Investigation Report

Slags, U.S. Bureau of Mines Report Investigation 6317, Department of Interior, Washington, D.C., 1963. 

Sihcon carbide grains were reduced from 100-200 mesh to 80 percent below 1 [Lm in a version of stirred bead miU, using 20-30 mesh silicon carbide as media (Hoyer, Report Investigations U.S. Bureau Mines 9097, 9 pp., 1987). 

Check whether a documented system is in place, which covers the reporting, investigation, root cause analysis and corrective actions taken. 

Management must institute procedures to assess levels of compliance with agreed standards for safety. Techniques include environmental and/or biological monitoring, health surveillance, safety audits, safety inspections, and procedures for accident reporting, investigation and analysis. Communication is essential, e.g. by provision of information (on specific chemicals, processes, etc.), safety meetings, notices, safety bulletins etc. 

MW is often taken as the size descriptor of choice, while it is easy to calculate and is in the chemist s mind. However, other size and shape properties are equally simple to calculate, and may offer a better guide to estimate potential for permeability. Thus far no systematic work has been reported investigating this in detail. Cross-sectional area Ad obtained from surface activity measurements have been reported as a useful size descriptor to discriminate compounds which can access the brain (Ad<80A ) of those that are too large to cross the blood-brain barrier (BBB) [55]. Similar studies have been performed to define a cut-off for oral absorption [56]. 

It should additionally be noted that a number of the paths of the schemes above have received some confirmation in a number of literature reports dealing with the photolysis and photo-oxidation of other polyesters [32-35], Because these reports investigated poly(butylene terephthalate) (PBT), poly(ethylene naphthalate) and poly(butylene naphthalate), however, they may not have direct application to understanding of the processes involved in PET and PECT and so have not been discussed in this present chapter. All do contain support for the formation of radicals leading to CO and C02 evolution, as well as the hydrogen abstraction at glycolic carbons to form hydroperoxides which then decompose to form alkoxy radicals and the hydroxyl radical. These species then were postulated to undergo further reaction consistent with what we have proposed above. 

All personnel involved in GMP production of drugs have to take ownership of quality. It is a requirement that processes and equipment for drug manufacturing must be approved and operated by trained, qualified personnel. Quality-related activities have to be recorded to enable traceability of data and information. Deviations and excursions of processes and results from specified conditions or criteria have to be reported, investigated, and resolved. Drug products have to be tested and must meet specifications before being... 

Management s charter to the team must include management s expectations for accurately reporting investigation outcomes. However, assigning blame or recommending disciplinary actions should not be part of a team s charter. 

Reporting, investigating, and documenting near misses as well as incidents to demonstrate the company s commitment to learning where there are weaknesses and to improving risk control... 

Turkey reports investigating applications of Boron compounds. To this end, Turkey is establishing the Boron Institute, which will investigate new application areas for boron and its compounds. 

The etch rate of silicon in KOH may vary from as low as 0.1 nm s in dilute solution at room temperature to as high as 200 nm s in 40% KOH near 90 °C. The etch rate of silicon single crystals always depends on the surface plane orientation in all dissolving solutions, but the effect is maximum for alkaline solutions. The (111) surface is the slowest etching plane in all reported investigations. This result can be convincingly correlated by the back bond theory, that is, the surface atoms on the (111) plane have 3 bonds connected to... 

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