Responsibility of the producer

All details about starting materials and central production features should be known, in order to define exactly the status natural of a flavouring substance. In principle, the burden of proof is the responsibility of the producer. If necessary, production documents should be disclosed, in order to get objective authenticity assessment by qualified and authorised experts. Constructive cooperation between food researchers, the food industry and authorities will be stimulating to quality assessment in the food industry and will enhance consumer confidence [83]. 

Within Chemical Leasing business models, the responsibility of the producer and service provider is extended and may include the management of the entire life cycle. 

Impurities, reaction and degradation products of the authorised substances are usually not evaluated unless listed in restrictions and specifications for the authorised substance. They remain the responsibility of the producer of the material and article who has to take care that they do not migrate in quantities that pose a health risk. 

For releasing materials it is likely that there will be a focus on the releasing component and its authorisation as a food additive, including any quantitative restriction or a restriction on the types of food. The information on efficacy may be important, e.g., in the case of a released preservative the final efficacy in the food should be demonstrated. A general rule may be considered that if the released component shows insufficient or no technical effect on the food, then the food additive does not comply with the requirements on food additives or any other relevant regulation on the composition of food and its additives, e.g., the requirements on food flavours. As a consequence such a material may not obtain a favourable opinion. Some information may be requested on the carrier of the releasing substance, but as this will not be part of an authorisation the safety of the carrier is the responsibility of the producer and the final user. In many cases the carrier may be subject to other provision on food contact materials. In principle the carrier should be inert and should not migrate to the food at an unacceptable concentration. 

When applying ChL business models, the producer does not just provide the chemical but also his know-how on how to reduce the consumption of chemicals and how to optimize the conditions of use. While in the traditional model the responsibility of the producer ends when the chemical is sold, in ChL business models the producer remains responsible for the chemical during its whole life cycle, including its use and disposal. 

The storage of preformed hormone molecules in secretory vesicles allows for a rapid response of the producing cells to metabolic signals. As soon as the appropriate signal is received the vesicles fuse with plasma membrane and (via exocytosis) release their contents into the bloodstream. 

A number of different strategies have been described to exploit the biosynthetic potential of myxobacteria and other microorganisms. " As the production of secondary metabolites is often a specific response of the producing organism to the environmental conditions,a simple way to trigger the production of new compounds is to vary the cultivation conditions. Indeed, growth conditions for strains of different myxobacter-ial species in liquid culture have been established, hut even today these procedures are far from routine, and have to be developed specifically for each strain. ... 

If the specification for concrete is correct, there should be no need for addition of water at the site. EN 206 forbids any addition of water and admixture at delivery, unless in special cases where, under the responsibility of the producer, it is used to bring the con-... 

Another future trend is the idea of chemical leasing (www.chemicaUeasing.com), a novel business model of sustainable management of chemicals, in which the responsibility of the producer increases as the producer no longer just sells the chemical but remains the owner of the chemical. As such the producer assists in textile processing and is responsible for the waste management of the used chemicals. This model is intended to promote more successful chemical management. 

Hazard classification is the responsibility of the producers and importers of the materials, who must then pass that information to the prmchasers and end-users of the products. 

Hazard classification is the responsibility of the producers and importers of the materials, who must then pass that information to the purchasers and end-users of the products. Employers that don t produce or import chemicals need only focus on those parts of the rule that deal with establishing a workplace program and communicating information to their workers. (Note If employers create mixtures in the workplace, there will be more responsibility and requirements than for employers who simply use chemicals that have already been evaluated and classified.)... 

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