Request for application

NIH Guide. Metabolomics Technology Development.htm, Request for Application-RM-04-002. http //www.nih.gov [accessed August 3,2007]. 

Regier, D. A., 8c Leshner, A. I. (1992, February). Request for applications Cooperative agreement for a multi-site, multimodel treatment study of attention-deficit hyperactivity disorder (ADHD)/attention-deficit disorder (ADD) (Rep. MH-92-03). Washington, DC Department of Health and Human Services. 

JChemPaint is a chemical structure drawing applet. The noteworthy characteristic of this 2D molecule editor is that it is an open source program [208]. This means that the software and the source code of the program are freely available. Every programmer or interested person can participate and enter individual special requests for further development of the application. 

Patent laws provide for several stages in the life of an application for a patent on an invention. The pattern followed by patent laws in effect in most industrialized countries during the nineteenth and early twentieth centuries, and still in effect in the United States in 1995, calls for the examination of all patent appHcations to certify that the claimed invention meets the national standards for novelty, usehilness, and inventiveness. The owner of the technology to be patented files appHcation papers that include a specification containing a description of the invention to be patented (called the disclosure) and claims defining the limits of the invention to be protected by the patent, a formal request for the issuance of a patent, and fees. Drawings of devices and apparatuses, electrical circuits, flow charts, etc, are an important part of the disclosures of most nonchemical and many chemical patents. 

Section 6. Regulatory Requirements. This section describes a few of the ways that a software application can explain the requirements under Title III and assist in compliance with requirements, such as tracking deadlines and responding to requests for information. 

The following listing of data to be supplied to manufacturers when ordering motors or requesting bids is based on the requirements and recommendations of a number of representative manufacturers. This list is split into vital and desirable information and is intended as a checklist in preparing both requisitions and purchase orders. By using this list, you will give the manufacturer a clear picture of your needs for most motor applications in the oil and petrochemical industries and eliminate call-backs, requests for supplementary information, and so on. 

Produced in this way, these materials can be less reliable, with the introduction of unwanted tramp elements. Where proving tests have indicated the suitability of a proprietary alloy for specific application, the same source of material should be used for construction. Published compositional data are typical values cast analyses should be requested for critical applications. 

The ratio between length and diameter of the PB cells was about 1 1. For application in cars, more powerful cells have been requested. Recently it was reported [15] that the ratio of length to diameter was increased to 2 1 without changing the mass of sodium or sulfur, i.e., the surface area of the / " —alumina was increased but the capacity of the cells remained unchanged. This results in higher power and energy densities (Table 4). 

Requests for permission to conduct clinical trials with pharmaceuticals in the US are termed Investigational New Drug Applications (INDs). The applications are actually a request for an exemption to supply a drug without a marketing authorisation. A cover sheet (Form 1571) must accompany the application. This cover sheet should also be used with each subsequent communication with the FDA, with each form consecutively numbered, starting at 000 for the initial submission. A copy of the form is shovm in Figure 5.6. 

For a manufacturer the difficulty is to estimate future developments or trends in NMR microscopy. Based on dedicated laboratory-made hardware developed by the NMR microscopy users and on their requests for new commercial hardware and software, the following topics could become more important micro-coil applications, multiple receiver systems and multi-coil arrangements, NMR microscopy at very high magnetic fields, MAS imaging and localized 1H MAS spectroscopy and localized single-shot 2D spectroscopy. There are no clear-cut distinctions between most of the individual topics, as will be discussed in the following sections. 

In the cases where EPA has formally required such testing, the manufacturers have withdrawn their applications and suspended plans to produce the chemicals. While the decision not to produce a potentially toxic substance may serve the goal of TSCA to identify and prevent hazards before people are exposed, how can one quantitate the health impact of the manufacturers decisions I pose this question rhetorically, since EPA s requests for additional testing stemmed from a data base inadequate to assess risk. In other words, since there was not enough information in the first place to know whether there might even be a substantial health risk, it would be impossible to estimate the health impact of deciding not to produce such chemicals. 

The second major change enacted under the 1962 amendment was the change in the approval process from premarket notification to a premarket approval system. Under the terms of the 1938 law, an NDA would take elfect automatically if the FDA did not respond. For example, the only reason thalidomide was not approved was because Dr. Kelsey returned the application to the sponsor with a request for more information. In contrast, the 1962 law required affirmative FDA action before a drug could be put on the market. Under the terms of the 1962 amendments, the FDA was also empowered to withdraw NDA approval and remove the drug from the market for a variety of reasons, including new evidence that the product was unsafe or that the sponsor had misrepresented or under-reported data. 

The purposes of the EDS for each technology were to (1) support the certification decision of the Under Secretary of Defense for Acquisition and Technology, as directed by Public Law 105-261 (2) support the development of a request for proposal (RFP) for a pilot facility and (3) support the documentation requirements for compliance with the National Environmental Policy Act (NEPA) and the Resource Conservation and Recovery Act (RCRA) permit application. Each EDS required the development of an EDP and experimental tests to acquire necessary data that had not been obtained during the demonstration test phase. 

A requirement to provide a Substitution Plan with all applications for an authorisation will prevent unnecessary requests for authorisation and focus attention on safer chemicals. If substitution is not currently feasible for a particular use, the use of an authorised chemical would be allowed under a strict risk management regime, providing social need could be demonstrated and a positive cost/benefit analysis provided. The authorisation would be time-limited to allow the development of safer substitutes, and manufacturers and/or users would be required to produce a substitution development plan to enable substitution to take place before the authorisation expires. 

Within the period of examination of the application for an opinion, the Ethics Committee may send a single request for information supplementary to that already supplied by the applicant. The period laid down in paragraph 5 shall be suspended until receipt of the supplementary information. 

The Violent Crime Control and Law Enforcement Act of 1994 made further changes to the system. License holders are now photographed and fingerprinted and are required to comply with applicable state and local laws. Dealers must report any thefts of weapons within 48 hours and must immediately respond to the federal Bureau of Alcohol, Ttibacco, and Firearms requests for firearm traces. 

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