Sensitivity heightened

The Zond VD - 96 portable eddy-current flaw detector-tester is an original Russian development possessing heightened sensitivity for the surface defects and high inspection capacity. (Russia patent Xs 2063025. All-Union state standard certificate of Russian Federation JVa 2846 of 14. 07. 97)... 

Hiroi, N., Brown, J.R., Haile, C.N. et al. FosB mutant mice loss of chronic cocaine induction of Fos-related proteins and heightened sensitivity to cocaine s psychomotor and rewarding effects. Proc. Natl. Acad. Sci. U.S.A. 94 10397, 1997. 

Reports of heightened sensitivity to chemicals have been documented since the 1800s. Since World War II, there has been a dramatic rise in the manufacture and use of synthesized chemicals like pesticides, plastics, and artificial fragrances, and the incidence of MCS has steadily grown. One of the first doctors to identify the relationship between low-level chemical exposures and chronic illness was Theron Randolph in the 1950s. 

Paradoxically, although the overall GST expression and activity were increased, activation of PXR sensitized the response to the oxidative xenotoxicant paraquat in vivo and in cultured cancer cells. Moreover, heightened paraquat sensitivity in... 

Photosensitivity It is advisable to rest a patient s skin until effects of keratolytic agents subside before beginning tretinoin. Minimize exposure to sunlight and sunlamps, and advise patients with sunburn not to use tretinoin until fully recovered because of heightened susceptibility to sunlight as a result of tretinoin use. Patients who undergo considerable sun exposure due to occupation and those with inherent sun sensitivity should exercise particular caution. Use sunscreen products and wear protective clothing over treated areas. Weather extremes, such as wind and cold, also may irritate treated areas. 

There is extensive clinical evidence that NE plays a role in hiunan anxiety. Well-designed psychophysiological studies have been conducted that have documented heightened autonomic or sympathetic nervous system arousal in combat veterans with chronic PTSD. Because central noradrenergic and peripheral sympathetic systems function in concert (Aston-Jones et al. 1991), the data from these psychophysiology investigations are consistent with the hypothesis that noradrenergic hyperreactivity in patients with PTSD may be associated with the conditioned or sensitized responses to specific traumatic stimuli. 

Heightened sensitivity to alcohol in individuals of Oriental origin is another example of a genetically determined increased response. 

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