Schedule of drug

Goldberg SR, KeUeher RT, Morse WH (1975) Second-order schedules of drug injection. Fed Proc 34 1771-1776... 

Schindler CW, PanlUio LV, Goldberg SR (2002) Second-order schedules of drug selfadministration in animals. Psychopharmacology 163 327-344. 

The scheduling of drugs is performed under State and Territory (henceforth referred to as State) legislation controlling access to medicines, but is coordinated at a national level to ensure uniformity except in exceptional circumstances. 

Intensive intermittent schedules of drug treatment should allow time for recovery from the acute toxic effects of antineoplastic agents, primarily bone marrow toxicity. The use of non-myelosuppressive agents can be considered during the recovery period, especially for treatment of fast-growing cancers. 

The Comprehensive Drug Abuse and Control Act of 1970 classified drugs based on their potential for abuse and set criminal punishments for five different classes or schedules of drugs. 

Numerical simulations therefore indicate that the least damage to the cells occurs when the peak of 5-FU circadian delivery is at 4 a.m., and when cells are well synchronized, i.e., when cell cycle variability V is lowest. In contrast, when the peak of 5-FU circadian delivery is at 4 p.m., cytotoxicity is enhanced when cells are well synchronized. The cytotoxic effect of the drug, therefore, can be enhanced or diminished by increased cell cycle synchronization, depending on the relative phases of the circadian schedule of drug delivery and the cell cycle entrained by the circadian clock. Continuous infusion of 5-FU is nearly as toxic as the most cytotoxic circadian pattern of anticancer drug delivery. 

Figure 2.3 This table explains the formal scheduling of drugs according to the Controlled Substances Act of 1970. Drugs are classified based upon their medical uses and potential for abuse. Although some states list Rohypnol in Schedule I, the federal government currently places the drug in Schedule IV.

Standard for Uniform Schedule of Drugs and Poisons Therapeutic Goods Administration Therapeutic Goods Administration Laboratories Therapeutic Goods Order... 

Risk management programs are not a new invention (e.g. Scheduling of drugs with abuse liability). There are classes of drugs for which risk management programs are clearly indicated beyond those that are routinely required for product approval and... 

Solinas M, Panlilio LV, Antoniou K, Pappas LA, Goldberg SR. The cannabinoid CB 1 antagonist N-piperidinyl-5-(4-chlorophenyl)-l-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxamide (SR-141716A) differentially alters the reinforcing effects of heroin under continuous reinforcement, fixed ratio, and progressive ratio schedules of drug self-administration in rats. J. Pharmacol. Exp. Ther. 306, 93-102 (2003). 

We addressed the question as to whether nobiletin inhibits the priming and/or activation stages in mouse skin using the double-TPA-application method, the time schedule of drug applications in each group being shown in Table 1. Groups 1 and 2 represent... 

Dose (mg/kg) Schedule of Drug Administration % Increase in Lifespan Long-term Survivors Maximum Weight Loss3(%)... 

The Standard for the Uniform Scheduling of Drugs and Poisons provides for mandatory warning labelling of containers when certain scheduled substances have been added to the cosmetic. 

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