published recently for both Ca-ATPase of the sarcoplasmic reticulum and Na,K-ATPase [57-59]. 

The digestive tract contains three types of sensory receptors that are sensitive to chemical or mechanical changes within the system. These include ... 

A review of the literature on chemical-induced immunosuppression in rats and mice, exposed during the pre- and/or postnatal period, was compared to exposure of adults. Five known immunosuppressants (i.e., TCDD, TBTO, DES, Pb, and diazepam) were reviewed. The data revealed that the developing immune system was more sensitive to chemical exposure than the mature immune system. Based on these evaluations, the authors concluded that it was reasonable to assume that testing only in adults would not provide a sufficient level of sensitivity to define immunotoxicity in the neonate 132. In summary, this chapter provides compelling evidence that the developing, compared to the mature, immune system is more vulnerable to perturbation. 

His seven-year-old daughter, Juanita, is sensitive to chemicals, too. They had to pull the carpet out of her room because the foam padding was making her sick, and she reacts to perfumes and things... 

I don t want to act neurotic about my illness or scare potential roommates off, so I just tell them I m somewhat sensitive to chemicals and fragrances, and they will have to use natural products. A lot of roommates have ended up smoking, so I have to be careful to screen for that now. And this year I ve developed more spine problems, so I need more help around the apartment. I offer to take twenty bucks a month off the rent if they will do the things that I... 

I thought, How can I be sensitive to chemicals I ve spent my life preparing for this career But it was the truth. Every time I would go in the lab I would feel sick I would get out and I would feel better. But I was still hanging onto my career and business. 

I have some shame about my lifestyle now. For most of the past seven years I ve lived in my car because I m disabled from sensitivities to chemicals and electromagnetic fields (EMFs), and because of my financial situation. I don t like to use the word disability, because I have hope that I won t always be this way. 

One of the losses Bernard experienced was his dream of earning a doctorate. After he was sensitized to chemicals the classrooms and library made him ill, his cognitive skills were impaired and chronic fatigue limited his activities. 

Reports of heightened sensitivity to chemicals have been documented since the 1800s. Since World War II, there has been a dramatic rise in the manufacture and use of synthesized chemicals like pesticides, plastics, and artificial fragrances, and the incidence of MCS has steadily grown. One of the first doctors to identify the relationship between low-level chemical exposures and chronic illness was Theron Randolph in the 1950s. 

The UV-visible absorption and emission spectra and excited state lifetimes of polymers are sensitive to chemical structure, polymer conformation and molecular environment and thus information concerning these properties is accessible by electronic spectroscopy measurements (4-6). One example of the application of such measurements is given in Figure 3 which illustrates the possible energy dissipation pathways which can occur in a polymer containing aromatic side groups following absorption of radiation. 

The aluminum lake is registered throughout the EC as E 132, in the USA as FD C Blue 2 as a colorant for foodstuffs and pharmaceuticals, provided certain purity conditions are met. Its shade is a bluish red. The pigment is somewhat sensitive to chemicals and to overcoating as well as to light. It is a tinctorially weak product. 

Ground covers in banana plantations are favorable for retention of moisture. A desirable ground cover consists of broad-leafed plants, but grasses predominate in many areas. Chemical control of grasses is not favored because banana plants are sensitive to chemicals, so the areas are hand chopped at frequent intervals. The banana plant is a rapid growing, highly succulent, perennial herb that is easily damaged with as little as 7.5 pounds of CMU [3-(p-chlorophenyl)-l,l-dimethylurea] per acre applied in a semicircular strip within 2 feet of the plant. This plant is sensitive to 2,4-D and can be injured by low concentrations. 

Acyl glucuronides (i.e., ester glucuronides of general structure 11.6) are formed as conjugates of carboxylic acids. These compounds are rather uniquely reactive a) they are far more sensitive to chemical hydrolysis than ether... 

LijN has a low decomposition potential, 0.445 V, which limits its usefulness as a practical solid electrolyte in batteries. Various Li3N-derivative phases have been synthesised, such as cubic Li5Nl2 with an antifluorite-derivative structure and a related phase in the system, LijN-Lil-LiOH. Some of these have high conductivity and the latter materials in particular are comparable to those of H-doped LijN. They also have a much higher decomposition voltage, 1.5V, but do suffer from increased sensitivity to chemical attack. 

In general, a diseased state can be expected to influence the sensitivity to chemicals. This is of special concern when the target organ of the toxic effects is affected by the disease or when the metabohsm and ehmination are disturbed. 

To our knowledge, this is the first demonstration of a sensor capable of realtime detection of a TNT plume in the marine environment at standoff distances (up to 100 m from the source) while deployed on an autonomous underwater vehicle. The sensor has shown virtually no sensitivity to chemical interferent during testing in the marine environment. While the sensitivity of the detector is excellent, its sensitivity is not adequate at its present state of development to... 

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